| Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil SC S Omoto, V Speranzini, T Hashimoto, T Noshi, H Yamaguchi, M Kawai, K ... Scientific Reports 8, 9633, 2018 | 370 | 2018 |
| Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation S Pilotto, V Speranzini, M Tortorici, D Durand, A Fish, S Valente, ... Proceedings of the National Academy of Sciences 112 (9), 2752-2757, 2015 | 92 | 2015 |
| Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features V Speranzini, D Rotili, G Ciossani, S Pilotto, B Marrocco, M Forgione, ... Science advances 2 (9), e1601017, 2016 | 67 | 2016 |
| LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors S Pilotto, V Speranzini, C Marabelli, F Rusconi, E Toffolo, B Grillo, ... Human molecular genetics 25 (12), 2578-2587, 2016 | 51 | 2016 |
| Touch, act and go: landing and operating on nucleosomes V Speranzini, S Pilotto, TK Sixma, A Mattevi The EMBO journal 35 (4), 376-388, 2016 | 28 | 2016 |
| Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids PR Marchetti M, Liuzzi A, Fermi B, Corsini R, Folli C, Speranzini V ... Scientific Reports 6, 38302, 2016 | 26 | 2016 |
| Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep 8: 9633 S Omoto, V Speranzini, T Hashimoto, T Noshi, H Yamaguchi, M Kawai, ... | 22 | 2018 |
| An N-glycosylation hotspot in immunoglobulin κ light chains is associated with AL amyloidosis A Nevone, M Girelli, S Mangiacavalli, B Paiva, P Milani, P Cascino, ... Leukemia 36 (8), 2076-2085, 2022 | 16 | 2022 |
| Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018; 8 (1): 9633 S Omoto, V Speranzini, T Hashimoto, T Noshi, H Yamaguchi, M Kawai Epub 2018/06/27. https://doi. org/10.1038/s41598-018-27890-4 PMID: 29941893, 0 | 13 | |
| Probing the interaction of the p53 C-terminal domain to the histone demethylase LSD1 V Speranzini, G Ciossani, C Marabelli, A Mattevi Archives of biochemistry and biophysics 632, 202-208, 2017 | 8 | 2017 |
| Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter T Schulte, A Chaves-Sanjuan, G Mazzini, V Speranzini, F Lavatelli, F Ferri, ... Nature communications 13 (1), 7041, 2022 | 7 | 2022 |
| Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018; 8: 9633 S Omoto, V Speranzini, T Hashimoto, T Noshi, H Yamaguchi, M Kawai, ... | 7 | |
| Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106 T Kouba, A Dubankova, P Drncova, E Donati, P Vidossich, V Speranzini, ... Cell Reports 42 (1), 2023 | 4 | 2023 |
| Nanobodies as novel potential drugs to target cardiac light chain amyloidosis L Broggini, M Giono, V Speranzini, MM Barzago, G Palladini, L Diomede, ... Cardiovascular Research 118 (Supplement_1), cvac066. 233, 2022 | 2 | 2022 |
| Backtracking of influenza polymerase upon consecutive incorporation of nucleoside analogue T1106 directly observed by high-resolution cryo-electron microscopy T Kouba, A Dubankova, P Drncova, E Donati, P Vidossich, V Speranzini, ... bioRxiv, 2022.06. 10.495428, 2022 | 1 | 2022 |
| Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models S Jasmine, A Mandl, TEG Krueger, SL Dalrymple, L Antony, J Dias, ... The Prostate, 2024 | | 2024 |
| LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer A Mandl, S Jasmine, TEG Krueger, R Kumar, IM Coleman, SL Dalrymple, ... bioRxiv, 2024.01. 17.576106, 2024 | | 2024 |
| Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation L Broggini, MM Barzago, V Speranzini, T Schulte, F Sonzini, M Giono, ... Journal of Molecular Biology 435 (24), 168320, 2023 | | 2023 |
| Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis. S Ricagno, T Schulte, A Chaves-Sanjuan, V Speranzini, K Sicking, ... | | 2023 |
| Protein-Ligand binding measurements using fluorescence polarization V Speranzini, A Fish, A Mattevi | | |
