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Sandra Misale
Sandra Misale
Assistant Professor of Oncology, Johns Hopkins University School of Medicine
Verified email at mskcc.org
Title
Cited by
Cited by
Year
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...
Nature 486 (7404), 532-536, 2012
20092012
Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution
S Misale, F Di Nicolantonio, A Sartore-Bianchi, S Siena, A Bardelli
Cancer discovery 4 (11), 1269-1280, 2014
4922014
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer
M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ...
Cell 178 (1), 160-175. e27, 2019
4352019
Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer
M Russo, S Misale, G Wei, G Siravegna, G Crisafulli, L Lazzari, G Corti, ...
Cancer discovery 6 (1), 36-44, 2016
2942016
Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer
S Misale, S Arena, S Lamba, G Siravegna, A Lallo, S Hobor, M Russo, ...
Science translational medicine 6 (224), 224ra26-224ra26, 2014
2882014
Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer
S Arena, B Bellosillo, G Siravegna, A Martínez, I Canadas, L Lazzari, ...
Clinical cancer research 21 (9), 2157-2166, 2015
2802015
EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer
V Amodio, R Yaeger, P Arcella, C Cancelliere, S Lamba, A Lorenzato, ...
Cancer discovery 10 (8), 1129-1139, 2020
2732020
KRAS gene amplification in colorectal cancer and impact on response to EGFR‐targeted therapy
E Valtorta, S Misale, A Sartore‐Bianchi, ID Nagtegaal, F Paraf, ...
International journal of cancer 133 (5), 1259-1265, 2013
2202013
KRAS G12C NSCLC models are sensitive to direct targeting of KRAS in combination with PI3K inhibition
S Misale, JP Fatherree, E Cortez, C Li, S Bilton, D Timonina, DT Myers, ...
Clinical Cancer Research 25 (2), 796-807, 2019
2012019
Resistance to TRK inhibition mediated by convergent MAPK pathway activation
E Cocco, AM Schram, A Kulick, S Misale, HH Won, R Yaeger, P Razavi, ...
Nature medicine 25 (9), 1422-1427, 2019
1742019
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers
BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ...
Cancer discovery 10 (5), 674-687, 2020
1732020
Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy
M Di Pilato, EY Kim, BL Cadilha, JN Prüßmann, MN Nasrallah, ...
Nature 570 (7759), 112-116, 2019
1682019
Sensitivity to entrectinib associated with a novel LMNA-NTRK1 gene fusion in metastatic colorectal cancer
A Sartore-Bianchi, E Ardini, R Bosotti, A Amatu, E Valtorta, A Somaschini, ...
Journal of the National Cancer Institute 108 (1), djv306, 2016
1492016
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers
S Misale, I Bozic, J Tong, A Peraza-Penton, A Lallo, F Baldi, KH Lin, ...
Nature communications 6 (1), 8305, 2015
1292015
TGFα and amphiregulin paracrine network promotes resistance to EGFR blockade in colorectal cancer cells
S Hobor, BO Van Emburgh, E Crowley, S Misale, F Di Nicolantonio, ...
Clinical Cancer Research 20 (24), 6429-6438, 2014
1282014
Expanding the Reach of Precision Oncology by Drugging All KRAS Mutants
MH Hofmann, D Gerlach, S Misale, M Petronczki, N Kraut
Cancer Discovery 12 (4), 924-937, 2022
1192022
MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations
S Arena, G Siravegna, B Mussolin, JD Kearns, BB Wolf, S Misale, ...
Science translational medicine 8 (324), 324ra14-324ra14, 2016
972016
STAT3 can serve as a hit in the process of malignant transformation of primary cells
M Demaria, S Misale, C Giorgi, V Miano, A Camporeale, J Campisi, ...
Cell Death & Differentiation 19 (8), 1390-1397, 2012
592012
Anatomic position determines oncogenic specificity in melanoma
JM Weiss, MV Hunter, NM Cruz, A Baggiolini, M Tagore, Y Ma, S Misale, ...
Nature 604 (7905), 354-361, 2022
572022
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
E Cocco, JE Lee, S Kannan, AM Schram, HH Won, S Shifman, A Kulick, ...
Cancer discovery 11 (1), 126-141, 2021
382021
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