| Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin CL Drum, SZ Yan, J Bard, YQ Shen, D Lu, S Soelaiman, Z Grabarek, ... Nature 415 (6870), 396-402, 2002 | 551 | 2002 |
| Adaptive licensing: taking the next step in the evolution of drug approval HG Eichler, K Oye, LG Baird, E Abadie, J Brown, CL Drum, J Ferguson, ... Clinical Pharmacology & Therapeutics 91 (3), 426-437, 2012 | 343 | 2012 |
| In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid–polymeric nanoparticles JM Chan, JW Rhee, CL Drum, RT Bronson, G Golomb, R Langer, ... Proceedings of the National Academy of Sciences 108 (48), 19347-19352, 2011 | 152 | 2011 |
| A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B GR Benzinger, JW Kyle, KM Blumenthal, DA Hanck Journal of Biological Chemistry 273 (1), 80-84, 1998 | 119 | 1998 |
| Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis B Halliwell, IK Cheah, CL Drum Biochemical and biophysical research communications 470 (2), 245-250, 2016 | 115 | 2016 |
| An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis CL Drum, SZ Yan, R Sarac, Y Mabuchi, K Beckingham, A Bohm, ... Journal of Biological Chemistry 275 (46), 36334-36340, 2000 | 85 | 2000 |
| Voltage-gated sodium channel toxins: poisons, probes, and future promise KM Blumenthal, AL Seibert Cell biochemistry and biophysics 38, 215-237, 2003 | 82 | 2003 |
| Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination PK Khera, GR Benzinger, G Lipkind, CL Drum, DA Hanck, KM Blumenthal Biochemistry 34 (27), 8533-8541, 1995 | 65 | 1995 |
| Photo-response behavior of electrospun nanofibers based on spiropyran-cyclodextrin modified polymer FB De Sousa, JDT Guerreiro, M Ma, DG Anderson, CL Drum, ... Journal of materials chemistry 20 (44), 9910-9917, 2010 | 61 | 2010 |
| Component‐specific analysis of plasma protein corona formation on gold nanoparticles using multiplexed surface plasmon resonance A Patra, T Ding, G Engudar, Y Wang, MM Dykas, B Liedberg, JCY Kah, ... Small 12 (9), 1174-1182, 2016 | 60 | 2016 |
| Prioritizing candidates of post–myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics MY Chan, M Efthymios, SH Tan, JW Pickering, R Troughton, C Pemberton, ... Circulation 142 (15), 1408-1421, 2020 | 55 | 2020 |
| Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease M Garcia-Miralles, J Ooi, CF Bardile, LJ Tan, M George, CL Drum, RY Lin, ... Experimental neurology 278, 4-10, 2016 | 49 | 2016 |
| Oral administration of protein nanoparticles: An emerging route to disease treatment S Sadeghi, WK Lee, SN Kong, A Shetty, CL Drum Pharmacological research 158, 104685, 2020 | 48 | 2020 |
| Differences in the binding sites of two site-3 sodium channel toxins GR Benzinger, CL Drum, LQ Chen, RG Kallen, DA Hanck, D Hanck Pflügers Archiv 434, 742-749, 1997 | 48 | 1997 |
| Superstructure based on β-CD self-assembly induced by a small guest molecule FB De Sousa, AC Lima, ÂML Denadai, CPA Anconi, WB De Almeida, ... Physical Chemistry Chemical Physics 14 (6), 1934-1944, 2012 | 45 | 2012 |
| Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ... Science Translational Medicine 13 (597), eaba8146, 2021 | 44 | 2021 |
| Leucine 18, a Hydrophobic Residue Essential for High Affinity Binding of Anthopleurin B to the Voltage-sensitive Sodium Channel (∗) BL Dias-Kadambi, CL Drum, DA Hanck, KM Blumenthal Journal of Biological Chemistry 271 (16), 9422-9428, 1996 | 39 | 1996 |
| The importance of sex stratification in autoimmune disease biomarker research: a systematic review K Purnamawati, JAH Ong, S Deshpande, WKY Tan, N Masurkar, JK Low, ... Frontiers in immunology 9, 1208, 2018 | 32 | 2018 |
| Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in the presence of its activator, calmodulin CL Drum, Y Shen, PA Rice, A Bohm, WJ Tang Acta Crystallographica Section D: Biological Crystallography 57 (12), 1881-1884, 2001 | 32 | 2001 |
| Surface protein engineering increases the circulation time of a cell membrane-based nanotherapeutic S Krishnamurthy, P Muthukumaran, MKG Jayakumar, D Lisse, ... Nanomedicine: Nanotechnology, Biology and Medicine 18, 169-178, 2019 | 31 | 2019 |
