SH2 domains recognize specific phosphopeptide sequences S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ... Cell 72 (5), 767-778, 1993 | 3225 | 1993 |
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway LC Cantley, BG Neel Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999 | 2527 | 1999 |
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis WS Hayward, BG Neel, SM Astrin Nature 290 (5806), 475-480, 1981 | 1787 | 1981 |
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice LD Klaman, O Boss, OD Peroni, JK Kim, JL Martino, JM Zabolotny, ... Molecular and cellular biology 20 (15), 5479-5489, 2000 | 1411 | 2000 |
The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling BG Neel, H Gu, L Pao Trends in biochemical sciences 28 (6), 284-293, 2003 | 1242 | 2003 |
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins JV Frangioni, BG Neel Analytical biochemistry 210 (1), 179-187, 1993 | 1118 | 1993 |
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals U Klingmüller, U Lorenz, LC Cantley, BG Neel, HF Lodish Cell 80 (5), 729-738, 1995 | 1081 | 1995 |
STAT3 signalling is required for leptin regulation of energy balance but not reproduction SH Bates, WH Stearns, TA Dundon, M Schubert, AWK Tso, Y Wang, ... Nature 421 (6925), 856-859, 2003 | 1063 | 2003 |
Protein tyrosine phosphatases in signal transduction BG Neel, NK Tonks Current opinion in cell biology 9 (2), 193-204, 1997 | 939 | 1997 |
PTP1B regulates leptin signal transduction in vivo JM Zabolotny, KK Bence-Hanulec, A Stricker-Krongrad, F Haj, Y Wang, ... Developmental cell 2 (4), 489-495, 2002 | 870 | 2002 |
The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence JV Frangioni, PH Beahm, V Shifrin, CA Jost, BG Neel Cell 68 (3), 545-560, 1992 | 680 | 1992 |
From form to function: signaling by protein tyrosine phosphatases NK Tonks, BG Neel Cell 87 (3), 365-368, 1996 | 650 | 1996 |
Combinatorial control of the specificity of protein tyrosine phosphatases NK Tonks, BG Neel Current opinion in cell biology 13 (2), 182-195, 2001 | 620 | 2001 |
Neuronal PTP1B regulates body weight, adiposity and leptin action KK Bence, M Delibegovic, B Xue, CZ Gorgun, GS Hotamisligil, BG Neel, ... Nature medicine 12 (8), 917-924, 2006 | 618 | 2006 |
Mathematical models of protein kinase signal transduction R Heinrich, BG Neel, TA Rapoport Molecular cell 9 (5), 957-970, 2002 | 612 | 2002 |
Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion BG Neel, WS Hayward, HL Robinson, J Fang, SM Astrin Cell 23 (2), 323-334, 1981 | 597 | 1981 |
Germline gain-of-function mutations in SOS1 cause Noonan syndrome AE Roberts, T Araki, KD Swanson, KT Montgomery, TA Schiripo, VA Joshi, ... Nature genetics 39 (1), 70-74, 2007 | 561 | 2007 |
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia M Bentires-Alj, JG Paez, FS David, H Keilhack, B Halmos, K Naoki, ... Cancer research 64 (24), 8816-8820, 2004 | 493 | 2004 |
Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum FG Haj, PJ Verveer, A Squire, BG Neel, PIH Bastiaens Science 295 (5560), 1708-1711, 2002 | 479 | 2002 |
Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment SQ Zhang, W Yang, MI Kontaridis, TG Bivona, G Wen, T Araki, J Luo, ... Molecular cell 13 (3), 341-355, 2004 | 474 | 2004 |