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Aparna Shekar
Aparna Shekar
Graduate Student, Vanderbilt University
Verified email at vanderbilt.edu
Title
Cited by
Cited by
Year
Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors
E Cartier, PJ Hamilton, AN Belovich, A Shekar, NG Campbell, C Saunders, ...
EBioMedicine 2 (2), 135-146, 2015
772015
Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3
NG Campbell, A Shekar, JI Aguilar, D Peng, V Navratna, D Yang, ...
Proceedings of the National Academy of Sciences 116 (9), 3853-3862, 2019
402019
Zn2+ reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder
PJ Hamilton, A Shekar, AN Belovich, NB Christianson, NG Campbell, ...
Molecular autism 6, 1-3, 2015
282015
A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster
AN Belovich, JI Aguilar, SJ Mabry, MH Cheng, D Zanella, PJ Hamilton, ...
Molecular psychiatry 26 (8), 4417-4430, 2021
252021
Atypical dopamine efflux caused by 3, 4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter
A Shekar, JI Aguilar, G Galli, NV Cozzi, SD Brandt, AE Ruoho, ...
Journal of chemical neuroanatomy 83, 69-74, 2017
212017
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease
F Herborg, KL Jensen, S Tolstoy, NV Arends, LP Posselt, A Shekar, ...
JCI insight 6 (18), 2021
102021
Syntaxin 1 Ser14 phosphorylation is required for nonvesicular dopamine release
A Shekar, SJ Mabry, MH Cheng, JI Aguilar, S Patel, D Zanella, ...
Science Advances 9 (2), eadd8417, 2023
42023
A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease
F Herborg, KL Jensen, S Tolstoy, NV Arends, LP Posselt, A Shekar, ...
bioRxiv, 2020.10. 12.336461, 2020
2020
Genetic and Regulatory Disruptions Impacting Dopamine Transporter Function Contribute to Neuropsychiatric Disease Phenotypes
A Shekar
2019
A rare, autism‐associated in‐frame deletion in the dopamine transporter exhibits profound functional deficits
A Shekar, N Campbell, J Aguilar, D Peng, K Erreger, H Matthies, ...
The FASEB Journal 32, 680.5-680.5, 2018
2018
Phosphatidylinositol (4, 5)‐bisphosphate coordinates functional interactions in the dopamine transporter to promote amphetamine behaviors
J Aguilar, A Shekar, H Matthies, A Galli
The FASEB Journal 32, 541.11-541.11, 2018
2018
human dopamine transporter
A Shekar, JI Aguilar, G Galli, NV Cozzi, SD Brandt, AE Ruoho, ...
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