Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors E Cartier, PJ Hamilton, AN Belovich, A Shekar, NG Campbell, C Saunders, ... EBioMedicine 2 (2), 135-146, 2015 | 77 | 2015 |
Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3 NG Campbell, A Shekar, JI Aguilar, D Peng, V Navratna, D Yang, ... Proceedings of the National Academy of Sciences 116 (9), 3853-3862, 2019 | 40 | 2019 |
Zn2+ reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder PJ Hamilton, A Shekar, AN Belovich, NB Christianson, NG Campbell, ... Molecular autism 6, 1-3, 2015 | 28 | 2015 |
A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster AN Belovich, JI Aguilar, SJ Mabry, MH Cheng, D Zanella, PJ Hamilton, ... Molecular psychiatry 26 (8), 4417-4430, 2021 | 25 | 2021 |
Atypical dopamine efflux caused by 3, 4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter A Shekar, JI Aguilar, G Galli, NV Cozzi, SD Brandt, AE Ruoho, ... Journal of chemical neuroanatomy 83, 69-74, 2017 | 21 | 2017 |
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease F Herborg, KL Jensen, S Tolstoy, NV Arends, LP Posselt, A Shekar, ... JCI insight 6 (18), 2021 | 10 | 2021 |
Syntaxin 1 Ser14 phosphorylation is required for nonvesicular dopamine release A Shekar, SJ Mabry, MH Cheng, JI Aguilar, S Patel, D Zanella, ... Science Advances 9 (2), eadd8417, 2023 | 4 | 2023 |
A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease F Herborg, KL Jensen, S Tolstoy, NV Arends, LP Posselt, A Shekar, ... bioRxiv, 2020.10. 12.336461, 2020 | | 2020 |
Genetic and Regulatory Disruptions Impacting Dopamine Transporter Function Contribute to Neuropsychiatric Disease Phenotypes A Shekar | | 2019 |
A rare, autism‐associated in‐frame deletion in the dopamine transporter exhibits profound functional deficits A Shekar, N Campbell, J Aguilar, D Peng, K Erreger, H Matthies, ... The FASEB Journal 32, 680.5-680.5, 2018 | | 2018 |
Phosphatidylinositol (4, 5)‐bisphosphate coordinates functional interactions in the dopamine transporter to promote amphetamine behaviors J Aguilar, A Shekar, H Matthies, A Galli The FASEB Journal 32, 541.11-541.11, 2018 | | 2018 |
human dopamine transporter A Shekar, JI Aguilar, G Galli, NV Cozzi, SD Brandt, AE Ruoho, ... | | |