Bas Boukens
Bas Boukens
Assistant Professor
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Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
CR Bezzina, J Barc, Y Mizusawa, CA Remme, JB Gourraud, F Simonet, ...
Nature genetics 45 (9), 1044-1049, 2013
Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system
ML Bakker, BJ Boukens, MTM Mommersteeg, JF Brons, V Wakker, ...
Circulation research 102 (11), 1340-1349, 2008
Identification and functional characterization of cardiac pacemaker cells in zebrafish
F Tessadori, JH van Weerd, SB Burkhard, AO Verkerk, E de Pater, ...
Public Library of Science 7 (10), e47644, 2012
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells
ML Bakker, GJJ Boink, BJ Boukens, AO Verkerk, M van den Boogaard, ...
Cardiovascular research 94 (3), 439-449, 2012
Developmental basis for electrophysiological heterogeneity in the ventricular and outflow tract myocardium as a substrate for life-threatening ventricular arrhythmias
BJD Boukens, VM Christoffels, R Coronel, AFM Moorman
Circulation research 104 (1), 19-31, 2009
Misinterpretation of the mouse ECG: ‘musing the waves of Mus musculus
BJ Boukens, MR Rivaud, S Rentschler, R Coronel
The Journal of physiology 592 (21), 4613-4626, 2014
Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm
RD Nadadur, MT Broman, B Boukens, SR Mazurek, X Yang, ...
Science translational medicine 8 (354), 354ra115-354ra115, 2016
Identifying the evolutionary building blocks of the cardiac conduction system
B Jensen, BJD Boukens, AV Postma, QD Gunst, MJB van den Hoff, ...
Public Library of Science 7 (9), e44231, 2012
Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice
WTJ Aanhaanen, BJD Boukens, A Sizarov, V Wakker, C de Gier-de Vries, ...
The Journal of clinical investigation 121 (2), 534-544, 2011
Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties
BS Gillers, A Chiplunkar, H Aly, T Valenta, K Basler, VM Christoffels, ...
Circulation research 116 (3), 398-406, 2015
Reduced sodium channel function unmasks residual embryonic slow conduction in the adult right ventricular outflow tract
BJ Boukens, M Sylva, C de Gier-de Vries, CA Remme, CR Bezzina, ...
Circulation Research 113 (2), 137-141, 2013
Dietary fish oil reduces pacemaker current and heart rate in rabbit
AO Verkerk, HM den Ruijter, J Bourier, BJ Boukens, IA Brouwer, ...
Heart Rhythm 6 (10), 1485-1492, 2009
The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity
CC Veerman, S Podliesna, R Tadros, EM Lodder, I Mengarelli, ...
Circulation research 121 (5), 537-548, 2017
Identification of atrial fibrillation associated genes and functional non-coding variants
AF van Ouwerkerk, FM Bosada, K van Duijvenboden, MC Hill, ...
Nature communications 10 (1), 4755, 2019
ElectroMap: high-throughput open-source software for analysis and mapping of cardiac electrophysiology
C O’Shea, AP Holmes, TY Yu, J Winter, SP Wells, J Correia, BJ Boukens, ...
Scientific reports 9 (1), 1389, 2019
Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration
BJ Boukens, MG Hoogendijk, AO Verkerk, A Linnenbank, P van Dam, ...
Cardiovascular research 97 (1), 182-191, 2013
Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program
VWW Van Eif, S Stefanovic, K Van Duijvenboden, M Bakker, V Wakker, ...
Development 146 (8), dev173161, 2019
Transmural APD gradient synchronizes repolarization in the human left ventricular wall
BJ Boukens, MS Sulkin, CR Gloschat, FS Ng, EJ Vigmond, IR Efimov
Cardiovascular research 108 (1), 188-196, 2015
Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations
S Hamad, D Derichsweiler, S Papadopoulos, F Nguemo, T Šarić, ...
Theranostics 9 (24), 7222, 2019
The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi
JWR Hovius, MF Bijlsma, GJW van der Windt, WJ Wiersinga, ...
PLoS pathogens 5 (5), e1000447, 2009
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