Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and double JS-K, through incorporation into PEG-protected nanoparticles V Kumar, SY Hong, AE Maciag, JE Saavedra, DH Adamson, ... Molecular pharmaceutics 7 (1), 291-298, 2010 | 98 | 2010 |
Rapamycin-inspired macrocycles with new target specificity Z Guo, SY Hong, J Wang, S Rehan, W Liu, H Peng, M Das, W Li, S Bhat, ... Nature chemistry 11 (3), 254-263, 2019 | 82 | 2019 |
Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of mTOR signaling and angiogenesis SA Head, WQ Shi, EJ Yang, BA Nacev, SY Hong, KK Pasunooti, RJ Li, ... ACS chemical biology 12 (1), 174-182, 2017 | 74 | 2017 |
“Click” reaction in conjunction with diazeniumdiolate chemistry: developing high-load nitric oxide donors OA Oladeinde, SY Hong, RJ Holland, AE Maciag, LK Keefer, JE Saavedra, ... Organic letters 12 (19), 4256-4259, 2010 | 32 | 2010 |
Discovery of a potent GLUT inhibitor from a library of rapafucins by using 3D microarrays Z Guo, Z Cheng, J Wang, W Liu, H Peng, Y Wang, AVS Rao, R Li, X Ying, ... Angewandte Chemie 131 (48), 17318-17322, 2019 | 29 | 2019 |
Activation of the c-Jun N-terminal kinase/activating transcription factor 3 (ATF3) pathway characterizes effective arylated diazeniumdiolate-based nitric oxide-releasing … AE Maciag, RS Nandurdikar, SY Hong, H Chakrapani, B Diwan, ... Journal of medicinal chemistry 54 (22), 7751-7758, 2011 | 25 | 2011 |
Anti-tumor effects of Codonopsis lanceolata extracts on human lung and ovarian cancer YR Cho, SH Kim, HJ Yoon, SY Hong, HY Ko, EH Park, MD Kim, DW Seo Food Engineering Progress 15 (1), 1-5, 2011 | 12 | 2011 |
The nitric oxide prodrug V-PROLI/NO inhibits cellular uptake of proline SY Hong, GL Borchert, AE Maciag, RS Nandurdikar, JE Saavedra, ... ACS medicinal chemistry letters 1 (8), 386-389, 2010 | 10 | 2010 |
Glycosylated PROLI/NO derivatives as nitric oxide prodrugs RS Nandurdikar, AE Maciag, SY Hong, H Chakrapani, ML Citro, ... Organic letters 12 (1), 56-59, 2010 | 10 | 2010 |
Improved synthesis of V-PYRRO/NO, a liver-selective nitric oxide prodrug, and analogues SY Hong, JE Saavedra, LK Keefer, H Chakrapani Tetrahedron Letters 50 (18), 2069-2071, 2009 | 8 | 2009 |
Ginsenoside Rp1 inhibits proliferation and migration of human lung cancer cells SY Hong, JY Cho, DW Seo Biomolecules & Therapeutics 19 (4), 411-418, 2011 | 7 | 2011 |
Nitric oxide donor, V-PROLI/NO, provides protection against arsenical induced toxicity in rat liver cells: Requirement for Cyp1a1 W Qu, L Cheng, AL Dill, JE Saavedra, SY Hong, LK Keefer, MP Waalkes Chemico-biological interactions 193 (1), 88-96, 2011 | 6 | 2011 |
Influence of stereochemistry on the activity of rapadocin, an isoform-specific inhibitor of the nucleoside transporter ENT1 Y Wang, H Peng, Z Guo, BR Ullman, K Yamamoto, SY Hong, JO Liu Chemical Science 12 (34), 11484-11489, 2021 | 4 | 2021 |
An improved synthesis of V-PROLI/NO, a cytochrome P450-activated nitric oxide prodrug SY Hong, RS Nandurdikar, LK Keefer, JE Saavedra, H Chakrapani Tetrahedron Letters 50 (31), 4545-4548, 2009 | 4 | 2009 |
Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof J Liu, J Wang, Z Sun, S Hong US Patent 10,774,110, 2020 | 3 | 2020 |
Synthesis and composition of rapafucin libraries J Liu, J Wang, Z Guo, S Hong, W Liu, H Peng, M Das US Patent 10,662,220, 2020 | 2 | 2020 |
Rapafucin derivative compounds and methods of use thereof J Liu, S Hong, BR Ullman, JE Semple, K Yamamoto, P Kumar, ... US Patent 11,945,827, 2024 | | 2024 |
Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof J Liu, J Wang, Z Sun, S Hong US Patent 11,555,054, 2023 | | 2023 |
Rapafucin derivative compounds and methods of use thereof S Hong, BR Ullman, JE Semple, K Yamamoto, P Kumar, M Sadagopan, ... US Patent App. 17/765,814, 2023 | | 2023 |
Neuroprotective compounds and methods of use thereof TM Dawson, VL Dawson, J Liu, H Park, TI Kam, H Peng, VS Ayinampudi, ... US Patent App. 17/765,418, 2022 | | 2022 |