Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH da Costa, ... Nature 537 (7621), 544-547, 2016 | 522 | 2016 |
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis S Cardaci, L Zheng, G MacKay, NJF Van Den Broek, ED MacKenzie, ... Nature cell biology, 2015 | 276 | 2015 |
Fumarate induces redox-dependent senescence by modifying glutathione metabolism L Zheng, S Cardaci, L Jerby, ED MacKenzie, M Sciacovelli, TI Johnson, ... Nature communications 6, 2015 | 263 | 2015 |
Redox implications of AMPK-mediated signal transduction beyond energetic clues S Cardaci, G Filomeni, MR Ciriolo J Cell Sci 125 (9), 2115-2125, 2012 | 234 | 2012 |
Under the ROS: Thiol network is the principal suspect for autophagy commitment G Filomeni, E Desideri, S Cardaci, G Rotilio, MR Ciriolo Autophagy 6 (7), 999-1005, 2010 | 181 | 2010 |
TCA cycle defects and cancer: when metabolism tunes redox state S Cardaci, MR Ciriolo International journal of cell biology 2012, 2012 | 179 | 2012 |
Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug S Cardaci, E Desideri, MR Ciriolo Journal of bioenergetics and biomembranes 44 (1), 17-29, 2012 | 141 | 2012 |
Reactive oxygen species mediate p53 activation and apoptosis induced by sodium nitroprusside in SH-SY5Y cells S Cardaci, G Filomeni, G Rotilio, MR Ciriolo Molecular pharmacology 74 (5), 1234-1245, 2008 | 108 | 2008 |
Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells LC Godoy, C Muñoz-Pinedo, L Castro, S Cardaci, CM Schonhoff, M King, ... Proceedings of the National Academy of Sciences 106 (8), 2653-2658, 2009 | 104 | 2009 |
Carcinoma cells activate AMP-activated protein kinase-dependent autophagy as survival response to kaempferol-mediated energetic impairment G Filomeni, E Desideri, S Cardaci, I Graziani, S Piccirillo, G Rotilio, ... Autophagy 6 (2), 202-216, 2010 | 80 | 2010 |
MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation E Desideri, R Vegliante, S Cardaci, R Nepravishta, M Paci, MR Ciriolo Autophagy 10 (9), 1652-1665, 2014 | 75 | 2014 |
Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells K Aquilano, S Baldelli, S Cardaci, G Rotilio, MR Ciriolo J Cell Sci 124 (7), 1043-1054, 2011 | 72 | 2011 |
S-nitrosylation of the mitochondrial chaperone TRAP1 sensitizes hepatocellular carcinoma cells to inhibitors of succinate dehydrogenase. S Rizza, C Montagna, S Cardaci, E Maiani, G Di Giacomo, ... Cancer research, canres. 2637.2015, 2016 | 69 | 2016 |
The isatin-Schiff base copper (II) complex Cu (isaepy) 2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated … G Filomeni, S Piccirillo, I Graziani, S Cardaci, AMDC Ferreira, G Rotilio, ... Carcinogenesis 30 (7), 1115-1124, 2009 | 67 | 2009 |
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 S Cardaci, S Rizza, G Filomeni, R Bernardini, F Bertocchi, M Mattei, ... Cancer research 72 (17), 4526-4536, 2012 | 54 | 2012 |
S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction C Montagna, G Di Giacomo, S Rizza, S Cardaci, E Ferraro, P Grumati, ... Antioxidants & redox signaling 21 (4), 570-587, 2014 | 49 | 2014 |
Metabolic oxidative stress elicited by the copper (II) complex [Cu (isaepy) 2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase … G Filomeni, S Cardaci, AMDC Ferreira, G Rotilio, MR Ciriolo Biochemical Journal 437 (3), 443-453, 2011 | 45 | 2011 |
p38MAPK/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration S Cardaci, G Filomeni, G Rotilio, MR Ciriolo Biochemical Journal 430 (3), 439-451, 2010 | 43 | 2010 |
S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson’s Disease and Amyotrophic Lateral Sclerosis S Rizza, C Cirotti, C Montagna, S Cardaci, C Consales, M Cozzolino, ... Mediators of inflammation 2015, 2015 | 17 | 2015 |
Deprive to kill: glutamine closes the gate to anticancer monocarboxylic drugs S Cardaci, MR Ciriolo Autophagy 8 (12), 1830-1832, 2012 | 6 | 2012 |