| Small molecule inhibitors of CXCR4 B Debnath, S Xu, F Grande, A Garofalo, N Neamati Theranostics 3 (1), 47, 2013 | 301 | 2013 |
| Titanium dioxide nanoparticles: a risk for human health? F Grande, P Tucci Mini reviews in medicinal chemistry 16 (9), 762-769, 2016 | 249 | 2016 |
| Small molecule inhibitors of Stat3 signaling pathway J Deng, F Grande, N Neamati Current cancer drug targets 7 (1), 91-107, 2007 | 168 | 2007 |
| Synthesis and antitumor activities of a series of novel quinoxalinhydrazides F Grande, F Aiello, O De Grazia, A Brizzi, A Garofalo, N Neamati Bioorganic & medicinal chemistry 15 (1), 288-294, 2007 | 144 | 2007 |
| Discovery of a novel orally active small-molecule gp130 inhibitor for the treatment of ovarian cancer S Xu, F Grande, A Garofalo, N Neamati Molecular cancer therapeutics 12 (6), 937-949, 2013 | 132 | 2013 |
| Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update M Millard, D Pathania, F Grande, S Xu, N Neamati Current pharmaceutical design 17 (6), 536-559, 2011 | 80 | 2011 |
| Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization F Grande, OI Parisi, RA Mordocco, C Rocca, F Puoci, L Scrivano, ... European Journal of Pharmaceutical Sciences 82, 161-170, 2016 | 73 | 2016 |
| Small molecules anti-HIV therapeutics targeting CXCR4 F Grande, A Garofalo, N Neamati Current pharmaceutical design 14 (4), 385-404, 2008 | 69 | 2008 |
| Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs B Rizzuti, F Grande, F Conforti, A Jimenez-Alesanco, L Ceballos-Laita, ... Biomedicines 9 (4), 375, 2021 | 62 | 2021 |
| Identification by Molecular Docking of Homoisoflavones from Leopoldia comosa as Ligands of Estrogen Receptors F Grande, B Rizzuti, MA Occhiuzzi, G Ioele, T Casacchia, F Gelmini, ... Molecules 23 (4), 894, 2018 | 62 | 2018 |
| New insights for the use of quercetin analogs in cancer treatment D Iacopetta, F Grande, A Caruso, RA Mordocco, MR Plutino, L Scrivano, ... Future medicinal chemistry 9 (17), 2011-2028, 2017 | 59 | 2017 |
| Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression D Rovito, G Gionfriddo, I Barone, C Giordano, F Grande, F De Amicis, ... Oncotarget 7 (40), 65109, 2016 | 54 | 2016 |
| Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca, A Garofalo, G Ragno, ... Molecules 27 (17), 5436, 2022 | 51 | 2022 |
| An update on small molecules targeting CXCR4 as starting points for the development of anti-cancer therapeutics F Grande, G Giancotti, G Ioele, MA Occhiuzzi, A Garofalo European journal of medicinal chemistry 139, 519-530, 2017 | 50 | 2017 |
| Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats IC Nettore, C Rocca, G Mancino, L Albano, D Amelio, F Grande, F Puoci, ... The Journal of nutritional biochemistry 69, 151-162, 2019 | 45 | 2019 |
| Synthesis of novel thiazolothiazepine based HIV-1 integrase inhibitors F Aiello, A Brizzi, A Garofalo, F Grande, G Ragno, R Dayam, N Neamati Bioorganic & medicinal chemistry 12 (16), 4459-4466, 2004 | 40 | 2004 |
| Stabilization of MDA-7/IL-24 for colon cancer therapy S Xu, T Oshima, T Imada, M Masuda, B Debnath, F Grande, A Garofalo, ... Cancer letters 335 (2), 421-430, 2013 | 39 | 2013 |
| Dual inhibition of survivin and MAOA synergistically impairs growth of PTEN-negative prostate cancer S Xu, H Adisetiyo, S Tamura, F Grande, A Garofalo, P Roy-Burman, ... British journal of Cancer 113 (2), 242-251, 2015 | 38 | 2015 |
| Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts M Maggiolini, MF Santolla, S Avino, F Aiello, C Rosano, A Garofalo, ... Future Medicinal Chemistry 7 (4), 437-448, 2015 | 38 | 2015 |
| AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) F Cirillo, R Lappano, L Bruno, B Rizzuti, F Grande, R Guzzi, S Briguori, ... Journal of Experimental & Clinical Cancer Research 38, 1-18, 2019 | 37 | 2019 |
