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Nicole Kleinstreuer
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Anno
Chronic inflammation in the etiology of disease across the life span
D Furman, J Campisi, E Verdin, P Carrera-Bastos, S Targ, C Franceschi, ...
Nature medicine 25 (12), 1822-1832, 2019
32602019
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
4992012
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
3412015
Zebrafish developmental screening of the ToxCast™ Phase I chemical library
S Padilla, D Corum, B Padnos, DL Hunter, A Beam, KA Houck, N Sipes, ...
Reproductive toxicology 33 (2), 174-187, 2012
3342012
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
2632016
Screening chemicals for estrogen receptor bioactivity using a computational model
P Browne, RS Judson, WM Casey, NC Kleinstreuer, RS Thomas
Environmental science & technology 49 (14), 8804-8814, 2015
2582015
In vitro to in vivo extrapolation for high throughput prioritization and decision making
SM Bell, X Chang, JF Wambaugh, DG Allen, M Bartels, KLR Brouwer, ...
Toxicology in vitro 47, 213-227, 2018
2162018
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data
NS Sipes, MT Martin, DM Reif, NC Kleinstreuer, RS Judson, AV Singh, ...
Toxicological Sciences 124 (1), 109-127, 2011
2082011
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
NC Kleinstreuer, J Yang, EL Berg, TB Knudsen, AM Richard, MT Martin, ...
Nature biotechnology 32 (6), 583-591, 2014
2022014
T4 report: Toward good read-across practice (GRAP) guidance
N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ...
Altex 33 (2), 149, 2016
1942016
Development and validation of a computational model for androgen receptor activity
NC Kleinstreuer, P Ceger, ED Watt, M Martin, K Houck, P Browne, ...
Chemical research in toxicology 30 (4), 946-964, 2017
1892017
Integrated Testing Strategies (ITS) for safety assessment.
C Rovida, N Alpe, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ...
ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015
1742015
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
NC Kleinstreuer, S Hoffmann, N Alpe, D Allen, T Ashikaga, W Casey, ...
Critical reviews in toxicology 48 (5), 359-374, 2018
1702018
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
S Hoffmann, N Kleinstreuer, N Alpe, D Allen, AM Api, T Ashikaga, ...
Critical reviews in toxicology 48 (5), 344-358, 2018
1552018
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
TB Knudsen, KA Houck, NS Sipes, AV Singh, RS Judson, MT Martin, ...
Toxicology 282 (1-2), 1-15, 2011
1552011
In silico prediction of physicochemical properties of environmental chemicals using molecular fingerprints and machine learning
Q Zang, K Mansouri, AJ Williams, RS Judson, DG Allen, WM Casey, ...
Journal of chemical information and modeling 57 (1), 36-49, 2017
1472017
CoMPARA: collaborative modeling project for androgen receptor activity
K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ...
Environmental Health Perspectives 128 (2), 027002, 2020
1452020
Environmental impact on vascular development predicted by high-throughput screening
NC Kleinstreuer, RS Judson, DM Reif, NS Sipes, AV Singh, KJ Chandler, ...
Environmental health perspectives 119 (11), 1596-1603, 2011
1432011
An evaluation framework for new approach methodologies (NAMs) for human health safety assessment
ST Parish, M Aschner, W Casey, M Corvaro, MR Embry, S Fitzpatrick, ...
Regulatory Toxicology and Pharmacology 112, 104592, 2020
1402020
Open-source QSAR models for pKa prediction using multiple machine learning approaches
K Mansouri, NF Cariello, A Korotcov, V Tkachenko, CM Grulke, ...
Journal of Cheminformatics 11, 1-20, 2019
1352019
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