Giuliana Fusco
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Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, ...
Science 358 (6369), 1440-1443, 2017
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, ...
Nature communications 5 (1), 1-8, 2014
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
J Lautenschlńger, AD Stephens, G Fusco, F Str÷hl, N Curry, ...
Nature communications 9 (1), 1-13, 2018
Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ...
Nature communications 7 (1), 1-12, 2016
Structural ensembles of membrane-bound α-synuclein reveal the molecular determinants of synaptic vesicle affinity
G Fusco, A De Simone, P Arosio, M Vendruscolo, G Veglia, CM Dobson
Scientific reports 6 (1), 1-9, 2016
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ...
Nature communications 11 (1), 1-15, 2020
Inhibition of α-synuclein fibril elongation by Hsp70 is governed by a kinetic binding competition between α-synuclein species
FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, ...
Biochemistry 56 (9), 1177-1180, 2017
Conformational recognition of an intrinsically disordered protein
JM Krieger, G Fusco, M Lewitzky, PC Simister, J Marchant, C Camilloni, ...
Biophysical journal 106 (8), 1771-1779, 2014
Order and disorder in the physiological membrane binding of α-synuclein
G Fusco, M Sanz-Hernandez, A De Simone
Current opinion in structural biology 48, 49-57, 2018
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
WK Man, B Tahirbegi, MD Vrettas, S Preet, L Ying, M Vendruscolo, ...
Nature communications 12 (1), 1-10, 2021
The N-terminal acetylation of α-synuclein changes the affinity for lipid membranes but not the structural properties of the bound state
M Runfola, A De Simone, M Vendruscolo, CM Dobson, G Fusco
Scientific Reports 10 (1), 1-10, 2020
Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies
R Cascella, M Perni, SW Chen, G Fusco, C Cecchi, M Vendruscolo, ...
ACS Chemical Biology 14 (6), 1352-1362, 2019
The toxicity of misfolded protein oligomers is independent of their secondary structure
M Vivoli Vega, R Cascella, SW Chen, G Fusco, A De Simone, CM Dobson, ...
ACS Chemical Biology 14 (7), 1593-1600, 2019
Molecular determinants of the interaction of EGCG with ordered and disordered proteins
G Fusco, M Sanz‐Hernandez, FS Ruggeri, M Vendruscolo, CM Dobson, ...
Biopolymers 109 (10), e23117, 2018
Structural basis for natural product selection and export by bacterial ABC transporters
M Romano, G Fusco, HG Choudhury, S Mehmood, CV Robinson, S Zirah, ...
ACS Chemical Biology 13 (6), 1598-1609, 2018
Membrane interactions and toxicity by misfolded protein oligomers
M Gonzalez-Garcia, G Fusco, A De Simone
Frontiers in Cell and Developmental Biology 9, 642623, 2021
A role of cholesterol in modulating the binding of α-synuclein to synaptic-like vesicles
WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco
Frontiers in neuroscience 14, 18, 2020
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
G Fusco, A De Simone, STD Hsu, F Bemporad, M Vendruscolo, F Chiti, ...
Biomolecular NMR assignments 6 (1), 27-29, 2012
Modeling Parkinson’s disease neuropathology and symptoms by intranigral inoculation of preformed human α-synuclein oligomers
L Boi, A Pisanu, MF Palmas, G Fusco, E Carboni, MA Casu, V Satta, ...
International journal of molecular sciences 21 (22), 8535, 2020
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
M Perni, A Van der Goot, R Limbocker, TJ Van Ham, FA Aprile, CK Xu, ...
Frontiers in cell and developmental biology 9, 552549, 2021
Il sistema al momento non pu˛ eseguire l'operazione. Riprova pi¨ tardi.
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