Paulo Fontoura
Paulo Fontoura
Global Head of Neuroscience, Roche Pharmaceuticals
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Citata da
Citata da
Ocrelizumab versus placebo in primary progressive multiple sclerosis
X Montalban, SL Hauser, L Kappos, DL Arnold, A Bar-Or, G Comi, ...
New England Journal of Medicine 376 (3), 209-220, 2017
Ocrelizumab versus interferon beta-1a in relapsing multiple sclerosis
SL Hauser, A Bar-Or, G Comi, G Giovannoni, HP Hartung, B Hemmer, ...
New England Journal of Medicine 376 (3), 221-234, 2017
The Parkinson progression marker initiative (PPMI)
K Marek, D Jennings, S Lasch, A Siderowf, C Tanner, T Simuni, C Coffey, ...
Progress in neurobiology 95 (4), 629-635, 2011
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
M Platten, PP Ho, S Youssef, P Fontoura, H Garren, EM Hur, R Gupta, ...
Science 310 (5749), 850-855, 2005
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
NA Naryshkin, M Weetall, A Dakka, J Narasimhan, X Zhao, Z Feng, ...
science 345 (6197), 688-693, 2014
The Global Adherence Project (GAP): A multicenter observational study on adherence to disease‐modifying therapies in patients with relapsing‐remitting multiple sclerosis
V Devonshire, Y Lapierre, R Macdonell, C Ramo‐Tello, F Patti, ...
European Journal of Neurology 18 (1), 69-77, 2011
A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease
S Ostrowitzki, RA Lasser, E Dorflinger, P Scheltens, F Barkhof, ...
Alzheimer's research & therapy 9 (1), 1-15, 2017
Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation
A Chora, P Fontoura, A Cunha, TF Pais, S Cardoso, PP Ho, LY Lee, ...
The Journal of clinical investigation 117 (2), 438-447, 2007
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
WH Robinson, P Fontoura, BJ Lee, HEN De Vegvar, J Tom, R Pedotti, ...
Nature biotechnology 21 (9), 1033-1039, 2003
Clinical and demographic predictors of long-term disability in patients with relapsing-remitting multiple sclerosis: a systematic review
A Langer-Gould, RA Popat, SM Huang, K Cobb, P Fontoura, MK Gould, ...
Archives of neurology 63 (12), 1686-1691, 2006
Risdiplam in type 1 spinal muscular atrophy
G Baranello, BT Darras, JW Day, N Deconinck, A Klein, R Masson, ...
New England Journal of Medicine 384 (10), 915-923, 2021
Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway
H Garren, PJ Ruiz, TA Watkins, P Fontoura, LVT Nguyen, ER Estline, ...
Immunity 15 (1), 15-22, 2001
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
R Pedotti, JJ DeVoss, S Youssef, D Mitchell, J Wedemeyer, R Madanat, ...
Proceedings of the National Academy of Sciences 100 (4), 1867-1872, 2003
Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects
C Sievers, M Meira, F Hoffmann, P Fontoura, L Kappos, RLP Lindberg
Clinical immunology 144 (1), 70-79, 2012
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease
S Salloway, M Farlow, E McDade, DB Clifford, G Wang, JJ Llibre-Guerra, ...
Nature medicine 27 (7), 1187-1196, 2021
Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer’s disease: a PET substudy interim analysis
G Klein, P Delmar, N Voyle, S Rehal, C Hofmann, D Abi-Saab, ...
Alzheimer's research & therapy 11 (1), 1-12, 2019
An immunomodulatory GpG oligonucleotide for the treatment of autoimmunity via the innate and adaptive immune systems
PP Ho, P Fontoura, PJ Ruiz, L Steinman, H Garren
The Journal of Immunology 171 (9), 4920-4926, 2003
Safety and efficacy of olesoxime in patients with type 2 or non-ambulatory type 3 spinal muscular atrophy: a randomised, double-blind, placebo-controlled phase 2 trial
E Bertini, E Dessaud, E Mercuri, F Muntoni, J Kirschner, C Reid, ...
The Lancet Neurology 16 (7), 513-522, 2017
Drug discovery for autism spectrum disorder: challenges and opportunities
A Ghosh, A Michalon, L Lindemann, P Fontoura, L Santarelli
Nature reviews Drug discovery 12 (10), 777-790, 2013
Efficacy and safety of basimglurant as adjunctive therapy for major depression: a randomized clinical trial
JA Quiroz, P Tamburri, D Deptula, L Banken, U Beyer, M Rabbia, ...
JAMA psychiatry 73 (7), 675-684, 2016
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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