| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1390 | 2013 |
| Aryl hydrocarbon receptor-mediated signal transduction JC Rowlands, JÅ Gustafsson Critical reviews in toxicology 27 (2), 109-134, 1997 | 653 | 1997 |
| Machine learning of toxicological big data enables read-across structure activity relationships (RASAR) outperforming animal test reproducibility T Luechtefeld, D Marsh, C Rowlands, T Hartung Toxicological Sciences 165 (1), 198-212, 2018 | 270 | 2018 |
| Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework RS Thomas, MA Philbert, SS Auerbach, BA Wetmore, MJ Devito, I Cote, ... toxicological sciences 136 (1), 4-18, 2013 | 257 | 2013 |
| The health consequences of early soy consumption TM Badger, MJJ Ronis, R Hakkak, JC Rowlands, S Korourian The Journal of nutrition 132 (3), 559S-565S, 2002 | 195 | 2002 |
| Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors. JC Rowlands, IJ Mcewan, JA Gustafsson Molecular pharmacology 50 (3), 538-548, 1996 | 155 | 1996 |
| Risk assessment in the 21st century: roadmap and matrix MR Embry, AN Bachman, DR Bell, AR Boobis, SM Cohen, M Dellarco, ... Critical reviews in toxicology 44 (sup3), 6-16, 2014 | 122 | 2014 |
| A 21st century roadmap for human health risk assessment TP Pastoor, AN Bachman, DR Bell, SM Cohen, M Dellarco, IC Dewhurst, ... Critical reviews in toxicology 44 (sup3), 1-5, 2014 | 120 | 2014 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibition of 17β-estradiol-induced increases in rat uterine epidermal growth factor receptor binding activity and gene expression B Astroff, C Rowlands, R Dickerson, S Safe Molecular and cellular endocrinology 72 (3), 247-252, 1990 | 115 | 1990 |
| Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes G Patlewicz, TW Simon, JC Rowlands, RA Budinsky, RA Becker Regulatory Toxicology and Pharmacology 71 (3), 463-477, 2015 | 113 | 2015 |
| The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy S Zhang, P Lei, X Liu, X Li, K Walker, L Kotha, C Rowlands, S Safe Endocrine-related cancer 16 (3), 835-844, 2009 | 113 | 2009 |
| Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats JC Rowlands, L He, R Hakkak, MJJ Ronis, TM Badger The Journal of nutrition 131 (12), 3281-3287, 2001 | 110 | 2001 |
| Endocrine disruption: historical perspectives and its impact on the future of toxicology testing MS Marty, EW Carney, JC Rowlands Toxicological Sciences 120 (suppl_1), S93-S108, 2011 | 95 | 2011 |
| Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice JA Harrill, RR Hukkanen, M Lawson, G Martin, B Gilger, V Soldatow, ... Toxicology and applied pharmacology 272 (2), 503-518, 2013 | 89 | 2013 |
| Estrogenic and antiproliferative properties of soy sapogenols in human breast cancer cells in vitro JC Rowlands, MA Berhow, TM Badger Food and Chemical Toxicology 40 (12), 1767-1774, 2002 | 86 | 2002 |
| Estrogenic and antiproliferative properties of soy sapogenols in human breast cancer cells in vitro JC Rowlands, MA Berhow, TM Badger Food and Chemical Toxicology 40 (12), 1767-1774, 2002 | 86 | 2002 |
| Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study RA Budinsky, D Schrenk, T Simon, M Van den Berg, JF Reichard, ... Critical reviews in toxicology 44 (1), 83-119, 2014 | 84 | 2014 |
| CATMoS: collaborative acute toxicity modeling suite K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ... Environmental health perspectives 129 (4), 047013, 2021 | 83 | 2021 |
| Cross-species Comparisons of Transcriptomic Alterations in Human and Rat Primary Hepatocytes Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin MB Black, RA Budinsky, A Dombkowski, D Cukovic, EL LeCluyse, ... Toxicological Sciences 127 (1), 199-215, 2012 | 74 | 2012 |
| Big-data and machine learning to revamp computational toxicology and its use in risk assessment T Luechtefeld, C Rowlands, T Hartung Toxicology research 7 (5), 732-744, 2018 | 73 | 2018 |
Russell S ThomasDirector, Center for Computational Toxicology and Exposure, U.S. Environmental Protection AgencyEmail verificata su epa.gov
