| New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) A Rossello, E Nuti, E Orlandini, P Carelli, S Rapposelli, M Macchia, ... Bioorganic & medicinal chemistry 12 (9), 2441-2450, 2004 | 101 | 2004 |
| N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential … E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ... Journal of medicinal chemistry 52 (15), 4757-4773, 2009 | 80 | 2009 |
| Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma P Gabelloni, E Da Pozzo, S Bendinelli, B Costa, E Nuti, F Casalini, ... Neuroscience 168 (2), 514-522, 2010 | 75 | 2010 |
| Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors E Nuti, L Panelli, F Casalini, SI Avramova, E Orlandini, S Santamaria, ... Journal of medicinal chemistry 52 (20), 6347-6361, 2009 | 69 | 2009 |
| N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity E Nuti, AR Cantelmo, C Gallo, A Bruno, B Bassani, C Camodeca, ... Journal of Medicinal Chemistry 58 (18), 7224-7240, 2015 | 65 | 2015 |
| Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups M Bozdag, M Ferraroni, F Carta, D Vullo, L Lucarini, E Orlandini, ... Journal of Medicinal Chemistry 57 (21), 9152-9167, 2014 | 59 | 2014 |
| Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates E Nuti, E Orlandini, S Nencetti, A Rossello, A Innocenti, A Scozzafava, ... Bioorganic & medicinal chemistry 15 (6), 2298-2311, 2007 | 59 | 2007 |
| Ni-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP A Rossello, E Nuti, P Carelli, E Orlandini, M Macchia, S Nencetti, ... Bioorganic & medicinal chemistry letters 15 (5), 1321-1326, 2005 | 54 | 2005 |
| Synthesis of heteroaromatic analogues of (2-aryl-1-cyclopentenyl-1-alkylidene)-(arylmethyloxy) amine COX-2 inhibitors: effects on the inhibitory activity of the replacement of … A Balsamo, I Coletta, A Guglielmotti, C Landolfi, F Mancini, A Martinelli, ... European journal of medicinal chemistry 38 (2), 157-168, 2003 | 52 | 2003 |
| Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease G Fancellu, K Chand, D Tomás, E Orlandini, L Piemontese, DF Silva, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 211-226, 2020 | 51 | 2020 |
| Synthesis and COX-2 inhibitory properties of N-phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl) cyclopent-1-ene-1-carboxylic acid and of their pyrazole … S Rapposelli, A Lapucci, F Minutolo, E Orlandini, G Ortore, M Pinza, ... Il Farmaco 59 (1), 25-31, 2004 | 47 | 2004 |
| Potent arylsulfonamide inhibitors of tumor necrosis factor-α converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models E Nuti, F Casalini, SI Avramova, S Santamaria, M Fabbi, S Ferrini, ... Journal of medicinal chemistry 53 (6), 2622-2635, 2010 | 46 | 2010 |
| Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis SK Palaninathan, NN Mohamedmohaideen, E Orlandini, G Ortore, ... PLoS One 4 (7), e6290, 2009 | 44 | 2009 |
| Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit α- and β-Carbonic Anhydrase: X-ray … AM Marini, A Maresca, M Aggarwal, E Orlandini, S Nencetti, F Da Settimo, ... Journal of Medicinal Chemistry 55 (22), 9619-9629, 2012 | 43 | 2012 |
| Sugar‐Based Arylsulfonamide Carboxylates as Selective and Water‐Soluble Matrix Metalloproteinase‐12 Inhibitors E Nuti, D Cuffaro, F D'Andrea, L Rosalia, L Tepshi, M Fabbi, G Carbotti, ... ChemMedChem 11 (15), 1626-1637, 2016 | 41 | 2016 |
| Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: Analysis of structural data for future drug design L Ciccone, N Tonali, S Nencetti, E Orlandini Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1145-1162, 2020 | 40 | 2020 |
| Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: synthesis and biological evaluation E Nuti, S Santamaria, F Casalini, K Yamamoto, L Marinelli, V La Pietra, ... European journal of medicinal chemistry 62, 379-394, 2013 | 40 | 2013 |
| Development of thioaryl-based matrix metalloproteinase-12 inhibitors with alternative zinc-binding groups: Synthesis, potentiometric, NMR, and crystallographic studies E Nuti, D Cuffaro, E Bernardini, C Camodeca, L Panelli, S Chaves, ... Journal of Medicinal Chemistry 61 (10), 4421-4435, 2018 | 39 | 2018 |
| Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues E Nuti, B Bassani, C Camodeca, L Rosalia, AR Cantelmo, C Gallo, D Baci, ... European journal of medicinal chemistry 138, 890-899, 2017 | 36 | 2017 |
| TTR fibril formation inhibitors: is there a SAR? S Nencetti, E Orlandini Current medicinal chemistry 19 (15), 2356-2379, 2012 | 36 | 2012 |
Armando RosselloFull Professor of Medicinal Chemistry, Università di Pisa, Dipartimento di FarmaciaEmail verificata su farm.unipi.it
