| Endothelial-to-mesenchymal transition contributes to cardiac fibrosis EM Zeisberg, O Tarnavski, M Zeisberg, AL Dorfman, JR McMullen, ... Nature medicine 13 (8), 952-961, 2007 | 2472 | 2007 |
| Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies BC Bernardo, KL Weeks, L Pretorius, JR McMullen Pharmacology & therapeutics 128 (1), 191-227, 2010 | 1146 | 2010 |
| Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets YK Tham, BC Bernardo, JYY Ooi, KL Weeks, JR McMullen Archives of toxicology 89, 1401-1438, 2015 | 738 | 2015 |
| Phosphoinositide 3-kinase (p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy JR McMullen, T Shioi, L Zhang, O Tarnavski, MC Sherwood, PM Kang, ... Proceedings of the National Academy of Sciences 100 (21), 12355-12360, 2003 | 698 | 2003 |
| Akt/protein kinase B promotes organ growth in transgenic mice T Shioi, JR McMullen, PM Kang, PS Douglas, T Obata, TF Franke, ... Molecular and cellular biology 22 (8), 2799-2809, 2002 | 626 | 2002 |
| Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways K Huynh, BC Bernardo, JR McMullen, RH Ritchie Pharmacology & therapeutics 142 (3), 375-415, 2014 | 620 | 2014 |
| Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure. JR McMullen, GL Jennings Clinical & Experimental Pharmacology & Physiology 34 (4), 2007 | 578 | 2007 |
| Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload JR McMullen, MC Sherwood, O Tarnavski, L Zhang, AL Dorfman, T Shioi, ... Circulation 109 (24), 3050-3055, 2004 | 563 | 2004 |
| Rapamycin attenuates load-induced cardiac hypertrophy in mice T Shioi, JR McMullen, O Tarnavski, K Converso, MC Sherwood, ... Circulation 107 (12), 1664-1670, 2003 | 536 | 2003 |
| The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase (p110α) pathway JR McMullen, T Shioi, WY Huang, L Zhang, O Tarnavski, E Bisping, ... Journal of Biological Chemistry 279 (6), 4782-4793, 2004 | 522 | 2004 |
| Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function BC Bernardo, XM Gao, CE Winbanks, EJH Boey, YK Tham, H Kiriazis, ... Proceedings of the National Academy of Sciences 109 (43), 17615-17620, 2012 | 474 | 2012 |
| Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies O Tarnavski, JR McMullen, M Schinke, Q Nie, S Kong, S Izumo Physiological genomics 16 (3), 349-360, 2004 | 458 | 2004 |
| Ibrutinib increases the risk of atrial fibrillation, potentially through inhibition of cardiac PI3K-Akt signaling JR McMullen, EJH Boey, JYY Ooi, JF Seymour, MJ Keating, CS Tam Blood, The Journal of the American Society of Hematology 124 (25), 3829-3830, 2014 | 373 | 2014 |
| Protective effects of exercise and phosphoinositide 3-kinase (p110α) signaling in dilated and hypertrophic cardiomyopathy JR McMullen, F Amirahmadi, EA Woodcock, M Schinke-Braun, ... Proceedings of the National Academy of Sciences 104 (2), 612-617, 2007 | 358 | 2007 |
| miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart BC Bernardo, JYY Ooi, RCY Lin, JR McMullen Future medicinal chemistry 7 (13), 1771-1792, 2015 | 265 | 2015 |
| Class IA Phosphoinositide 3-Kinase Regulates Heart Size and Physiological Cardiac Hypertrophy J Luo, JR McMullen, CL Sobkiw, L Zhang, AL Dorfman, MC Sherwood, ... Molecular and cellular biology 25 (21), 9491-9502, 2005 | 256 | 2005 |
| The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes? KL Weeks, JR McMullen Physiology 26 (2), 97-105, 2011 | 243 | 2011 |
| Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin CE Winbanks, KL Weeks, RE Thomson, PV Sepulveda, C Beyer, H Qian, ... Journal of Cell Biology 197 (7), 997-1008, 2012 | 230 | 2012 |
| Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure E Bisping, S Ikeda, SW Kong, O Tarnavski, N Bodyak, JR McMullen, ... Proceedings of the National Academy of Sciences 103 (39), 14471-14476, 2006 | 230 | 2006 |
| The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass CE Winbanks, JL Chen, H Qian, Y Liu, BC Bernardo, C Beyer, KI Watt, ... Journal of Cell Biology 203 (2), 345-357, 2013 | 215 | 2013 |
