Steven H. Kleinstein
Steven H. Kleinstein
Professor, Departments of Pathology and Immunobiology, Yale School of Medicine
Verified email at - Homepage
Cited by
Cited by
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
Two levels of protection for the B cell genome during somatic hypermutation
M Liu, JL Duke, DJ Richter, CG Vinuesa, CC Goodnow, SH Kleinstein, ...
Nature 451 (7180), 841-845, 2008
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone
SM Kerfoot, G Yaari, JR Patel, KL Johnson, DG Gonzalez, SH Kleinstein, ...
Immunity 34 (6), 947-960, 2011
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns
AE Hauser, T Junt, TR Mempel, MW Sneddon, SH Kleinstein, ...
Immunity 26 (5), 655-667, 2007
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ...
Science translational medicine 6 (248), 248ra107-248ra107, 2014
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4+ cell properties during viral infection
HD Marshall, A Chandele, YW Jung, H Meng, AC Poholek, IA Parish, ...
Immunity 35 (4), 633-646, 2011
CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype
GV Zuccarino-Catania, S Sadanand, FJ Weisel, MM Tomayko, H Meng, ...
Nature immunology 15 (7), 631-637, 2014
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ...
Bioinformatics 31 (20), 3356-3358, 2015
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’Connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells
VM Bruno, S Hannemann, M Lara-Tejero, RA Flavell, SH Kleinstein, ...
PLoS Pathog 5 (8), e1000538, 2009
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
K Bryniarski, W Ptak, A Jayakumar, K Püllmann, MJ Caplan, ...
Journal of allergy and clinical immunology 132 (1), 170-181. e9, 2013
Practical guidelines for B-cell receptor repertoire sequencing analysis
G Yaari, SH Kleinstein
Genome medicine 7 (1), 121, 2015
Quantifying selection in high-throughput Immunoglobulin sequencing data sets
G Yaari, M Uduman, SH Kleinstein
Nucleic acids research 40 (17), e134-e134, 2012
High-resolution antibody dynamics of vaccine-induced immune responses
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells
SC Eisenbarth, A Williams, OR Colegio, H Meng, T Strowig, A Rongvaux, ...
Nature 484 (7395), 510-513, 2012
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
BJ Laidlaw, W Cui, RA Amezquita, SM Gray, T Guan, Y Lu, Y Kobayashi, ...
Nature immunology 16 (8), 871, 2015
Dynamic expression profiling of type I and type III interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression
CR Bolen, S Ding, MD Robek, SH Kleinstein
Hepatology 59 (4), 1262-1272, 2014
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
G Yaari, J Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
Simulating the immune system
SH Kleinstein, PE Seiden
Computing in Science & Engineering 2 (4), 69-77, 2000
Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles
D Gadala-Maria, G Yaari, M Uduman, SH Kleinstein
Proceedings of the National Academy of Sciences 112 (8), E862-E870, 2015
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