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Hanxi Xiao
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Metabolic regulation by PD-1 signaling promotes long-lived quiescent CD8 T cell memory in mice
V Kalia, Y Yuzefpolskiy, A Vegaraju, H Xiao, F Baumann, S Jatav, ...
Science translational medicine 13 (615), eaba6006, 2021
432021
Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
S Grebinoski, Q Zhang, AR Cillo, S Manne, H Xiao, EA Brunazzi, T Tabib, ...
Nature immunology 23 (6), 868-877, 2022
412022
Autocrine and paracrine IL-2 signals collaborate to regulate distinct phases of CD8 T cell memory
R Toumi, Y Yuzefpolskiy, A Vegaraju, H Xiao, KA Smith, S Sarkar, V Kalia
Cell Reports 39 (2), 2022
242022
Programming of CD8 T cell quantity and polyfunctionality by direct IL-1 signals
S Sarkar, Y Yuzefpolskiy, H Xiao, FM Baumann, S Yim, DJ Lee, ...
The Journal of Immunology 201 (12), 3641-3650, 2018
222018
Cell Type–Specific Biomarkers of Systemic Sclerosis Disease Severity Capture Cell‐Intrinsic and Cell‐Extrinsic Circuits
JS Berkowitz, T Tabib, H Xiao, GM Sadej, D Khanna, P Fuschiotti, ...
Arthritis & Rheumatology 75 (10), 1819-1830, 2023
52023
Functional reprogramming of monocytes in acute and convalescent severe COVID-19 patients
E Brauns, A Azouz, D Grimaldi, H Xiao, S Thomas, M Nguyen, ...
22021
SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains
J Rahimikollu, H Xiao, AE Rosengart, ABI Rosen, T Tabib, PM Zdinak, ...
Nature Methods, 1-11, 2024
12024
From bench to bedside via bytes: Multi-omic immunoprofiling and integration using machine learning and network approaches
H Xiao, A Rosen, P Chhibbar, L Moise, J Das
Human Vaccines & Immunotherapeutics 19 (3), 2282803, 2023
12023
Il-2 Signals Program the Fate of Exhausted Cd8 T Cells
V Kalia, H Xiao, Y Yuzefpolskiy, S Sarkar
The Journal of Immunology 202 (1_Supplement), 181.24-181.24, 2019
12019
Spatial microniches of IL-2 synergize with IL-10 to drive lung migratory Th2 cells in response to inhaled allergen
A Poholek, K He, H Xiao, W MacDonald, I Mehta, A Kishore, A Vincent, ...
2023
Programming of checkpoint blockade responsive exhausted T cells by rheostatic IL-2 signals during priming by dendritic cells
S Sarkar, R Toumi, H Xiao, T Pulliam, J Reed, P Nghiem, V Kalia
The Journal of Immunology 210 (1_Supplement), 83.16-83.16, 2023
2023
Tempered IL-2 Signals Program PD-1 Checkpoint Blockade-Responsive Stem-like Exhausted T Cells During Priming
V Kalia, J Reed, A Khanna, R Toumi, H Xiao, T Pulliam, R Deo, P Nghiem, ...
bioRxiv, 2023.05. 25.541936, 2023
2023
Early heterogeneity of IL2R□ expression influences the programming of exhausted CD8T cells during chronic infection
R Toumi, H Xiao, R Deo, SJ Reed, S Sarkar, V Kalia
The Journal of Immunology 208 (1_Supplement), 182.30-182.30, 2022
2022
PD-1 Signals are Critical for Homeostatic Maintenance of Memory CD8 T Cells
S Sarkar, Y Yuzefpolskiy, A Vegaraju, H Xiao, F Baumann, S Jatav, ...
The Journal of Immunology 204 (1_Supplement), 81.5-81.5, 2020
2020
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