John Clapham
John Clapham
Pro Vice Chancellor Health Sciences and Research, University of Buckingham
Verified email at buckingham.ac.uk
Title
Cited by
Cited by
Year
Superoxide activates mitochondrial uncoupling proteins
KS Echtay, D Roussel, J St-Pierre, MB Jekabsons, S Cadenas, JA Stuart, ...
Nature 415 (6867), 96-99, 2002
14682002
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
JC Clapham, JRS Arch, H Chapman, A Haynes, C Lister, GBT Moore, ...
Nature 406 (6794), 415-418, 2000
6932000
Hypothalamic orexin expression: modulation by blood glucose and feeding.
XJ Cai, PS Widdowson, J Harrold, S Wilson, RE Buckingham, JR Arch, ...
Diabetes 48 (11), 2132-2137, 1999
3501999
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal …
PW Young, DR Buckle, BCC Cantello, H Chapman, JC Clapham, ...
Journal of Pharmacology and Experimental Therapeutics 284 (2), 751-759, 1998
3171998
Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats
RE Buckingham, KA Al-Barazanji, CDN Toseland, M Slaughter, ...
Diabetes 47 (8), 1326-1334, 1998
2681998
Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity
JR Speakman, DA Levitsky, DB Allison, MS Bray, JM De Castro, DJ Clegg, ...
Disease models & mechanisms 4 (6), 733-745, 2011
2452011
Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice
GBT Moore, H Chapman, JC Holder, CA Lister, V Piercy, SA Smith, ...
Biochemical and biophysical research communications 286 (4), 735-741, 2001
2392001
The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3
S Cadenas, KS Echtay, JA Harper, MB Jekabsons, JA Buckingham, ...
Journal of Biological Chemistry 277 (4), 2773-2778, 2002
2202002
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3
MD Brand, R Pamplona, M Portero-Otín, JR Requena, SJ Roebuck, ...
Biochemical Journal 368 (2), 597-603, 2002
2072002
Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice
AC Haynes, H Chapman, C Taylor, GBT Moore, MA Cawthorne, ...
Regulatory peptides 104 (1-3), 153-159, 2002
1682002
Anti-obesity drugs: a critical review of current therapies and future opportunities
JC Clapham, JRS Arch, M Tadayyon
Pharmacology & therapeutics 89 (1), 81-121, 2001
1422001
BRL 34915, a novel antihypertensive agent: comparison of effects on blood pressure and other haemodynamic parameters with those of nifedipine in animal models.
RE Buckingham, JC Clapham, TC Hamilton, SD Longman, J Norton, ...
Journal of cardiovascular pharmacology 8 (4), 798, 1986
1281986
Liver‐directed overexpression of mitochondrial glycerol‐3‐phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid …
D Lindén, L William‐Olsson, A Ahnmark, K Ekroos, C Hallberg, ...
The FASEB Journal 20 (3), 434-443, 2006
1182006
Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3β on a muscle-specific promoter
NJ Pearce, JRS Arch, JC Clapham, MP Coghlan, SL Corcoran, CA Lister, ...
Metabolism 53 (10), 1322-1330, 2004
1142004
Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
D Lindén, L William-Olsson, M Rhedin, AK Asztély, JC Clapham, ...
Journal of lipid research 45 (7), 1279-1288, 2004
992004
Central control of thermogenesis
JC Clapham
Neuropharmacology 63 (1), 111-123, 2012
962012
Insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment: current status and therapeutic possibilities
NC Turner, JC Clapham
Progress in drug research, 33-94, 1998
911998
DPP‐IV inhibition enhances the antilipolytic action of NPY in human adipose tissue
K Kos, AR Baker, M Jernas, AL Harte, JC Clapham, JP O’Hare, ...
Diabetes, Obesity and Metabolism 11 (4), 285-292, 2009
852009
The Thiazolidinedione Insulin Sensitiser, BRL 49653, Increases the Expression of PPAR-γ and aP2in Adipose Tissue of High-Fat-Fed Rats
SL Pearson, MA Cawthorne, JC Clapham, SJ Dunmore, SD Holmes, ...
Biochemical and biophysical research communications 229 (3), 752-757, 1996
841996
Increased fatty acid oxidation in transgenic mice overexpressing UCP3 in skeletal muscle
S Wang, A Subramaniam, MA Cawthorne, JC Clapham
Diabetes, Obesity and Metabolism 5 (5), 295-301, 2003
832003
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