bathgate r*
bathgate r*
Florey Institute of Neuroscience and Mental Health
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INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent
J Kumagai, SY Hsu, H Matsumi, JS Roh, P Fu, JD Wade, RAD Bathgate, ...
Journal of Biological Chemistry 277 (35), 31283-31286, 2002
Relaxin family peptides and their receptors
RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ...
Physiological reviews 93 (1), 405-480, 2013
Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene: novel members of the relaxin peptide family
RAD Bathgate, CS Samuel, TCD Burazin, S Layfield, AA Claasz, ...
Journal of Biological Chemistry 277 (2), 1148-1157, 2002
Paracrine regulation of mammalian oocyte maturation and male germ cell survival
K Kawamura, J Kumagai, S Sudo, SY Chun, M Pisarska, H Morita, ...
Proceedings of the National Academy of Sciences 101 (19), 7323-7328, 2004
International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides
RA Bathgate, R Ivell, BM Sanborn, OD Sherwood, RJ Summers
Pharmacological reviews 58 (1), 7-31, 2006
Relaxin Modulates Cardiac Fibroblast Proliferation, Differentiation, and Collagen Production and Reverses Cardiac Fibrosis in Vivo
CS Samuel, EN Unemori, I Mookerjee, RAD Bathgate, SL Layfield, J Mak, ...
Endocrinology 145 (9), 4125-4133, 2004
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
S Sudo, J Kumagai, S Nishi, S Layfield, T Ferraro, RAD Bathgate, ...
Journal of Biological Chemistry 278 (10), 7855-7862, 2003
Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats
ED Lekgabe, H Kiriazis, C Zhao, Q Xu, XL Moore, Y Su, RAD Bathgate, ...
Hypertension 46 (2), 412-418, 2005
Evolution of the relaxin-like peptide family
TN Wilkinson, TP Speed, GW Tregear, RAD Bathgate
BMC evolutionary biology 5 (1), 1-17, 2005
Restricted, but abundant, expression of the novel rat gene‐3 (R3) relaxin in the dorsal tegmental region of brain
TCD Burazin, RAD Bathgate, M Macris, S Layfield, AL Gundlach, ...
Journal of neurochemistry 82 (6), 1553-1557, 2002
Relaxin deficiency in mice is associated with an age‐related progression of pulmonary fibrosis
CS Samuel, C Zhao, RAD Bathgate, CP Bond, MD Burton, LJ Parry, ...
The FASEB Journal 17 (1), 121-123, 2003
INSL5 is a high affinity specific agonist for GPCR142 (GPR100)
C Liu, C Kuei, S Sutton, J Chen, P Bonaventure, J Wu, D Nepomuceno, ...
Journal of Biological Chemistry 280 (1), 292-300, 2005
Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat
S Ma, P Bonaventure, T Ferraro, PJ Shen, TCD Burazin, RAD Bathgate, ...
Neuroscience 144 (1), 165-190, 2007
Cardiovascular effects of relaxin: from basic science to clinical therapy
XJ Du, RAD Bathgate, CS Samuel, AM Dart, RJ Summers
Nature Reviews Cardiology 7 (1), 48-58, 2010
The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth
Y Kubota, C Temelcos, RAD Bathgate, KJ Smith, D Scott, C Zhao, ...
Molecular human reproduction 8 (10), 900-905, 2002
Reproductive biology of the relaxin-like factor (RLF/INSL3)
R Ivell, RAD Bathgate
Biology of reproduction 67 (3), 699-705, 2002
Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo
RAD Bathgate, F Lin, NF Hanson, L Otvos, A Guidolin, C Giannakis, ...
Biochemistry 45 (3), 1043-1053, 2006
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules
DJ Scott, S Layfield, Y Yan, S Sudo, AJW Hsueh, GW Tregear, ...
Journal of Biological Chemistry 281 (46), 34942-34954, 2006
Distribution of relaxin‐3 and RXFP3 within arousal, stress, affective, and cognitive circuits of mouse brain
CM Smith, PJ Shen, A Banerjee, P Bonaventure, S Ma, RAD Bathgate, ...
Journal of Comparative Neurology 518 (19), 4016-4045, 2010
Relaxin: new peptides, receptors and novel actions
RAD Bathgate, CS Samuel, TCD Burazin, AL Gundlach, GW Tregear
Trends in Endocrinology & Metabolism 14 (5), 207-213, 2003
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