Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, ... Nature communications 9 (1), 335, 2018 | 249 | 2018 |
A critical role of autophagy in regulating microglia polarization in neurodegeneration M Jin, F Wang, DI Qi, W Liu, C Gu, CJ Mao, YP Yang, Z Zhao, LF Hu, ... Frontiers in Aging Neuroscience 10, 378, 2018 | 134 | 2018 |
CaMKKβ-dependent activation of AMP-activated protein kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation X Zhou, Y Cao, G Ao, L Hu, H Liu, J Wu, X Wang, M Jin, S Zheng, X Zhen, ... Antioxidants & redox signaling 21 (12), 1741-1758, 2014 | 130 | 2014 |
Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology R Xu, AJ Boreland, X Li, C Erickson, M Jin, C Atkins, ZP Pang, BP Daniels, ... Stem cell reports 16 (8), 1923-1937, 2021 | 129 | 2021 |
Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis M Jin, R Günther, K Akgün, A Hermann, T Ziemssen Scientific reports 10 (1), 5941, 2020 | 84 | 2020 |
A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation JD Wang, YL Cao, Q Li, YP Yang, M Jin, D Chen, F Wang, GH Wang, ... Autophagy 11 (11), 2057-2073, 2015 | 79 | 2015 |
TNF compromises lysosome acidification and reduces α-synuclein degradation via autophagy in dopaminergic cells MX Wang, XY Cheng, M Jin, YL Cao, YP Yang, JD Wang, Q Li, F Wang, ... Experimental neurology 271, 112-121, 2015 | 56 | 2015 |
Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease M Jin, R Xu, L Wang, MM Alam, Z Ma, S Zhu, AC Martini, A Jadali, ... Cell Stem Cell 29 (7), 1135-1153. e8, 2022 | 54 | 2022 |
Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type C Du, M Jin, Y Hong, Q Li, XH Wang, JM Xu, F Wang, Y Zhang, J Jia, ... Biochemical and Biophysical Research Communications 451 (2), 239-245, 2014 | 53 | 2014 |
Interleukin-17 and Th17 lymphocytes directly impair motoneuron survival of wildtype and FUS-ALS mutant human iPSCs M Jin, K Akgün, T Ziemssen, M Kipp, R Günther, A Hermann International Journal of Molecular Sciences 22 (15), 8042, 2021 | 22 | 2021 |
Generation of iPSC-based human-mouse microglial brain chimeras to study senescence of human microglia M Jin, Z Ma, P Jiang STAR Protocols 3 (4), 101847, 2022 | 5 | 2022 |
Replacing microglia to treat Alzheimer’s disease P Jiang, M Jin Cell stem cell 30 (8), 1001-1003, 2023 | 3 | 2023 |
Rag2−/− accelerates lipofuscin accumulation in the brain: Implications for human stem cell brain transplantation studies M Jin, MM Alam, AYC Liu, P Jiang Stem Cell Reports 17 (11), 2381-2391, 2022 | 2 | 2022 |
A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimers Disease M Jin, Z Ma, R Dang, H Zhang, H Xue, J Pascual, S Finkbeiner, E Head, ... bioRxiv, 2024.03. 12.584646, 2024 | | 2024 |
Rag2−/− accelerates lipofuscin accumulation in the brain: Implications for human stem cell brain transplantation studies M Jin, MM Alam, AYC Liu, P Jiang Stem Cell Reports 18 (1), 413-415, 2023 | | 2023 |