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Farren Isaacs
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Programming cells by multiplex genome engineering and accelerated evolution
HH Wang, FJ Isaacs, PA Carr, ZZ Sun, G Xu, CR Forest, GM Church
Nature 460 (7257), 894-898, 2009
16352009
Genomically recoded organisms expand biological functions
MJ Lajoie, AJ Rovner, DB Goodman, HR Aerni, AD Haimovich, ...
science 342 (6156), 357-360, 2013
7932013
Computational studies of gene regulatory networks: in numero molecular biology
J Hasty, D McMillen, F Isaacs, JJ Collins
Nature Reviews Genetics 2 (4), 268-279, 2001
7862001
Phenotypic consequences of promoter-mediated transcriptional noise
WJ Blake, G Balázsi, MA Kohanski, FJ Isaacs, KF Murphy, Y Kuang, ...
Molecular cell 24 (6), 853-865, 2006
6772006
Engineered riboregulators enable post-transcriptional control of gene expression
FJ Isaacs, DJ Dwyer, C Ding, DD Pervouchine, CR Cantor, JJ Collins
Nature biotechnology 22 (7), 841-847, 2004
6612004
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
FJ Isaacs, PA Carr, HH Wang, MJ Lajoie, B Sterling, L Kraal, AC Tolonen, ...
Science 333 (6040), 348-353, 2011
6112011
Prediction and measurement of an autoregulatory genetic module
FJ Isaacs, J Hasty, CR Cantor, JJ Collins
Proceedings of the National Academy of Sciences 100 (13), 7714-7719, 2003
5492003
RNA synthetic biology
FJ Isaacs, DJ Dwyer, JJ Collins
Nature biotechnology 24 (5), 545-554, 2006
4422006
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes
L Bazak, A Haviv, M Barak, J Jacob-Hirsch, P Deng, R Zhang, FJ Isaacs, ...
Genome research 24 (3), 365-376, 2014
4172014
The real cost of sequencing: scaling computation to keep pace with data generation
P Muir, S Li, S Lou, D Wang, DJ Spakowicz, L Salichos, J Zhang, ...
Genome biology 17 (1), 1-9, 2016
3922016
Designer gene networks: Towards fundamental cellular control
J Hasty, F Isaacs, M Dolnik, D McMillen, JJ Collins
Chaos: An Interdisciplinary Journal of Nonlinear Science 11 (1), 207-220, 2001
3412001
Recoded organisms engineered to depend on synthetic amino acids
AJ Rovner, AD Haimovich, SR Katz, Z Li, MW Grome, BM Gassaway, ...
Nature 518 (7537), 89-93, 2015
3002015
Engineering an allosteric transcription factor to respond to new ligands
ND Taylor, AS Garruss, R Moretti, S Chan, MA Arbing, D Cascio, ...
Nature methods 13 (2), 177-183, 2016
2432016
The genome project-write
JD Boeke, G Church, A Hessel, NJ Kelley, A Arkin, Y Cai, R Carlson, ...
Science 353 (6295), 126-127, 2016
2242016
Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids
M Amiram, AD Haimovich, C Fan, YS Wang, HR Aerni, I Ntai, DW Moonan, ...
Nature biotechnology 33 (12), 1272-1279, 2015
2222015
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
JM Callura, DJ Dwyer, FJ Isaacs, CR Cantor, JJ Collins
Proceedings of the National Academy of Sciences 107 (36), 15898-15903, 2010
1942010
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
RW Martin, BJ Des Soye, YC Kwon, J Kay, RG Davis, PM Thomas, ...
Nature communications 9 (1), 1-9, 2018
1492018
Cell-free Protein Synthesis from a Release Factor 1 Deficient Escherichia coli Activates Efficient and Multiple Site-specific Nonstandard Amino Acid Incorporation
SH Hong, I Ntai, AD Haimovich, NL Kelleher, FJ Isaacs, MC Jewett
ACS synthetic biology 3 (6), 398-409, 2014
1392014
Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection
PA Carr, HH Wang, B Sterling, FJ Isaacs, MJ Lajoie, G Xu, GM Church, ...
Nucleic acids research 40 (17), e132-e132, 2012
1222012
Crystal structure of an insect antifreeze protein and its implications for ice binding
A Hakim, JB Nguyen, K Basu, DF Zhu, D Thakral, PL Davies, FJ Isaacs, ...
Journal of Biological Chemistry 288 (17), 12295-12304, 2013
1202013
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Articles 1–20