Anton Simeonov
Citata da
Citata da
Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19
RT Eastman, JS Roth, KR Brimacombe, A Simeonov, M Shen, S Patnaik, ...
ACS central Science 6 (5), 672-683, 2020
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries
J Inglese, DS Auld, A Jadhav, RL Johnson, A Simeonov, A Yasgar, ...
Proceedings of the National Academy of Sciences 103 (31), 11473-11478, 2006
High-throughput screening assays for the identification of chemical probes
J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld
Nature chemical biology 3 (8), 466-479, 2007
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
SAI Seidel, PM Dijkman, WA Lea, G van den Bogaart, ...
Methods 59 (3), 301-315, 2013
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
Fluorescence polarization assays in small molecule screening
WA Lea, A Simeonov
Expert opinion on drug discovery 6 (1), 17-32, 2011
A high-throughput screen for aggregation-based inhibition in a large compound library
BY Feng, A Simeonov, A Jadhav, K Babaoglu, J Inglese, BK Shoichet, ...
Journal of medicinal chemistry 50 (10), 2385-2390, 2007
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
LA Mathews Griner, R Guha, P Shinn, RM Young, JM Keller, D Liu, ...
Proceedings of the National Academy of Sciences 111 (6), 2349-2354, 2014
Gene expression analysis identifies global gene dosage sensitivity in cancer
RSN Fehrmann, JM Karjalainen, M Krajewska, HJ Westra, D Maloney, ...
Nature genetics 47 (2), 115-125, 2015
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317-332, 2018
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ...
Nature communications 4 (1), 2035, 2013
Identification of oxadiazoles as new drug leads for the control of schistosomiasis
AA Sayed, A Simeonov, CJ Thomas, J Inglese, CP Austin, DL Williams
Nature medicine 14 (4), 407-412, 2008
Fluorescence spectroscopic profiling of compound libraries
A Simeonov, A Jadhav, CJ Thomas, Y Wang, R Huang, NT Southall, ...
Journal of medicinal chemistry 51 (8), 2363-2371, 2008
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors
RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ...
Journal of medicinal chemistry 53 (13), 4891-4905, 2010
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease
A Jadhav, RS Ferreira, C Klumpp, BT Mott, CP Austin, J Inglese, ...
Journal of medicinal chemistry 53 (1), 37-51, 2010
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ...
Journal of medicinal chemistry 52 (24), 7950-7953, 2009
The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality
MS Attene-Ramos, N Miller, R Huang, S Michael, M Itkin, RJ Kavlock, ...
Drug discovery today 18 (15-16), 716-723, 2013
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses
JM Jaynes, R Sable, M Ronzetti, W Bautista, Z Knotts, ...
Science translational medicine 12 (530), eaax6337, 2020
A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
Q Liang, TS Dexheimer, P Zhang, AS Rosenthal, MA Villamil, C You, ...
Nature chemical biology 10 (4), 298-304, 2014
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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