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Amberley D Stephens
Amberley D Stephens
Email verificata su astrazeneca.com
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C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
J Lautenschlńger, AD Stephens, G Fusco, F Str÷hl, N Curry, ...
Nature communications 9 (1), 1-13, 2018
2072018
Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ...
Nature communications 7 (1), 1-12, 2016
1962016
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ...
Nature communications 11 (1), 1-15, 2020
592020
The cellular environment affects monomeric α-synuclein structure
AD Stephens, M Zacharopoulou, GSK Schierle
Trends in biochemical sciences 44 (5), 453-466, 2019
532019
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, ...
Elife 8, e43059, 2019
402019
Different structural conformers of monomeric alpha-synuclein identified after lyophilising and freezing
AD Stephens, N Nespovitaya, M Zacharopoulou, CF Kaminski, JJ Phillips, ...
Analytical chemistry, 2018
312018
The role of water in amyloid aggregation kinetics
AD Stephens, GSK Schierle
Current Opinion in Structural Biology 58, 115-123, 2019
212019
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
J Lautenschlńger, S Wagner-Valladolid, AD Stephens, ...
Journal of Biological Chemistry 295 (30), 10138-10152, 2020
202020
Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements
RM Delahay, NJ Croxall, AD Stephens
Mobile DNA 9 (1), 1-20, 2018
182018
Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy
TA Shmool, PJ Woodhams, M Leutzsch, AD Stephens, MU Gaimann, ...
International journal of pharmaceutics: X 1, 100022, 2019
172019
Short hydrogen bonds enhance nonaromatic protein-related fluorescence
AD Stephens, MN Qaisrani, MT Ruggiero, G DÝaz Mirˇn, UN Morzan, ...
Proceedings of the National Academy of Sciences 118 (21), e2020389118, 2021
132021
Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, STE Jones, D Credgington, ...
Physical Chemistry Chemical Physics 21 (43), 23931-23942, 2019
122019
Purification of recombinant α-Synuclein: a comparison of commonly used protocols
A Stephens, D Matak-Vinkovic, A Fernandez-Villegas, ...
Biochemistry 59 (48), 4563-4572, 2020
92020
TE; Credgington, D.; Kaminski Schierle, GS; Hassanali, A. Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, S Jones
Phys. Chem. Chem. Phys 21 (43), 23931-23942, 2019
62019
Fast Purification of Recombinant Monomeric Amyloid‑β from E. coli and Amyloid-β-mCherry Aggregates from Mammalian Cells
A Stephens, M Lu, A Fernandez-Villegas, G Kaminski Schierle
ACS Chemical Neuroscience 11, 3204-3213, 2020
52020
C-terminal calcium binding of alpha-synuclein modulates synaptic vesicle interaction. Nat. Commun. 9 (1), 712
J Lautenschlager, AD Stephens, G Fusco, F Strohl, N Curry, ...
52018
Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property
CW Chung, AD Stephens, E Ward, Y Feng, MJ Davis, CF Kaminski, ...
Analytical Chemistry 94 (13), 5367–5374, 2022
42022
Extent of N-terminus exposure by altered long-range interactions of monomeric alpha-synuclein determines its aggregation propensity
AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ...
bioRxiv, 740241, 2019
42019
Intracellular Aβ42 aggregation leads to cellular thermogenesis
CW Chung, AD Stephens, T Konno, E Ward, E Avezov, CF Kaminski, ...
Journal of the American Chemical Society, 2022
32022
Intrinsic fluorescence in non-aromatic peptide structures is induced by collective vibrations, charge reorganisation and short hydrogen bonds, as shown in a new glutamineá…
AD Stephens, MN Qaisrani, MT Ruggiero, STE Jones, E Poli, AD Bond, ...
bioRxiv, 2020.01. 22.915306, 2020
22020
Il sistema al momento non pu˛ eseguire l'operazione. Riprova pi¨ tardi.
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