| ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice C Tiveron, L Fasulo, S Capsoni, F Malerba, S Marinelli, F Paoletti, ... Cell Death & Differentiation 20 (8), 1017-1030, 2013 | 86 | 2013 |
| Intranasal “painless” human nerve growth factors slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice S Capsoni, S Marinelli, M Ceci, D Vignone, G Amato, F Malerba, F Paoletti, ... PloS one 7 (5), e37555, 2012 | 82 | 2012 |
| Intranasal delivery of therapeutic proteins for neurological diseases F Malerba, F Paoletti, S Capsoni, A Cattaneo Expert opinion on drug delivery 8 (10), 1277-1296, 2011 | 78 | 2011 |
| Intrinsic structural disorder of mouse proNGF F Paoletti, S Covaceuszach, PV Konarev, S Gonfloni, F Malerba, ... Proteins: Structure, Function, and Bioinformatics 75 (4), 990-1009, 2009 | 75 | 2009 |
| Nerve growth factor regulates axial rotation during early stages of chick embryo development A Manca, S Capsoni, A Di Luzio, D Vignone, F Malerba, F Paoletti, ... Proceedings of the National Academy of Sciences 109 (6), 2009-2014, 2012 | 64 | 2012 |
| Functional characterization of human ProNGF and NGF mutants: identification of NGF P61SR100E as a “painless” lead investigational candidate for therapeutic applications F Malerba, F Paoletti, B Bruni Ercole, S Materazzi, R Nassini, E Coppi, ... PLoS One 10 (9), e0136425, 2015 | 46 | 2015 |
| The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor S Capsoni, F Malerba, NM Carucci, C Rizzi, C Criscuolo, N Origlia, ... Brain 140 (1), 201-217, 2017 | 42 | 2017 |
| Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer’s disease models V Corsetti, A Borreca, V Latina, G Giacovazzo, A Pignataro, P Krashia, ... Brain communications 2 (1), fcaa039, 2020 | 37* | 2020 |
| A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor F Paoletti, F Malerba, BB Ercole, D Lamba, A Cattaneo Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (3), 187-197, 2015 | 34 | 2015 |
| The mechanism of addition of pyridoxal 5′-phosphate to Escherichia coli apo-serine hydroxymethyltransferase F Malerba, A Bellelli, A Giorgi, F Bossa, R Contestabile Biochemical Journal 404 (3), 477-485, 2007 | 30 | 2007 |
| NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward F Malerba, F Paoletti, A Cattaneo Frontiers in molecular neuroscience 9, 63, 2016 | 28 | 2016 |
| NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling M D'Onofrio, F Paoletti, I Arisi, R Brandi, F Malerba, L Fasulo, A Cattaneo PLoS One 6 (6), e20839, 2011 | 27 | 2011 |
| Conformational plasticity of proNGF F Paoletti, F Malerba, G Kelly, S Noinville, D Lamba, A Cattaneo, ... PLoS One 6 (7), e22615, 2011 | 25 | 2011 |
| The NGFR100W mutation specifically impairs nociception without affecting cognitive performance in a mouse model of hereditary sensory and autonomic neuropathy type V G Testa, M Mainardi, C Morelli, F Olimpico, L Pancrazi, C Petrella, ... Journal of Neuroscience 39 (49), 9702-9715, 2019 | 21 | 2019 |
| Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease V Latina, G Giacovazzo, F Cordella, BO Balzamino, A Micera, M Varano, ... Acta Neuropathologica Communications 9, 1-27, 2021 | 20 | 2021 |
| Tau cleavage contributes to cognitive dysfunction in strepto-zotocin-induced sporadic Alzheimer’s disease (sAD) mouse model V Latina, G Giacovazzo, P Calissano, A Atlante, F La Regina, F Malerba, ... International Journal of Molecular Sciences 22 (22), 12158, 2021 | 17 | 2021 |
| proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces I Arisi, M D’Onofrio, R Brandi, F Malerba, F Paoletti, AE Storti, ... BMC neuroscience 15, 1-16, 2014 | 15 | 2014 |
| Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment F Paoletti, F Malerba, PV Konarev, M Visintin, R Scardigli, L Fasulo, ... Archives of biochemistry and biophysics 522 (1), 26-36, 2012 | 13 | 2012 |
| Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization C Severini, PP Passeri, MT Ciotti, F Florenzano, C Petrella, F Malerba, ... Neuropharmacology 117, 134-148, 2017 | 11 | 2017 |
| Nerve growth factor neutralization promotes oligodendrogenesis by increasing miR-219a-5p levels R Brandi, M Fabiano, C Giorgi, I Arisi, F La Regina, F Malerba, S Turturro, ... Cells 10 (2), 405, 2021 | 10 | 2021 |
