| β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies M Bartolini, C Bertucci, V Cavrini, V Andrisano Biochemical pharmacology 65 (3), 407-416, 2003 | 676 | 2003 |
| Insight Into the Kinetic of Amyloid β (1–42) Peptide Self‐Aggregation: Elucidation of Inhibitors’ Mechanism of Action M Bartolini, C Bertucci, ML Bolognesi, A Cavalli, C Melchiorre, ... ChemBioChem 8 (17), 2152-2161, 2007 | 416 | 2007 |
| 3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β … L Piazzi, A Rampa, A Bisi, S Gobbi, F Belluti, A Cavalli, M Bartolini, ... Journal of medicinal chemistry 46 (12), 2279-2282, 2003 | 317 | 2003 |
| Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer’s disease ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ... Journal of medicinal chemistry 50 (26), 6446-6449, 2007 | 311 | 2007 |
| Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds L Piazzi, A Cavalli, F Colizzi, F Belluti, M Bartolini, F Mancini, ... Bioorganic & Medicinal Chemistry Letters 18 (1), 423-426, 2008 | 297 | 2008 |
| Rational approach to discover multipotent anti-Alzheimer drugs M Rosini, V Andrisano, M Bartolini, ML Bolognesi, P Hrelia, A Minarini, ... Journal of medicinal chemistry 48 (2), 360-363, 2005 | 292 | 2005 |
| Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease P Muñoz-Ruiz, L Rubio, E García-Palomero, I Dorronsoro, ... Journal of medicinal chemistry 48 (23), 7223-7233, 2005 | 251 | 2005 |
| Novel donepezil-based inhibitors of acetyl-and butyrylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation P Camps, X Formosa, C Galdeano, T Gómez, D Munoz-Torrero, ... Journal of medicinal chemistry 51 (12), 3588-3598, 2008 | 241 | 2008 |
| Inhibition of acetylcholinesterase, β-amyloid aggregation, and NMDA receptors in Alzheimer’s disease: a promising direction for the multi-target-directed ligands gold rush M Rosini, E Simoni, M Bartolini, A Cavalli, L Ceccarini, N Pascu, ... Journal of medicinal chemistry 51 (15), 4381-4384, 2008 | 236 | 2008 |
| A small molecule targeting the multifactorial nature of Alzheimer's disease A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46, 3689-3692, 2007 | 235 | 2007 |
| Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds P Camps, X Formosa, C Galdeano, D Munoz-Torrero, L Ramirez, ... Journal of medicinal chemistry 52 (17), 5365-5379, 2009 | 231 | 2009 |
| SAR of 9-amino-1, 2, 3, 4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues M Recanatini, A Cavalli, F Belluti, L Piazzi, A Rampa, A Bisi, S Gobbi, ... Journal of medicinal chemistry 43 (10), 2007-2018, 2000 | 219 | 2000 |
| Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, β amyloid aggregation, and Aβ neurotoxicity S Rizzo, C Rivière, L Piazzi, A Bisi, S Gobbi, M Bartolini, V Andrisano, ... Journal of medicinal chemistry 51 (10), 2883-2886, 2008 | 216 | 2008 |
| Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects E Nepovimova, E Uliassi, J Korabecny, LE Pena-Altamira, S Samez, ... Journal of medicinal chemistry 57 (20), 8576-8589, 2014 | 185 | 2014 |
| Tacripyrines, the first tacrine− dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer’s disease J Marco-Contelles, R León, C De Los Ríos, A Samadi, M Bartolini, ... Journal of medicinal chemistry 52 (9), 2724-2732, 2009 | 174 | 2009 |
| Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ... Journal of medicinal chemistry 50 (20), 4882-4897, 2007 | 171 | 2007 |
| Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-β aggregation ML Bolognesi, V Andrisano, M Bartolini, R Banzi, C Melchiorre Journal of medicinal chemistry 48 (1), 24-27, 2005 | 166 | 2005 |
| Strategies for the inhibition of protein aggregation in human diseases M Bartolini, V Andrisano ChemBioChem 11 (8), 1018-1035, 2010 | 163 | 2010 |
| Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues ML Bolognesi, M Bartolini, A Cavalli, V Andrisano, M Rosini, A Minarini, ... Journal of medicinal chemistry 47 (24), 5945-5952, 2004 | 161 | 2004 |
| Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents E Viayna, I Sola, M Bartolini, A De Simone, C Tapia-Rojas, FG Serrano, ... Journal of Medicinal Chemistry 57 (6), 2549-2567, 2014 | 152 | 2014 |
