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Huwenbo Shi
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Integrative approaches for large-scale transcriptome-wide association studies
A Gusev, A Ko, H Shi, G Bhatia, W Chung, BWJH Penninx, R Jansen, ...
Nature genetics 48 (3), 245-252, 2016
17132016
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7002021
Contrasting the genetic architecture of 30 complex traits from summary association data
H Shi, G Kichaev, B Pasaniuc
American Journal of Human Genetics 99 (1), 139–153, 2016
3902016
Probabilistic fine-mapping of transcriptome-wide association studies
N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ...
Nature genetics 51 (4), 675-682, 2019
2792019
Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank
Z Zhu, Y Guo, H Shi, CL Liu, RA Panganiban, W Chung, LJ O'Connor, ...
Journal of Allergy and Clinical Immunology 145 (2), 537-549, 2020
2572020
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits
N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc
The American Journal of Human Genetics 100 (3), 473-487, 2017
2552017
Local genetic correlation gives insights into the shared genetic architecture of complex traits
H Shi, N Mancuso, S Spendlove, B Pasaniuc
The American Journal of Human Genetics 101 (5), 737-751, 2017
2402017
A Bayesian framework for multiple trait colocalization from summary association statistics
C Giambartolomei, J Zhenli Liu, W Zhang, M Hauberg, H Shi, J Boocock, ...
Bioinformatics 34 (15), 2538-2545, 2018
2212018
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
B Pasaniuc, N Zaitlen, H Shi, G Bhatia, A Gusev, J Pickrell, J Hirschhorn, ...
Bioinformatics 30 (20), 2906-2914, 2014
2082014
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores
O Weissbrod*, M Kanai*, H Shi*, S Gazal, WJ Peyrot, AV Khera, Y Okada, ...
Nature Genetics, 1-9, 2022
146*2022
Population-specific causal disease effect sizes in functionally important regions impacted by selection
H Shi, S Gazal, M Kanai, EM Koch, AP Schoech, KM Siewert, SS Kim, ...
Nature communications 12 (1), 1098, 2021
1272021
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis
Z Zhu, X Zhu, CL Liu, H Shi, S Shen, Y Yang, K Hasegawa, CA Camargo, ...
European Respiratory Journal 54 (6), 2019
1202019
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice
LD Orozco, M Morselli, L Rubbi, W Guo, J Go, H Shi, D Lopez, NA Furlotte, ...
Cell metabolism 21 (6), 905-917, 2015
1082015
Technology dictates algorithms: recent developments in read alignment
M Alser, J Rotman, D Deshpande, K Taraszka, H Shi, PI Baykal, HT Yang, ...
Genome biology 22 (1), 249, 2021
1052021
Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture
K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ...
Nature Genetics 51, 1244–1251, 2019
1012019
Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits
MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ...
The American Journal of Human Genetics 103 (4), 535-552, 2018
882018
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity
S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ...
Nature genetics 54 (6), 827-836, 2022
752022
Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data
H Shi*, KS Burch*, R Johnson, MK Freund, G Kichaev, N Mancuso, ...
The American Journal of Human Genetics 106 (6), 805-817, 2020
692020
The missing link between genetic association and regulatory function
NJ Connally, S Nazeen, D Lee, H Shi, J Stamatoyannopoulos, S Chun, ...
Elife 11, e74970, 2022
562022
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
A Gusev, H Shi, G Kichaev, M Pomerantz, F Li, HW Long, SA Ingles, ...
Nature communications 7 (1), 10979, 2016
532016
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Articles 1–20