Francesco Grignani
Francesco Grignani
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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction
G Pelicci, L Lanfrancone, F Grignani, J McGlade, F Cavallo, G Forni, ...
Cell 70 (1), 93-104, 1992
Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia
F Grignani, S De Matteis, C Nervi, L Tomassoni, V Gelmetti, M Cioce, ...
Nature 391 (6669), 815-818, 1998
The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
F Grignani, PF Ferrucci, U Testa, G Talamo, M Fagioli, M Alcalay, ...
Cell 74 (3), 423-431, 1993
Acute promyelocytic leukemia: from genetics to treatment
F Grignani, M Fagioli, M Alcalay, L Longo, PP Pandolfi, E Donti, A Biondi, ...
MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
L Fontana, E Pelosi, P Greco, S Racanicchi, U Testa, F Liuzzi, CM Croce, ...
Nature cell biology 9 (7), 775-787, 2007
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
R De Maria, A Zeuner, A Eramo, C Domenichelli, D Bonci, F Grignani, ...
Nature 401 (6752), 489-493, 1999
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein
F Fazi, S Racanicchi, G Zardo, LM Starnes, M Mancini, L Travaglini, ...
Cancer cell 12 (5), 457-466, 2007
High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein
F Grignani, T Kinsella, A Mencarelli, M Valtieri, D Riganelli, F Grignani, ...
Cancer research 58 (1), 14-19, 1998
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties.
PP Pandolfi, F Grignani, M Alcalay, A Mencarelli, A Biondi, F LoCoco, ...
Oncogene 6 (7), 1285-1292, 1991
N-(4-Hydroxyphenyl)retinamide Induces Apoptosis of Malignant Hemopoietic Cell Lines Including Those Unresponsive to Retinoic Acid
D Delia, A Aiello, L Lombardi, PG Pelicci, F Grignani, F Grignani, ...
Cancer Research 53 (24), 6036-6041, 1993
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane: retention of caveolin-2 at the level of the golgi complex
I Parolini, M Sargiacomo, F Galbiati, G Rizzo, F Grignani, JA Engelman, ...
Journal of Biological Chemistry 274 (36), 25718-25725, 1999
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
C Labbaye, I Spinello, MT Quaranta, E Pelosi, L Pasquini, E Petrucci, ...
Nature Cell Biology 10 (7), 788-801, 2008
Caspases mediate retinoic acid–induced degradation of the acute promyelocytic leukemia PML/RARα fusion protein
C Nervi, FF Ferrara, M Fanelli, MR Rippo, B Tomassini, PF Ferrucci, ...
Blood, The Journal of the American Society of Hematology 92 (7), 2244-2251, 1998
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein
M Alcalay, L Tomassoni, E Colombo, S Stoldt, F Grignani, M Fagioli, ...
Molecular and cellular biology 18 (2), 1084-1093, 1998
Down-regulation of LFA-1 adhesion receptors by C-myc oncogene in human B lymphoblastoid cells
G Inghirami, F Grignani, L Sternas, L Lombardi, DM Knowles, ...
Science 250 (4981), 682-686, 1990
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression
G Zardo, A Ciolfi, L Vian, LM Starnes, M Billi, S Racanicchi, C Maresca, ...
Blood, The Journal of the American Society of Hematology 119 (17), 4034-4046, 2012
Growth-and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.
G Nunez, M Seto, S Seremetis, D Ferrero, F Grignani, SJ Korsmeyer, ...
Proceedings of the National Academy of Sciences 86 (12), 4589-4593, 1989
Human CD4 lymphocytes specifically recognize a peptide representing the fusion region of the hybrid protein pml/RAR alpha present in acute promyelocytic leukemia cells
C Gambacorti-Passerini, F Grignani, F Arienti, PP Pandolfi, PG Pelicci, ...
Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.
F Grignani, U Testa, D Rogaia, PF Ferrucci, P Samoggia, A Pinto, ...
The EMBO Journal 15 (18), 4949-4958, 1996
Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor α (RARα) and PLZF-RARα fusion proteins on retinoic acid signalling
M Ruthardt, U Testa, C Nervi, PF Ferrucci, F Grignani, E Puccetti, ...
Molecular and cellular biology 17 (8), 4859-4869, 1997
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