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| Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells EP Mimitou, A Cheng, A Montalbano, S Hao, M Stoeckius, M Legut, ... Nature methods 16 (5), 409-412, 2019 | 409 | 2019 |
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| JAK–STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response M Kleppe, M Kwak, P Koppikar, M Riester, M Keller, L Bastian, T Hricik, ... Cancer discovery 5 (3), 316-331, 2015 | 302* | 2015 |
| Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ... Cancer cell 33 (1), 29-43. e7, 2018 | 271 | 2018 |
| Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ... Nature biotechnology 39 (10), 1246-1258, 2021 | 267 | 2021 |
| Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis AD Viny, CJ Ott, B Spitzer, M Rivas, C Meydan, E Papalexi, D Yelin, ... Journal of Experimental Medicine 212 (11), 1819-1832, 2015 | 155 | 2015 |
| Molecular transitions in early progenitors during human cord blood hematopoiesis S Zheng, E Papalexi, A Butler, W Stephenson, R Satija Molecular systems biology 14 (3), e8041, 2018 | 144 | 2018 |
| Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens E Papalexi, EP Mimitou, AW Butler, S Foster, B Bracken, WM Mauck III, ... Nature genetics 53 (3), 322-331, 2021 | 114 | 2021 |
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| Kinetics of adult hematopoietic stem cell differentiation in vivo S Upadhaya, CM Sawai, E Papalexi, A Rashidfarrokhi, G Jang, ... Journal of Experimental Medicine 215 (11), 2815-2832, 2018 | 75 | 2018 |
| Jak1 integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis M Kleppe, MH Spitzer, S Li, CE Hill, L Dong, E Papalexi, S De Groote, ... Cell stem cell 21 (4), 489-501. e7, 2017 | 75 | 2017 |
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| Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias N Kucine, S Marubayashi, N Bhagwat, E Papalexi, P Koppikar, ... Blood, The Journal of the American Society of Hematology 126 (22), 2479-2483, 2015 | 42 | 2015 |
| A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness KB Kaufmann, AGX Zeng, E Coyaud, L Garcia-Prat, E Papalexi, ... Nature immunology 22 (6), 723-734, 2021 | 33 | 2021 |
| Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq HH Wessels, A Méndez-Mancilla, Y Hao, E Papalexi, WM Mauck III, L Lu, ... Nature methods 20 (1), 86-94, 2023 | 27 | 2023 |
| Lysine-specific histone demethylase, LSD1,(KDM1A) as a novel therapeutic target in myeloproliferative neoplasms M Kleppe, K Shank, P Efthymia, H Riehnhoff, RL Levine Blood 126 (23), 601, 2015 | 14 | 2015 |
