Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease RB DeMattos, KR Bales, DJ Cummins, JC Dodart, SM Paul, DM Holtzman Proceedings of the National Academy of Sciences 98 (15), 8850-8855, 2001 | 1743 | 2001 |
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition KR Bales, T Verina, RC Dodel, Y Du, L Altstiel, M Bender, P Hyslop, ... Nature genetics 17 (3), 263-264, 1997 | 1080 | 1997 |
Brain to plasma amyloid-β efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease RB DeMattos, KR Bales, DJ Cummins, SM Paul, DM Holtzman science 295 (5563), 2264-2267, 2002 | 745 | 2002 |
Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease KR Bales, T Verina, DJ Cummins, Y Du, RC Dodel, J Saura, CE Fishman, ... Proceedings of the National Academy of Sciences 96 (26), 15233-15238, 1999 | 636 | 1999 |
Neuroinflammation‐induced acceleration of amyloid deposition in the APPV717F transgenic mouse X Qiao, DJ Cummins, SM Paul European Journal of Neuroscience 14 (3), 474-482, 2001 | 153 | 2001 |
Molecular diversity in chemical databases: comparison of medicinal chemistry knowledge bases and databases of commercially available compounds DJ Cummins, CW Andrews, JA Bentley, M Cory Journal of Chemical Information and Computer Sciences 36 (4), 750-763, 1996 | 152 | 1996 |
Iteratively reweighted partial least squares: a performance analysis by Monte Carlo simulation DJ Cummins, CW Andrews Journal of Chemometrics 9 (6), 489-507, 1995 | 129 | 1995 |
DoMCoSAR: A Novel Approach for Establishing the Docking Mode That Is Consistent with the Structure− Activity Relationship. Application to HIV-1 Protease Inhibitors and VEGF … M Vieth, DJ Cummins Journal of medicinal chemistry 43 (16), 3020-3032, 2000 | 100 | 2000 |
Confidence intervals for nonparametric curve estimates: Toward more uniform pointwise coverage DJ Cummins, TG Filloon, D Nychka Journal of the American Statistical Association 96 (453), 233-246, 2001 | 83 | 2001 |
Assay method for alzheimer's disease DM Holtzman, R DeMattos, KR Bales, DJ Cummins, SM Paul US Patent 7,771,722, 2010 | 62 | 2010 |
Long-term effects of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate and 6-nitro-7-sulphamoylbenzo (f) quinoxaline-2, 3-dione in the rat basal ganglia: calcification, changes … V Petegnief, J Saura, D Dewar, DJ Cummins, M Dragunow, N Mahy Neuroscience 94 (1), 105-115, 1999 | 36 | 1999 |
Integrating everything: the molecule selection toolkit, a system for compound prioritization in drug discovery DJ Cummins, MA Bell Journal of medicinal chemistry 59 (15), 6999-7010, 2016 | 34 | 2016 |
Two-site evaluation of the repeatability and precision of an automated dual-column hydrogen/deuterium exchange mass spectrometry platform DJ Cummins, A Espada, SJ Novick, M Molina-Martin, RE Stites, ... Analytical chemistry 88 (12), 6607-6614, 2016 | 29 | 2016 |
Statistical aspects of quantitative image analysis of β-amyloid in the APPV717F transgenic mouse model of Alzheimer's disease CE Fishman, DJ Cummins, KR Bales, CA DeLong, MA Esterman, ... Journal of neuroscience methods 108 (2), 145-152, 2001 | 26 | 2001 |
Investigating the behavior of published PAINS alerts using a pharmaceutical company data set LR Vidler, IA Watson, BJ Margolis, DJ Cummins, M Brunavs ACS Medicinal Chemistry Letters 9 (8), 792-796, 2018 | 23 | 2018 |
Multiplex proteomic approaches to sepsis research: case studies employing new technologies JG Heuer, DJ Cummins, BT Edmonds Expert Review of Proteomics 2 (5), 669-680, 2005 | 18 | 2005 |
Assay method for Alzheimer's disease DM Holtzman, R DeMattos, KR Bales, DJ Cummins, SM Paul US Patent 8,444,977, 2013 | 12 | 2013 |
Selectivity data: assessment, predictions, concordance, and implications C Gao, S Cahya, CA Nicolaou, J Wang, IA Watson, DJ Cummins, ... Journal of Medicinal Chemistry 56 (17), 6991-7002, 2013 | 11 | 2013 |
An Alternative to 3D QSAR: Application of Genetic Algorithms and Partial Least Squares to Variable Selection of Topological Indices. Submitted for publication in SJ Cho, D Cummins, J Bentley, CW Andrews, A Tropsha J. Comput.-Aided Mol. Des, 1998 | 8 | 1998 |
Pharmaceutical drug discovery: designing the blockbuster drug DJ Cummins Screening: Methods for Experimentation in Industry, Drug Discovery, and …, 2006 | 7 | 2006 |