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| The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, SG Rosado, D Rosebrock, ... Nature, 122–128, 2020 | 841 | 2020 |
| Neoantigen-directed immune escape in lung cancer evolution R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ... Nature 567 (7749), 479-485, 2019 | 722 | 2019 |
| Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ... Nature genetics 52 (3), 306-319, 2020 | 329 | 2020 |
| Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-2254. e39, 2021 | 328* | 2021 |
| Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 266 | 2020 |
| Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization F Christ, S Shaw, J Demeulemeester, BA Desimmie, A Marchand, S Butler, ... Antimicrobial agents and chemotherapy 56 (8), 4365-4374, 2012 | 213 | 2012 |
| The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites J De Rijck, C de Kogel, J Demeulemeester, S Vets, S El Ashkar, N Malani, ... Cell reports 5 (4), 886-894, 2013 | 190 | 2013 |
| LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions BA Desimmie, R Schrijvers, J Demeulemeester, D Borrenberghs, ... Retrovirology 10, 1-16, 2013 | 169 | 2013 |
| LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs R Schrijvers, J De Rijck, J Demeulemeester, N Adachi, S Vets, K Ronen, ... PLoS pathogens 8 (3), e1002558, 2012 | 150 | 2012 |
| Recurrent rearrangements of FOS and FOSB define osteoblastoma MW Fittall, W Mifsud, N Pillay, H Ye, AC Strobl, A Verfaillie, ... Nature communications 9 (1), 2150, 2018 | 117 | 2018 |
| LEDGIN-mediated inhibition of integrase–LEDGF/p75 interaction reduces reactivation of residual latent HIV LS Vranckx, J Demeulemeester, S Saleh, A Boll, G Vansant, R Schrijvers, ... EBioMedicine 8, 248-264, 2016 | 111 | 2016 |
| Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma O Marin-Bejar, A Rogiers, M Dewaele, J Femel, P Karras, J Pozniak, ... Cancer Cell 39 (8), 1135-1149. e8, 2021 | 93 | 2021 |
| Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing J Demeulemeester, P Kumar, EK Mřller, S Nord, DC Wedge, A Peterson, ... Genome biology 17, 1-15, 2016 | 89 | 2016 |
| Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors J Cheng, J Demeulemeester, DC Wedge, HKM Vollan, JJ Pitt, ... Nature Communications 8 (1), 1221, 2017 | 87 | 2017 |
| Retroviral integration: site matters: mechanisms and consequences of retroviral integration site selection J Demeulemeester, J De Rijck, R Gijsbers, Z Debyser Bioessays 37 (11), 1202-1214, 2015 | 87 | 2015 |
| LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006–2014) J Demeulemeester, P Chaltin, A Marchand, M De Maeyer, Z Debyser, ... Expert opinion on therapeutic patents 24 (6), 609-632, 2014 | 85 | 2014 |
| 4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors M Billamboz, V Suchaud, F Bailly, C Lion, J Demeulemeester, C Calmels, ... ACS Medicinal Chemistry Letters 4 (7), 606-611, 2013 | 68 | 2013 |
| Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif P Tesina, K Čermáková, M Hořejší, K Procházková, M Fábry, S Sharma, ... Nature communications 6 (1), 7968, 2015 | 59 | 2015 |
| Interplay between HIV entry and transportin-SR2 dependency W Thys, S De Houwer, J Demeulemeester, O Taltynov, ... Retrovirology 8 (7), 2011 | 56 | 2011 |
zeger debyserKU LeuvenVerified email at med.kuleuven.be
