CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ... Cancer discovery 8 (2), 216-233, 2018 | 581 | 2018 |
DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra B Graham, CT Loh, JD Swarbrick, P Ung, J Shin, H Yagi, X Jia, S Chhabra, ... Bioconjugate chemistry 22 (10), 2118-2125, 2011 | 135 | 2011 |
Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics A Boeszoermenyi, S Chhabra, A Dubey, DL Radeva, NT Burdzhiev, ... Nature methods 16 (4), 333-340, 2019 | 92 | 2019 |
A potent and Kv1. 3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases MH Rashid, R Huq, MR Tanner, S Chhabra, KK Khoo, R Estrada, ... Scientific reports 4 (1), 4509, 2014 | 91 | 2014 |
Kv1. 3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases S Chhabra, SC Chang, HM Nguyen, R Huq, MR Tanner, LM Londono, ... The FASEB Journal 28 (9), 3952, 2014 | 89 | 2014 |
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation. Cancer Discov. 2018; 8: 216–233. doi: 10.1158/2159-8290 J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ... CD-17-0915.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 83 | |
Development of highly selective Kv1. 3-blocking peptides based on the sea anemone peptide ShK MW Pennington, SC Chang, S Chauhan, R Huq, RB Tajhya, S Chhabra, ... Marine Drugs 13 (1), 529-542, 2015 | 72 | 2015 |
A potent and selective peptide blocker of the Kv1. 3 channel: prediction from free-energy simulations and experimental confirmation MH Rashid, G Heinzelmann, R Huq, RB Tajhya, SC Chang, S Chhabra, ... PloS one 8 (11), e78712, 2013 | 70 | 2013 |
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins JD Swarbrick, DJ Shaw, S Chhabra, R Ghai, E Valkov, SJ Norwood, ... PLoS One 6 (5), e20420, 2011 | 70 | 2011 |
A novel inhibitor of α9α10 nicotinic acetylcholine receptors from Conus vexillum delineates a new conotoxin superfamily S Luo, S Christensen, D Zhangsun, Y Wu, Y Hu, X Zhu, S Chhabra, ... PloS one 8 (1), e54648, 2013 | 68 | 2013 |
Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets S Chhabra, A Belgi, P Bartels, BJ van Lierop, SD Robinson, SN Kompella, ... Journal of Medicinal Chemistry 57 (23), 9933-9944, 2014 | 66 | 2014 |
An iminodiacetic acid based lanthanide binding tag for paramagnetic exchange NMR spectroscopy JD Swarbrick, P Ung, S Chhabra, B Graham Angewandte Chemie 19 (123), 4495-4498, 2011 | 62 | 2011 |
15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins S Chhabra, P Fischer, K Takeuchi, A Dubey, JJ Ziarek, A Boeszoermenyi, ... Proceedings of the National Academy of Sciences 115 (8), E1710-E1719, 2018 | 58 | 2018 |
Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy JD Swarbrick, P Ung, XC Su, A Maleckis, S Chhabra, T Huber, G Otting, ... Chemical communications 47 (26), 7368-7370, 2011 | 54 | 2011 |
Compact, hydrophilic, lanthanide-binding tags for paramagnetic NMR spectroscopy MD Lee, CT Loh, J Shin, S Chhabra, ML Dennis, G Otting, JD Swarbrick, ... Chemical Science 6 (4), 2614-2624, 2015 | 44 | 2015 |
8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase ML Dennis, MD Lee, JR Harjani, M Ahmed, AJ DeBono, NP Pitcher, ... Chemistry–A European Journal 24 (8), 1922-1930, 2018 | 42 | 2018 |
N‐terminally extended analogues of the K+ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage‐gated potassium channel … SC Chang, R Huq, S Chhabra, C Beeton, MW Pennington, BJ Smith, ... The FEBS journal 282 (12), 2247-2259, 2015 | 38 | 2015 |
A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent BK Yap, EWW Leung, H Yagi, CA Galea, S Chhabra, DK Chalmers, ... Journal of Medicinal Chemistry 57 (16), 7006-7015, 2014 | 36 | 2014 |
Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor S Chhabra, O Dolezal, BM Collins, J Newman, JS Simpson, IG Macreadie, ... PloS one 7 (1), e29444, 2012 | 32 | 2012 |
Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK S Chhabra, N Barlow, O Dolezal, MK Hattarki, J Newman, TS Peat, ... PloS one 8 (4), e59535, 2013 | 23 | 2013 |