The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling K Izutsu, M Kurokawa, Y Imai, K Maki, K Mitani, H Hirai Blood, The Journal of the American Society of Hematology 97 (9), 2815-2822, 2001 | 291 | 2001 |
Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis Y Imai, M Kurokawa, K Izutsu, A Hangaishi, K Takeuchi, K Maki, S Ogawa, ... Blood, The Journal of the American Society of Hematology 96 (9), 3154-3160, 2000 | 202 | 2000 |
The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability T Tanaka, M Kurokawa, K Ueki, K Tanaka, Y Imai, K Mitani, K Okazaki, ... Molecular and cellular biology, 1996 | 199 | 1996 |
Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity K Kataoka, T Sato, A Yoshimi, S Goyama, T Tsuruta, H Kobayashi, ... Journal of Experimental Medicine 208 (12), 2403-2416, 2011 | 195 | 2011 |
Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins A Yoshimi, S Goyama, N Watanabe-Okochi, Y Yoshiki, Y Nannya, E Nitta, ... Blood, The Journal of the American Society of Hematology 117 (13), 3617-3628, 2011 | 169 | 2011 |
Influence of pretransplantation serum ferritin on nonrelapse mortality after myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantation K Kataoka, Y Nannya, A Hangaishi, Y Imai, S Chiba, T Takahashi, ... Biology of Blood and Marrow Transplantation 15 (2), 195-204, 2009 | 154 | 2009 |
TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation Y Imai, M Kurokawa, K Tanaka, AD Friedman, S Ogawa, K Mitani, ... Biochemical and biophysical research communications 252 (3), 582-589, 1998 | 151 | 1998 |
Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders K Ueda, Y Nannya, K Kumano, A Hangaishi, T Takahashi, Y Imai, ... International journal of hematology 89, 592-599, 2009 | 140 | 2009 |
The t (3; 21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-β–mediated growth inhibition of myeloid cells M Kurokawa, K Mitani, Y Imai, S Ogawa, Y Yazaki, H Hirai Blood, The Journal of the American Society of Hematology 92 (11), 4003-4012, 1998 | 139 | 1998 |
AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues Y Yamaguchi, M Kurokawa, Y Imai, K Izutsu, T Asai, M Ichikawa, ... Journal of Biological Chemistry 279 (15), 15630-15638, 2004 | 127 | 2004 |
The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1 Y Imai, M Kurokawa, Y Yamaguchi, K Izutsu, E Nitta, K Mitani, M Satake, ... Molecular and cellular biology, 2004 | 126 | 2004 |
Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes EJ Park, A Peixoto, Y Imai, A Goodarzi, G Cheng, CV Carman, ... Blood, The Journal of the American Society of Hematology 115 (8), 1572-1581, 2010 | 124 | 2010 |
Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells S Arai, A Yoshimi, M Shimabe, M Ichikawa, M Nakagawa, Y Imai, ... Blood, The Journal of the American Society of Hematology 117 (23), 6304-6314, 2011 | 115 | 2011 |
Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis Y Imai, M Kurokawa, K Izutsu, A Hangaishi, K Maki, S Ogawa, S Chiba, ... Oncogene 20 (1), 88-96, 2001 | 110 | 2001 |
Notch1 oncoprotein antagonizes TGF‐β/Smad‐mediated cell growth suppression via sequestration of coactivator p300 S Masuda, K Kumano, K Shimizu, Y Imai, M Kurokawa, S Ogawa, ... Cancer science 96 (5), 274-282, 2005 | 96 | 2005 |
The effect of iron overload and chelation on erythroid differentiation K Taoka, K Kumano, F Nakamura, M Hosoi, S Goyama, Y Imai, ... International journal of hematology 95, 149-159, 2012 | 84 | 2012 |
EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization S Goyama, E Nitta, T Yoshino, S Kako, N Watanabe-Okochi, M Shimabe, ... Leukemia 24 (1), 81-88, 2010 | 83 | 2010 |
Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells M Shimabe, S Goyama, N Watanabe-Okochi, A Yoshimi, M Ichikawa, ... Oncogene 28 (49), 4364-4374, 2009 | 82 | 2009 |
Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies Y Imai, Y Maru, J Tanaka Cancer science 107 (11), 1543-1549, 2016 | 70 | 2016 |
Essential roles of VLA-4 in the hematopoietic system Y Imai, M Shimaoka, M Kurokawa International journal of hematology 91, 569-575, 2010 | 68 | 2010 |