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David M. Kern
David M. Kern
Senior Scientist, ModeX Therapeutics
Email verificata su modextx.com
Titolo
Citata da
Citata da
Anno
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs
DM Kern, B Sorum, SS Mali, CM Hoel, S Sridharan, JP Remis, DB Toso, ...
Nature structural & molecular biology 28 (7), 573-582, 2021
298*2021
Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
DM Kern, SC Oh, RK Hite, SG Brohawn
Elife 8, e42636, 2019
1002019
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
N Schweizer, C Ferrás, DM Kern, E Logarinho, IM Cheeseman, H Maiato
Journal of Cell Biology 203 (6), 883-893, 2013
802013
Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program
P Thiru, DM Kern, KL McKinley, JK Monda, F Rago, KC Su, T Tsinman, ...
Molecular biology of the cell 25 (13), 1983-1994, 2014
592014
Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80
DM Kern, JK Monda, KC Su, EM Wilson-Kubalek, IM Cheeseman
Elife 6, e26866, 2017
472017
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs
MS Reid, DM Kern, SG Brohawn
Elife 9, e52505, 2020
442020
Structure of SARS-CoV-2 M protein in lipid nanodiscs
KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth, SG Brohawn
Elife 11, e81702, 2022
412022
A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends
DM Kern, PK Nicholls, DC Page, IM Cheeseman
Journal of Cell Biology 213 (3), 315-328, 2016
372016
Ectopic activation of the spindle assembly checkpoint signaling cascade reveals its biochemical design
C Chen, IP Whitney, A Banerjee, C Sacristan, P Sekhri, DM Kern, ...
Current Biology 29 (1), 104-119. e10, 2019
212019
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes
SK Gunasekar, L Xie, A Kumar, J Hong, PR Chheda, C Kang, DM Kern, ...
Nature communications 13 (1), 784, 2022
192022
Structural basis for assembly and lipid-mediated gating of LRRC8A: C volume-regulated anion channels
DM Kern, J Bleier, S Mukherjee, JM Hill, AA Kossiakoff, EY Isacoff, ...
Nature Structural & Molecular Biology 30 (6), 841-852, 2023
142023
The outer kinetochore protein KNL-1 contains a defined oligomerization domain in nematodes
DM Kern, T Kim, M Rigney, N Hattersley, A Desai, IM Cheeseman
Molecular Biology of the Cell 26 (2), 229-237, 2015
102015
A rapid, inexpensive, and semi-quantitative method for determining pollen tube extension using fluorescence
E Hartman, C Levy, DM Kern, MA Johnson, A Basu
Plant Methods 10, 1-6, 2014
82014
Kinetochore structure: pulling answers from yeast
DM Kern, IM Cheeseman
Current biology 22 (19), R842-R844, 2012
42012
SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs
DM Kern, SG Brohawn
Methods in Enzymology 653, 207-235, 2021
12021
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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