| Target identification among known drugs by deep learning from heterogeneous networks X Zeng, S Zhu, W Lu, Z Liu, J Huang, Y Zhou, J Fang, Y Huang, H Guo, ... Chemical Science 11 (7), 1775-1797, 2020 | 240 | 2020 |
| A genome-wide positioning systems network algorithm for in silico drug repurposing F Cheng, W Lu, C Liu, J Fang, Y Hou, DE Handy, R Wang, Y Zhao, ... Nature communications 10 (1), 3476, 2019 | 162 | 2019 |
| Deep learning-based prediction of drug-induced cardiotoxicity C Cai, P Guo, Y Zhou, J Zhou, Q Wang, F Zhang, J Fang, F Cheng Journal of chemical information and modeling 59 (3), 1073-1084, 2019 | 156 | 2019 |
| In silico polypharmacology of natural products J Fang, C Liu, Q Wang, P Lin, F Cheng Briefings in bioinformatics 19 (6), 1153-1171, 2018 | 149 | 2018 |
| Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ... Nature genetics 53 (3), 342-353, 2021 | 131 | 2021 |
| Discovery of multitarget-directed ligands against Alzheimer’s disease through systematic prediction of chemical–protein interactions J Fang, Y Li, R Liu, X Pang, C Li, R Yang, Y He, W Lian, AL Liu, GH Du Journal of chemical information and modeling 55 (1), 149-164, 2015 | 122 | 2015 |
| Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment J Fang, L Wang, T Wu, C Yang, L Gao, H Cai, J Liu, S Fang, Y Chen, ... Journal of ethnopharmacology 196, 281-292, 2017 | 116 | 2017 |
| Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou, S Stauffer, L Li, ... Nature Aging 1 (12), 1175-1188, 2021 | 111 | 2021 |
| Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation L Gao, K Wang, Y Zhou, J Fang, X Qin, G Du Scientific reports 8 (1), 624, 2018 | 105 | 2018 |
| Predictions of BuChE inhibitors using support vector machine and naive Bayesian classification techniques in drug discovery J Fang, R Yang, L Gao, D Zhou, S Yang, A Liu, G Du Journal of chemical information and modeling 53 (11), 3009-3020, 2013 | 100 | 2013 |
| Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug–Target Interactions of Natural Products Enables New Targeted Cancer Therapy J Fang, Z Wu, C Cai, Q Wang, Y Tang, F Cheng Journal of chemical information and modeling 57 (11), 2657-2671, 2017 | 78 | 2017 |
| Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulation J Fang, P Wu, R Yang, L Gao, C Li, D Wang, S Wu, AL Liu, GH Du Acta Pharmaceutica Sinica B 4 (6), 430-437, 2014 | 77 | 2014 |
| Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing J Fang, AA Pieper, R Nussinov, G Lee, L Bekris, JB Leverenz, ... Medicinal research reviews 40 (6), 2386-2426, 2020 | 62 | 2020 |
| A systems pharmacology approach uncovers wogonoside as an angiogenesis inhibitor of triple-negative breast cancer by targeting hedgehog signaling Y Huang, J Fang, W Lu, Z Wang, Q Wang, Y Hou, X Jiang, O Reizes, ... Cell chemical biology 26 (8), 1143-1158. e6, 2019 | 62 | 2019 |
| DeepScreening: a deep learning-based screening web server for accelerating drug discovery Z Liu, J Du, J Fang, Y Yin, G Xu, L Xie Database 2019, baz104, 2019 | 60 | 2019 |
| Quercetin ameliorates diabetic encephalopathy through SIRT1/ER stress pathway in db/db mice T Hu, JJ Shi, J Fang, Q Wang, YB Chen, SJ Zhang Aging (Albany NY) 12 (8), 7015, 2020 | 56 | 2020 |
| Berberine Improves Diabetic Encephalopathy Through the SIRT1/ER Stress Pathway in db/db Mice HY Li, XC Wang, YM Xu, NC Luo, S Luo, XY Hao, SY Cheng, JS Fang, ... Rejuvenation Research 21 (3), 200-209, 2018 | 55 | 2018 |
| Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease P Xiao-Cong, K De, F Jian-Song, Z Ying, XU Lv-Jie, L Wen-Wen, ... Chinese Journal of Natural Medicines 16 (1), 53-62, 2018 | 55 | 2018 |
| Ameliorative effects of baicalein in MPTP-induced mouse model of Parkinson's disease: a microarray study L Gao, C Li, RY Yang, WW Lian, JS Fang, XC Pang, XM Qin, AL Liu, ... Pharmacology Biochemistry and Behavior 133, 155-163, 2015 | 54 | 2015 |
| The mechanisms of Bushen-Yizhi formula as a therapeutic agent against Alzheimer’s disease H Cai, Y Luo, X Yan, P Ding, Y Huang, S Fang, R Zhang, Y Chen, Z Guo, ... Scientific Reports 8 (1), 3104, 2018 | 52 | 2018 |
Feixiong ChengCleveland ClinicEmail verificata su ccf.org
