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| Molecular findings among patients referred for clinical whole-exome sequencing Y Yang, DM Muzny, F Xia, Z Niu, R Person, Y Ding, P Ward, A Braxton, ... Jama 312 (18), 1870-1879, 2014 | 1457 | 2014 |
| Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene D Zhou, C Conrad, F Xia, JS Park, B Payer, Y Yin, GY Lauwers, W Thasler, ... Cancer cell 16 (5), 425-438, 2009 | 1023 | 2009 |
| Resolution of disease phenotypes resulting from multilocus genomic variation JE Posey, T Harel, P Liu, JA Rosenfeld, RA James, ZH Coban Akdemir, ... New England Journal of Medicine 376 (1), 21-31, 2017 | 636 | 2017 |
| Asprosin, a fasting-induced glucogenic protein hormone C Romere, C Duerrschmid, J Bournat, P Constable, M Jain, F Xia, ... Cell 165 (3), 566-579, 2016 | 490 | 2016 |
| MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation M Praskova, F Xia, J Avruch Current Biology 18 (5), 311-321, 2008 | 472 | 2008 |
| Use of exome sequencing for infants in intensive care units: ascertainment of severe single-gene disorders and effect on medical management L Meng, M Pammi, A Saronwala, P Magoulas, AR Ghazi, F Vetrini, ... JAMA pediatrics 171 (12), e173438-e173438, 2017 | 413 | 2017 |
| Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism CP Schaaf, ML Gonzalez-Garay, F Xia, L Potocki, KW Gripp, B Zhang, ... Nature genetics 45 (11), 1405-1408, 2013 | 315 | 2013 |
| Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis N Gomez-Ospina, CJ Potter, R Xiao, K Manickam, MS Kim, KH Kim, ... Nature communications 7 (1), 10713, 2016 | 289 | 2016 |
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| Reanalysis of clinical exome sequencing data P Liu, L Meng, EA Normand, F Xia, X Song, A Ghazi, J Rosenfeld, ... New England Journal of Medicine 380 (25), 2478-2480, 2019 | 221 | 2019 |
| JAK signaling globally counteracts heterochromatic gene silencing S Shi, HC Calhoun, F Xia, J Li, L Le, WX Li Nature genetics 38 (9), 1071-1076, 2006 | 206 | 2006 |
| Non-invasive prenatal sequencing for multiple Mendelian monogenic disorders using circulating cell-free fetal DNA J Zhang, J Li, JB Saucier, Y Feng, Y Jiang, J Sinson, AK McCombs, ... Nature medicine 25 (3), 439-447, 2019 | 194 | 2019 |
| USP7 acts as a molecular rheostat to promote WASH-dependent endosomal protein recycling and is mutated in a human neurodevelopmental disorder YH Hao, MD Fountain, KF Tacer, F Xia, W Bi, SHL Kang, A Patel, ... Molecular cell 59 (6), 956-969, 2015 | 191 | 2015 |
| The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes F Mou, M Praskova, F Xia, D Van Buren, H Hock, J Avruch, D Zhou Journal of Experimental Medicine 209 (4), 741-759, 2012 | 175 | 2012 |
| Recurrent de novo and biallelic variation of ATAD3A, encoding a mitochondrial membrane protein, results in distinct neurological syndromes T Harel, WH Yoon, C Garone, S Gu, Z Coban-Akdemir, MK Eldomery, ... The American Journal of Human Genetics 99 (4), 831-845, 2016 | 171 | 2016 |
| Rassf family of tumor suppressor polypeptides J Avruch, R Xavier, N Bardeesy, X Zhang, M Praskova, D Zhou, F Xia Journal of Biological Chemistry 284 (17), 11001-11005, 2009 | 149 | 2009 |
| De novo mutations in protein kinase genes CAMK2A and CAMK2B cause intellectual disability S Küry, GM van Woerden, T Besnard, MP Onori, X Latypova, MC Towne, ... The American Journal of Human Genetics 101 (5), 768-788, 2017 | 144 | 2017 |
Joseph AvruchMassachusetts General HospitalVerified email at molbio.mgh.harvard.edu
