Christopher Chen

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N VenketasubramanianRaffles Neuroscience Centre, Raffles HospitalVerified email at rafflesmedical.com
Saima HilalAssistant ProfessorVerified email at nus.edu.sg
M.K. (Kamran) IkramProfessor of Clinical neuro-epidemiologyVerified email at erasmusmc.nl
Tien Yin Wong 黄天荫Tsinghua Medicine & Singapore National Eye CenterVerified email at nus.edu.sg
Mitchell K.P. LaiMemory, Aging and Cognition Ctr, National University of Singapore; University of Exeter, UKVerified email at dementia-research.org
Paul T FrancisUniversity of Exeter (previously King's College London)Verified email at exeter.ac.uk
Deidre Anne De SilvaNational Neuroscience InstituteVerified email at singhealth.com.sg
Carol Y Cheung, PhDDepartment of Ophthalmology and Visual Sciences, Faculty of Medicine, The Chinese University of HongVerified email at cuhk.edu.hk
Xin XuSenior research fellow, National University of SingaporeVerified email at nus.edu.sg
Henri VroomanBiomedical Imaging Group Rotterdam, Erasmus MC, University Medical Center, The NetherlandsVerified email at erasmusmc.nl
Ching-Yu Cheng, MD, MPH, PhDNational University of Singapore; and Singapore Eye Research InstituteVerified email at duke-nus.edu.sg
Bibek Gyanwali, MBBS, MD, PhDYong Loo Lin School of Medicine, National University of SingaporeVerified email at u.nus.edu
Geert Jan BiesselsVerified email at umcutrecht.nl
Vijay K SharmaAssociate Professor, YLL School of Medicine, National University of Singapore and Senior ConsultantVerified email at singnet.com.sg
SL CollinsonNational University of SingaporeVerified email at nus.edu.sg
Juan Helen ZhouAssociate Professor, National University of Singapore, SingaporeVerified email at nus.edu.sg
Graeme J. HankeyWInthrop Professor of Neurology, The University of Western Australia; Neurologist, Sir CharlesVerified email at uwa.edu.au
Raj KalariaProfessor of Pathology, Newcastle UniversityVerified email at ncl.ac.uk
Thiruma V. Arumugam (Garrie)Professor, La Trobe University; Sungkyunkwan UniversityVerified email at latrobe.edu.au
chuen seng tanAssistant Professor, National University of SingaporeVerified email at nus.edu.sg

Christopher Chen

Associate Professor, Department of Pharmacology, National University of Singapore

Verified email at nus.edu.sg

dementia stroke neuroimaging biomarkers clinical trials


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Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration JM Wardlaw, EE Smith, GJ Biessels, C Cordonnier, F Fazekas, R Frayne, ... The Lancet Neurology 12 (8), 822-838, 2013	4935*	2013
Lecanemab in early Alzheimer’s disease CH Van Dyck, CJ Swanson, P Aisen, RJ Bateman, C Chen, M Gee, ... New England Journal of Medicine 388 (1), 9-21, 2023	1619	2023
Diagnostic criteria for vascular cognitive disorders: a VASCOG statement P Sachdev, R Kalaria, J O’Brien, I Skoog, S Alladi, SE Black, D Blacker, ... Alzheimer Disease & Associated Disorders 28 (3), 206-218, 2014	754	2014
The amyloid-β pathway in Alzheimer’s disease H Hampel, J Hardy, K Blennow, C Chen, G Perry, SH Kim, VL Villemagne, ... Molecular psychiatry 26 (10), 5481-5503, 2021	674	2021
The Montreal Cognitive Assessment (MoCA) is superior to the Mini-Mental State Examination (MMSE) for the detection of vascular cognitive impairment after acute stroke YH Dong, VK Sharma, BPL Chan, N Venketasubramanian, HL Teoh, ... Journal of the neurological sciences 299 (1-2), 15-18, 2010	620	2010
Vascular dysfunction—the disregarded partner of Alzheimer's disease MD Sweeney, A Montagne, AP Sagare, DA Nation, LS Schneider, ... Alzheimer's & Dementia 15 (1), 158-167, 2019	567	2019
Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open … KSL Wong, C Chen, J Fu, HM Chang, NC Suwanwela, YN Huang, Z Han, ... The Lancet Neurology 9 (5), 489-497, 2010	545	2010
Nebivolol vasodilates human forearm vasculature: evidence for an L-arginine/NO-dependent mechanism. JR Cockcroft, PJ Chowienczyk, SE Brett, CP Chen, AG Dupont, ... Journal of Pharmacology and Experimental Therapeutics 274 (3), 1067-1071, 1995	521	1995
Vascular cognitive impairment WM Van Der Flier, I Skoog, JA Schneider, L Pantoni, V Mok, CLH Chen, ... Nature Reviews Disease Primers 4 (1), 1-16, 2018	479	2018
Hydrogen sulfide is a mediator of cerebral ischemic damage K Qu, CPLH Chen, B Halliwell, PK Moore, PTH Wong Stroke 37 (3), 889-893, 2006	372	2006
World‐Wide FINGERS Network: a global approach to risk reduction and prevention of dementia M Kivipelto, F Mangialasche, HM Snyder, R Allegri, S Andrieu, H Arai, ... Alzheimer's & dementia 16 (7), 1078-1094, 2020	330	2020
Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study OA Skrobot, SE Black, C Chen, C DeCarli, T Erkinjuntti, GA Ford, ... Alzheimer's & Dementia 14 (3), 280-292, 2018	316	2018
Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised … ENOS Trial Investigators The Lancet 385 (9968), 617-628, 2015	315	2015
Microvascular network alterations in the retina of patients with Alzheimer's disease CY Cheung, YT Ong, MK Ikram, SY Ong, X Li, S Hilal, JAS Catindig, ... Alzheimer's & Dementia 10 (2), 135-142, 2014	307	2014
Progression of cognitive impairment after stroke: one year results from a longitudinal study of Singaporean stroke patients W Tham, AP Auchus, M Thong, ML Goh, HM Chang, MC Wong, ... Journal of the neurological sciences 203, 49-52, 2002	295	2002
Spectral-domain OCT measurements in Alzheimer’s disease: a systematic review and meta-analysis VTT Chan, Z Sun, S Tang, LJ Chen, A Wong, CC Tham, TY Wong, ... Ophthalmology 126 (4), 497-510, 2019	285	2019
Detection, risk factors, and functional consequences of cerebral microinfarcts SJ van Veluw, AY Shih, EE Smith, C Chen, JA Schneider, JM Wardlaw, ... The Lancet Neurology 16 (9), 730-740, 2017	280	2017
Evidence that NF-κB and MAPK signaling promotes NLRP inflammasome activation in neurons following ischemic stroke DYW Fann, YA Lim, YL Cheng, KZ Lok, P Chunduri, SH Baik, ... Molecular neurobiology 55, 1082-1096, 2018	278	2018
Standardized assessment of automatic segmentation of white matter hyperintensities and results of the WMH segmentation challenge HJ Kuijf, JM Biesbroek, J De Bresser, R Heinen, S Andermatt, M Bento, ... IEEE transactions on medical imaging 38 (11), 2556-2568, 2019	268	2019
Retinal ganglion cell analysis using high-definition optical coherence tomography in patients with mild cognitive impairment and Alzheimer's disease CY Cheung, YT Ong, S Hilal, MK Ikram, S Low, YL Ong, ... Journal of Alzheimer's Disease 45 (1), 45-56, 2015	262	2015

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