| Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of mycobacterium t uberculosis RV Somu, H Boshoff, C Qiao, EM Bennett, CE Barry, CC Aldrich Journal of medicinal chemistry 49 (1), 31-34, 2006 | 278 | 2006 |
| The ecstasy and agony of assay interference compounds C Aldrich, C Bertozzi, GI Georg, L Kiessling, C Lindsley, D Liotta, ... ACS Chemical Neuroscience 8 (3), 420-423, 2017 | 168 | 2017 |
| Structures of two distinct conformations of holo-non-ribosomal peptide synthetases EJ Drake, BR Miller, C Shi, JT Tarrasch, JA Sundlov, CL Allen, G Skiniotis, ... Nature 529 (7585), 235-238, 2016 | 142 | 2016 |
| Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure− activity relationships of the nucleobase domain of 5′-O … J Neres, NP Labello, RV Somu, HI Boshoff, DJ Wilson, J Vannada, ... Journal of medicinal chemistry 51 (17), 5349-5370, 2008 | 135 | 2008 |
| Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains JA Sundlov, C Shi, DJ Wilson, CC Aldrich, AM Gulick Chemistry & biology 19 (2), 188-198, 2012 | 115 | 2012 |
| Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression SW Park, M Klotzsche, DJ Wilson, HI Boshoff, H Eoh, U Manjunatha, ... PLoS Pathog 7 (9), e1002264, 2011 | 112 | 2011 |
| Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains CA Mitchell, C Shi, CC Aldrich, AM Gulick Biochemistry 51 (15), 3252-3263, 2012 | 110 | 2012 |
| Biosynthetic analysis of the petrobactin siderophore pathway from Bacillus anthracis JY Lee, BK Janes, KD Passalacqua, BF Pfleger, NH Bergman, H Liu, ... Journal of bacteriology 189 (5), 1698-1710, 2007 | 106 | 2007 |
| Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5′-O-[N-(salicyl) sulfamoyl] adenosine: antibacterial nucleosides effective against Mycobacterium … A Gupte, HI Boshoff, DJ Wilson, J Neres, NP Labello, RV Somu, C Xing, ... Journal of medicinal chemistry 51 (23), 7495-7507, 2008 | 105 | 2008 |
| A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence JH Kim, KM O’Brien, R Sharma, HIM Boshoff, G Rehren, S Chakraborty, ... Proceedings of the National Academy of Sciences 110 (47), 19095-19100, 2013 | 100 | 2013 |
| Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243 T Nishizawa, CC Aldrich, DH Sherman Journal of Bacteriology 187 (6), 2084-2092, 2005 | 99 | 2005 |
| 5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA: An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins C Qiao, A Gupte, HI Boshoff, DJ Wilson, EM Bennett, RV Somu, CE Barry, ... Journal of medicinal chemistry 50 (24), 6080-6094, 2007 | 96 | 2007 |
| Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain RV Somu, DJ Wilson, EM Bennett, HI Boshoff, L Celia, BJ Beck, CE Barry, ... Journal of medicinal chemistry 49 (26), 7623-7635, 2006 | 90 | 2006 |
| Mitsunobu reactions catalytic in phosphine and a fully catalytic system JA Buonomo, CC Aldrich Angewandte Chemie 127 (44), 13233-13236, 2015 | 85 | 2015 |
| Copper (II)-catalyzed conversion of aryl/heteroaryl boronic acids, boronates, and trifluoroborates into the corresponding azides: substrate scope and limitations KD Grimes, A Gupte, CC Aldrich Synthesis 2010 (9), 1441, 2010 | 78 | 2010 |
| Design, synthesis, and biological evaluation of β-ketosulfonamide adenylation inhibitors as potential antitubercular agents J Vannada, EM Bennett, DJ Wilson, HI Boshoff, CE Barry, CC Aldrich Organic letters 8 (21), 4707-4710, 2006 | 73 | 2006 |
| Total synthesis of the calphostins: application of fischer carbene complexes and thermodynamic control of atropisomers CA Merlic, CC Aldrich, J Albaneze-Walker, A Saghatelian, J Mammen The Journal of organic chemistry 66 (4), 1297-1309, 2001 | 73 | 2001 |
| Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis BP Duckworth, TW Geders, D Tiwari, HI Boshoff, PA Sibbald, CE Barry Iii, ... Chemistry & biology 18 (11), 1432-1441, 2011 | 72 | 2011 |
| A mechanism-based aryl carrier protein/thiolation domain affinity probe C Qiao, DJ Wilson, EM Bennett, CC Aldrich Journal of the American Chemical Society 129 (20), 6350-6351, 2007 | 70 | 2007 |
| Triazole-Linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human and Mycobacterium tuberculosis L Chen, DJ Wilson, Y Xu, CC Aldrich, K Felczak, YY Sham, ... Journal of medicinal chemistry 53 (12), 4768-4778, 2010 | 67 | 2010 |
Clifton E Barry IIINIAIDVerified email at niaid.nih.gov
