| Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury KT Cheng, S Xiong, Z Ye, Z Hong, A Di, KM Tsang, X Gao, S An, M Mittal, ... The Journal of clinical investigation 127 (11), 4124-4135, 2017 | 358 | 2017 |
| The TWIK2 potassium efflux channel in macrophages mediates NLRP3 inflammasome-induced inflammation A Di, S Xiong, Z Ye, RKS Malireddi, S Kometani, M Zhong, M Mittal, ... Immunity 49 (1), 56-65. e4, 2018 | 318 | 2018 |
| mtDNA activates cGAS signaling and suppresses the YAP-mediated endothelial cell proliferation program to promote inflammatory injury LS Huang, Z Hong, W Wu, S Xiong, M Zhong, X Gao, J Rehman, AB Malik Immunity 52 (3), 475-486. e5, 2020 | 249 | 2020 |
| FoxO1 mediates an autofeedback loop regulating SIRT1 expression S Xiong, G Salazar, N Patrushev, RW Alexander Journal of Biological Chemistry 286 (7), 5289-5299, 2011 | 235 | 2011 |
| Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions EE Friedrich, Z Hong, S Xiong, M Zhong, A Di, J Rehman, YA Komarova, ... Proceedings of the National Academy of Sciences 116 (26), 12980-12985, 2019 | 182 | 2019 |
| Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis F Forouzandeh, G Salazar, N Patrushev, S Xiong, L Hilenski, B Fei, ... Journal of the American Heart Association 3 (6), e001202, 2014 | 153 | 2014 |
| IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury S Xiong, Z Hong, LS Huang, Y Tsukasaki, S Nepal, A Di, M Zhong, W Wu, ... The Journal of clinical investigation 130 (7), 3684-3698, 2020 | 131 | 2020 |
| hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling S Xiong, Q Zhao, Z Rong, G Huang, Y Huang, P Chen, S Zhang, L Liu, ... Journal of Biological Chemistry 278 (50), 50273-50282, 2003 | 115 | 2003 |
| PGC-1α modulates telomere function and DNA damage in protecting against aging-related chronic diseases S Xiong, N Patrushev, F Forouzandeh, L Hilenski, RW Alexander Cell reports 12 (9), 1391-1399, 2015 | 106 | 2015 |
| Sox17 is required for endothelial regeneration following inflammation-induced vascular injury M Liu, L Zhang, G Marsboom, A Jambusaria, S Xiong, PT Toth, ... Nature communications 10 (1), 2126, 2019 | 104 | 2019 |
| PGC-1α serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy S Xiong, G Salazar, A San Martin, M Ahmad, N Patrushev, L Hilenski, ... Journal of biological chemistry 285 (4), 2474-2487, 2010 | 91 | 2010 |
| Peroxisome proliferator-activated receptor γ coactivator-1α is a central negative regulator of vascular senescence S Xiong, G Salazar, N Patrushev, M Ma, F Forouzandeh, L Hilenski, ... Arteriosclerosis, Thrombosis, and vascular biology 33 (5), 988-998, 2013 | 83 | 2013 |
| Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-α-dependent Akt activation in endosomes RR Nazarewicz, G Salazar, N Patrushev, A San Martin, L Hilenski, ... Journal of biological chemistry 286 (4), 2886-2895, 2011 | 69 | 2011 |
| Gene amplification and associated loss of 5′ regulatory sequences of CoAA in human cancers Y Sui, Z Yang, S Xiong, L Zhang, KL Blanchard, SC Peiper, WS Dynan, ... Oncogene 26 (6), 822-835, 2007 | 65 | 2007 |
| Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants L Zhang, S Dutta, S Xiong, M Chan, KK Chan, TM Fan, KL Bailey, ... Nature Chemical Biology 18 (3), 342-351, 2022 | 62 | 2022 |
| Alveolar stretch activation of endothelial Piezo1 protects adherens junctions and lung vascular barrier M Zhong, W Wu, H Kang, Z Hong, S Xiong, X Gao, J Rehman, ... American journal of respiratory cell and molecular biology 62 (2), 168-177, 2020 | 50 | 2020 |
| hSef potentiates EGF-mediated MAPK signaling through affecting EGFR trafficking and degradation Y Ren, L Cheng, Z Rong, Z Li, Y Li, X Zhang, S Xiong, J Hu, XY Fu, ... Cellular signalling 20 (3), 518-533, 2008 | 38 | 2008 |
| Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation Z Yang, Y Sui, S Xiong, SS Liour, AC Phillips, L Ko Nucleic acids research 35 (6), 1919-1932, 2007 | 35 | 2007 |
| Sef-S, an alternative splice isoform of sef gene, inhibits NIH3T3 cell proliferation via a mitogen-activated protein kinases p42 and p44 (ERK1/2)-independent mechanism Z Rong, Y Ren, L Cheng, Z Li, Y Li, Y Sun, H Li, S Xiong, Z Chang Cellular signalling 19 (1), 93-102, 2007 | 26 | 2007 |
| Interleukin-1RA mitigates SARS-CoV-2–induced inflammatory lung vascular leakage and mortality in humanized K18-hACE-2 mice S Xiong, L Zhang, AS Qadir, JM Richner, J Class, J Rehman, AB Malik Arteriosclerosis, thrombosis, and vascular biology 41 (11), 2773-2785, 2021 | 19 | 2021 |
Asrar B. MalikSchweppe Professor of Pharmacology and Head of Department, University ofVerified email at uic.edu
