| Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of mycobacterium t uberculosis RV Somu, H Boshoff, C Qiao, EM Bennett, CE Barry, CC Aldrich Journal of medicinal chemistry 49 (1), 31-34, 2006 | 306 | 2006 |
| The ecstasy and agony of assay interference compounds C Aldrich, C Bertozzi, GI Georg, L Kiessling, C Lindsley, D Liotta, ... ACS Chemical Neuroscience 8 (3), 420-423, 2017 | 301 | 2017 |
| Structures of two distinct conformations of holo-non-ribosomal peptide synthetases EJ Drake, BR Miller, C Shi, JT Tarrasch, JA Sundlov, C Leigh Allen, ... Nature 529 (7585), 235-238, 2016 | 247 | 2016 |
| Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains CA Mitchell, C Shi, CC Aldrich, AM Gulick Biochemistry 51 (15), 3252-3263, 2012 | 161 | 2012 |
| Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains JA Sundlov, C Shi, DJ Wilson, CC Aldrich, AM Gulick Chemistry & biology 19 (2), 188-198, 2012 | 158 | 2012 |
| Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: Structure− activity relationships of the nucleobase domain of 5′-O … J Neres, NP Labello, RV Somu, HI Boshoff, DJ Wilson, J Vannada, ... Journal of medicinal chemistry 51 (17), 5349-5370, 2008 | 155 | 2008 |
| Evaluating the Sensitivity of Mycobacterium tuberculosis to Biotin Deprivation Using Regulated Gene Expression S Woong Park, M Klotzsche, DJ Wilson, HI Boshoff, H Eoh, U Manjunatha, ... PLoS pathogens 7 (9), e1002264, 2011 | 148 | 2011 |
| A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence JH Kim, KM O’Brien, R Sharma, HIM Boshoff, G Rehren, S Chakraborty, ... Proceedings of the National Academy of Sciences 110 (47), 19095-19100, 2013 | 143 | 2013 |
| Mitsunobu reactions catalytic in phosphine and a fully catalytic system JA Buonomo, CC Aldrich Angewandte Chemie 127 (44), 13233-13236, 2015 | 141 | 2015 |
| Biosynthetic Analysis of the Petrobactin Siderophore Pathway from Bacillusanthracis JY Lee, BK Janes, KD Passalacqua, BF Pfleger, NH Bergman, H Liu, ... Journal of bacteriology 189 (5), 1698-1710, 2007 | 132 | 2007 |
| Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5′-O-[N-(salicyl) sulfamoyl] adenosine: antibacterial nucleosides effective against Mycobacterium … A Gupte, HI Boshoff, DJ Wilson, J Neres, NP Labello, RV Somu, C Xing, ... Journal of medicinal chemistry 51 (23), 7495-7507, 2008 | 118 | 2008 |
| Molecular Analysis of the Rebeccamycin l-Amino Acid Oxidase from Lechevalieria aerocolonigenes ATCC 39243 T Nishizawa, CC Aldrich, DH Sherman Journal of Bacteriology 187 (6), 2084-2092, 2005 | 117 | 2005 |
| 5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA: An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins C Qiao, A Gupte, HI Boshoff, DJ Wilson, EM Bennett, RV Somu, CE Barry, ... Journal of medicinal chemistry 50 (24), 6080-6094, 2007 | 112 | 2007 |
| Structures of a nonribosomal peptide synthetase module bound to MbtH-like proteins support a highly dynamic domain architecture BR Miller, EJ Drake, C Shi, CC Aldrich, AM Gulick Journal of Biological Chemistry 291 (43), 22559-22571, 2016 | 108 | 2016 |
| Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain RV Somu, DJ Wilson, EM Bennett, HI Boshoff, L Celia, BJ Beck, CE Barry, ... Journal of medicinal chemistry 49 (26), 7623-7635, 2006 | 108 | 2006 |
| Copper (II)-catalyzed conversion of aryl/heteroaryl boronic acids, boronates, and trifluoroborates into the corresponding azides: substrate scope and limitations KD Grimes, A Gupte, CC Aldrich Synthesis 2010 (09), 1441-1448, 2010 | 103 | 2010 |
| A continuous kinetic assay for adenylation enzyme activity and inhibition DJ Wilson, CC Aldrich Analytical biochemistry 404 (1), 56-63, 2010 | 100 | 2010 |
| A mechanism-based aryl carrier protein/thiolation domain affinity probe C Qiao, DJ Wilson, EM Bennett, CC Aldrich Journal of the American Chemical Society 129 (20), 6350-6351, 2007 | 97 | 2007 |
| Mutual potentiation drives synergy between trimethoprim and sulfamethoxazole Y Minato, S Dawadi, SL Kordus, A Sivanandam, CC Aldrich, AD Baughn Nature communications 9 (1), 1003, 2018 | 96 | 2018 |
| Engineering the substrate specificity of the DhbE adenylation domain by yeast cell surface display K Zhang, KM Nelson, K Bhuripanyo, KD Grimes, B Zhao, CC Aldrich, J Yin Chemistry & Biology 20 (1), 92-101, 2013 | 93 | 2013 |
Clifton E Barry IIINIAIDEmail verificata su niaid.nih.gov
