Courtney Aldrich
Courtney Aldrich
University of Minnesota, Department of Medicinal Chemistry
Verified email at umn.edu - Homepage
Title
Cited by
Cited by
Year
Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of mycobacterium t uberculosis
RV Somu, H Boshoff, C Qiao, EM Bennett, CE Barry, CC Aldrich
Journal of medicinal chemistry 49 (1), 31-34, 2006
2782006
The ecstasy and agony of assay interference compounds
C Aldrich, C Bertozzi, GI Georg, L Kiessling, C Lindsley, D Liotta, ...
ACS Chemical Neuroscience 8 (3), 420-423, 2017
1682017
Structures of two distinct conformations of holo-non-ribosomal peptide synthetases
EJ Drake, BR Miller, C Shi, JT Tarrasch, JA Sundlov, CL Allen, G Skiniotis, ...
Nature 529 (7585), 235-238, 2016
1422016
Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure− activity relationships of the nucleobase domain of 5′-O …
J Neres, NP Labello, RV Somu, HI Boshoff, DJ Wilson, J Vannada, ...
Journal of medicinal chemistry 51 (17), 5349-5370, 2008
1352008
Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains
JA Sundlov, C Shi, DJ Wilson, CC Aldrich, AM Gulick
Chemistry & biology 19 (2), 188-198, 2012
1152012
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression
SW Park, M Klotzsche, DJ Wilson, HI Boshoff, H Eoh, U Manjunatha, ...
PLoS Pathog 7 (9), e1002264, 2011
1122011
Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains
CA Mitchell, C Shi, CC Aldrich, AM Gulick
Biochemistry 51 (15), 3252-3263, 2012
1102012
Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis
JY Lee, BK Janes, KD Passalacqua, BF Pfleger, NH Bergman, H Liu, ...
Journal of bacteriology 189 (5), 1698-1710, 2007
1062007
Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5′-O-[N-(salicyl) sulfamoyl] adenosine: antibacterial nucleosides effective against Mycobacterium …
A Gupte, HI Boshoff, DJ Wilson, J Neres, NP Labello, RV Somu, C Xing, ...
Journal of medicinal chemistry 51 (23), 7495-7507, 2008
1052008
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence
JH Kim, KM O’Brien, R Sharma, HIM Boshoff, G Rehren, S Chakraborty, ...
Proceedings of the National Academy of Sciences 110 (47), 19095-19100, 2013
1002013
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243
T Nishizawa, CC Aldrich, DH Sherman
Journal of Bacteriology 187 (6), 2084-2092, 2005
992005
5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA:  An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins
C Qiao, A Gupte, HI Boshoff, DJ Wilson, EM Bennett, RV Somu, CE Barry, ...
Journal of medicinal chemistry 50 (24), 6080-6094, 2007
962007
Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain
RV Somu, DJ Wilson, EM Bennett, HI Boshoff, L Celia, BJ Beck, CE Barry, ...
Journal of medicinal chemistry 49 (26), 7623-7635, 2006
902006
Mitsunobu reactions catalytic in phosphine and a fully catalytic system
JA Buonomo, CC Aldrich
Angewandte Chemie 127 (44), 13233-13236, 2015
852015
Copper (II)-catalyzed conversion of aryl/heteroaryl boronic acids, boronates, and trifluoroborates into the corresponding azides: substrate scope and limitations
KD Grimes, A Gupte, CC Aldrich
Synthesis 2010 (9), 1441, 2010
782010
Design, synthesis, and biological evaluation of β-ketosulfonamide adenylation inhibitors as potential antitubercular agents
J Vannada, EM Bennett, DJ Wilson, HI Boshoff, CE Barry, CC Aldrich
Organic letters 8 (21), 4707-4710, 2006
732006
Total synthesis of the calphostins: application of fischer carbene complexes and thermodynamic control of atropisomers
CA Merlic, CC Aldrich, J Albaneze-Walker, A Saghatelian, J Mammen
The Journal of organic chemistry 66 (4), 1297-1309, 2001
732001
Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis
BP Duckworth, TW Geders, D Tiwari, HI Boshoff, PA Sibbald, CE Barry Iii, ...
Chemistry & biology 18 (11), 1432-1441, 2011
722011
A mechanism-based aryl carrier protein/thiolation domain affinity probe
C Qiao, DJ Wilson, EM Bennett, CC Aldrich
Journal of the American Chemical Society 129 (20), 6350-6351, 2007
702007
Triazole-Linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human and Mycobacterium tuberculosis
L Chen, DJ Wilson, Y Xu, CC Aldrich, K Felczak, YY Sham, ...
Journal of medicinal chemistry 53 (12), 4768-4778, 2010
672010
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