| The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. CT Chien, PL Bartel, R Sternglanz, S Fields Proceedings of the National Academy of Sciences 88 (21), 9578-9582, 1991 | 2373 | 1991 |
| Elimination of false positives that arise in using the two-hybrid system. P Bartel, CT Chien, R Sternglanz, S Fields Biotechniques 14 (6), 920-924, 1993 | 786 | 1993 |
| Using the two-hybrid system to detect protein-protein interactions P Bartel, CT Chien, R Sternglanz, S Fields Cellular interactions in development, 153-180, 1993 | 623 | 1993 |
| A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor Q Zhang, L Zhang, B Wang, CY Ou, CT Chien, J Jiang Developmental cell 10 (6), 719-729, 2006 | 265 | 2006 |
| Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast C Chien, S Buck, R Sternglanz, D Shore Cell 75 (3), 531-541, 1993 | 251 | 1993 |
| Functional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replication BCM Tan, CT Chien, S Hirose, SC Lee The EMBO journal 25 (17), 3975-3985, 2006 | 219 | 2006 |
| Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development CY Ou, YF Lin, YJ Chen, CT Chien Genes & development 16 (18), 2403-2414, 2002 | 218 | 2002 |
| Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation JT Wu, HC Lin, YC Hu, CT Chien Nature cell biology 7 (10), 1014-1020, 2005 | 217 | 2005 |
| LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3β CH Lin, PI Tsai, RM Wu, CT Chien Journal of Neuroscience 30 (39), 13138-13149, 2010 | 202 | 2010 |
| F-box proteins: the key to protein degradation MS Ho, PI Tsai, CT Chien Journal of biomedical science 13, 181-191, 2006 | 185 | 2006 |
| The utility F-box for protein destruction MS Ho, C Ou, Y Chan, CT Chien, H Pi Cellular and Molecular Life Sciences 65, 1977-2000, 2008 | 159 | 2008 |
| Neuronal type information encoded in the basic-helix–loop–helix domain of proneural genes C Chien, CD Hsiao, LY Jan, YN Jan Proceedings of the National Academy of Sciences 93 (23), 13239-13244, 1996 | 154 | 1996 |
| The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system ML Huang, CH Hsu, CT Chien Neuron 25 (1), 57-67, 2000 | 117 | 2000 |
| Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c YC Chen, HY Kuo, U Bornschein, H Takahashi, SY Chen, KM Lu, ... Nature neuroscience 19 (11), 1513-1522, 2016 | 104 | 2016 |
| Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo C Chien, S Wang, M Rothenberg, LY Jan, YN Jan Molecular and cellular biology 18 (1), 598-607, 1998 | 104 | 1998 |
| Transcriptional Activation upon Pheromone Stimulation Mediated by a Small Domain of Saccharomyces cerevisiae Ste12p H Pi, CT Chien, S Fields Molecular and cellular biology 17 (11), 6410-6418, 1997 | 93 | 1997 |
| DEN1 deneddylates non-cullin proteins in vivo Y Chan, J Yoon, JT Wu, HJ Kim, KT Pan, J Yim, CT Chien Journal of cell science 121 (19), 3218-3223, 2008 | 84 | 2008 |
| Protection of cullin–RING E3 ligases by CSN–UBP12 JT Wu, YR Chan, CT Chien Trends in cell biology 16 (7), 362-369, 2006 | 81 | 2006 |
| Cell cycle roles for two 14-3-3 proteins during Drosophila development TT Su, DH Parry, B Donahoe, CT Chien, PH O’Farrell, A Purdy Journal of cell science 114 (19), 3445-3454, 2001 | 72 | 2001 |
| Scabrous controls ommatidial rotation in the Drosophila compound eye YH Chou, CT Chien Developmental Cell 3 (6), 839-850, 2002 | 59 | 2002 |
Tsai Pei-IUCSF, Dept. of Biochemistry and BiophysicsEmail verificata su UCSF.edu
