| Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones D Castagnolo, F Manetti, M Radi, B Bechi, M Pagano, A De Logu, ... Bioorganic & medicinal chemistry 17 (15), 5716-5721, 2009 | 167 | 2009 |
| Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis D Castagnolo, A De Logu, M Radi, B Bechi, F Manetti, M Magnani, ... Bioorganic & medicinal chemistry 16 (18), 8587-8591, 2008 | 135 | 2008 |
| ATP-competitive inhibitors of mTOR: an update S Schenone, C Brullo, F Musumeci, M Radi, M Botta Current medicinal chemistry 18 (20), 2995-3014, 2011 | 127 | 2011 |
| Vascular endothelial growth factor (VEGF) receptors: drugs and new inhibitors F Musumeci, M Radi, C Brullo, S Schenone Journal of medicinal chemistry 55 (24), 10797-10822, 2012 | 126 | 2012 |
| Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical … S Schenone, M Radi, F Musumeci, C Brullo, M Botta Chemical reviews 114 (14), 7189-7238, 2014 | 86 | 2014 |
| Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2, 3-dihydropyran [2, 3-c] pyrazoles M Radi, V Bernardo, B Bechi, D Castagnolo, M Pagano, M Botta Tetrahedron Letters 50 (47), 6572-6575, 2009 | 86 | 2009 |
| Toward the discovery of novel anti‐HIV drugs. Second‐generation inhibitors of the cellular ATPase DDX3 with improved anti‐HIV activity: Synthesis, structure–activity … G Maga, F Falchi, M Radi, L Botta, G Casaluce, M Bernardini, H Irannejad, ... ChemMedChem 6 (8), 1371-1389, 2011 | 80 | 2011 |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors M Radi, F Falchi, A Garbelli, A Samuele, V Bernardo, S Paolucci, ... Bioorganic & medicinal chemistry letters 22 (5), 2094-2098, 2012 | 78 | 2012 |
| Microwave-enhanced Sonogashira coupling reaction of substituted pyrimidinones and pyrimidine nucleosides E Petricci, M Radi, F Corelli, M Botta Tetrahedron letters 44 (51), 9181-9184, 2003 | 78 | 2003 |
| Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study M Radi, E Dreassi, C Brullo, E Crespan, C Tintori, V Bernardo, M Valoti, ... Journal of medicinal chemistry 54 (8), 2610-2626, 2011 | 70 | 2011 |
| Recent highlights in the synthesis of highly functionalized pyrimidines M Radi, S Schenone, M Botta Organic & biomolecular chemistry 7 (14), 2841-2847, 2009 | 69 | 2009 |
| Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis D Castagnolo, M Radi, F Dessì, F Manetti, M Saddi, R Meleddu, ... Bioorganic & medicinal chemistry letters 19 (8), 2203-2205, 2009 | 64 | 2009 |
| Discovery and SAR of 1, 3, 4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents M Radi, E Crespan, G Botta, F Falchi, G Maga, F Manetti, V Corradi, ... Bioorganic & medicinal chemistry letters 18 (3), 1207-1211, 2008 | 63 | 2008 |
| Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication A Garbelli, M Radi, F Falchi, S Beermann, S Zanoli, F Manetti, U Dietrich, ... Current medicinal chemistry 18 (20), 3015-3027, 2011 | 56 | 2011 |
| New insights into small‐molecule inhibitors of Bcr‐Abl S Schenone, O Bruno, M Radi, M Botta Medicinal research reviews 31 (1), 1-41, 2011 | 54 | 2011 |
| Microwave-assisted acylation of amines, alcohols, and phenols by the use of solid-supported reagents (SSRs) E Petricci, C Mugnaini, M Radi, F Corelli, M Botta The Journal of organic chemistry 69 (23), 7880-7887, 2004 | 50 | 2004 |
| Discovery of Chiral Cyclopropyl Dihydro-Alkylthio-Benzyl-Oxopyrimidine (S-DABO) Derivatives as Potent HIV-1 Reverse Transcriptase Inhibitors with High Activity … M Radi, G Maga, M Alongi, L Angeli, A Samuele, S Zanoli, L Bellucci, ... Journal of medicinal chemistry 52 (3), 840-851, 2009 | 49 | 2009 |
| Practical one-pot two-step protocol for the microwave-assisted synthesis of highly functionalized rhodanine derivatives M Radi, L Botta, G Casaluce, M Bernardini, M Botta Journal of combinatorial chemistry 12 (1), 200-205, 2010 | 48 | 2010 |
| HIV-1 RT inhibitors with a novel mechanism of action: NNRTIs that compete with the nucleotide substrate G Maga, M Radi, MA Gerard, M Botta, E Ennifar Viruses 2 (4), 880-899, 2010 | 46 | 2010 |
| Discovery of multitarget antivirals acting on both the Dengue virus NS5-NS3 interaction and the host Src/Fyn kinases P Vincetti, F Caporuscio, S Kaptein, A Gioiello, V Mancino, Y Suzuki, ... Journal of medicinal chemistry 58 (12), 4964-4975, 2015 | 43 | 2015 |
Giovanni MagaIGM CNRVerified email at igm.cnr.it
