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Israel Sekler
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Anno
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange
R Palty, WF Silverman, M Hershfinkel, T Caporale, SL Sensi, J Parnis, ...
Proceedings of the National Academy of Sciences 107 (1), 436-441, 2010
8782010
Zinc in the physiology and pathology of the CNS
SL Sensi, P Paoletti, AI Bush, I Sekler
Nature reviews neuroscience 10 (11), 780-791, 2009
8182009
Role of GPR40 in fatty acid action on the β cell line INS-1E
H Shapiro, S Shachar, I Sekler, M Hershfinkel, MD Walker
Biochemical and biophysical research communications 335 (1), 97-104, 2005
3032005
A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport
M Hershfinkel, A Moran, N Grossman, I Sekler
Proceedings of the National Academy of Sciences 98 (20), 11749-11754, 2001
2892001
Mechanism and regulation of cellular zinc transport
I Sekler, SL Sensi, M Hershfinkel, WF Silverman
Molecular medicine 13, 337-343, 2007
2882007
Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus
L Besser, E Chorin, I Sekler, WF Silverman, S Atkin, JT Russell, ...
Journal of Neuroscience 29 (9), 2890-2901, 2009
2612009
Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter
E Ohana, E Hoch, C Keasar, T Kambe, O Yifrach, M Hershfinkel, I Sekler
Journal of Biological Chemistry 284 (26), 17677-17686, 2009
2162009
NCLX: the mitochondrial sodium calcium exchanger
L Boyman, GSB Williams, D Khananshvili, I Sekler, WJ Lederer
Journal of molecular and cellular cardiology 59, 205-213, 2013
1942013
The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells
AI Tarasov, F Semplici, MA Ravier, EA Bellomo, TJ Pullen, P Gilon, ...
PloS one 7 (7), e39722, 2012
1902012
The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers
TC Pozos, I Seller, MS Cyert
Molecular and cellular biology, 1996
1811996
PKA phosphorylation of NCLX reverses mitochondrial calcium overload and depolarization, promoting survival of PINK1-deficient dopaminergic neurons
M Kostic, MHR Ludtmann, H Bading, M Hershfinkel, E Steer, CT Chu, ...
Cell reports 13 (2), 376-386, 2015
1672015
Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor
E Chorin, O Vinograd, I Fleidervish, D Gilad, S Herrmann, I Sekler, ...
Journal of Neuroscience 31 (36), 12916-12926, 2011
1642011
Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger
R Palty, E Ohana, M Hershfinkel, M Volokita, V Elgazar, O Beharier, ...
Journal of Biological Chemistry 279 (24), 25234-25240, 2004
1592004
The zinc sensing receptor, a link between zinc and cell signaling
M Hershfinkel, WF Silverman, I Sekler
Molecular Medicine 13, 331-336, 2007
1392007
Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity
E Hoch, W Lin, J Chai, M Hershfinkel, D Fu, I Sekler
Proceedings of the National Academy of Sciences 109 (19), 7202-7207, 2012
1322012
Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair
H Sharir, A Zinger, A Nevo, I Sekler, M Hershfinkel
Journal of biological chemistry 285 (34), 26097-26106, 2010
1262010
ZnT‐1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc
C Nolte, A Gore, I Sekler, W Kresse, M Hershfinkel, A Hoffmann, ...
Glia 48 (2), 145-155, 2004
1262004
Distribution of the zinc transporter ZnT‐1 in comparison with chelatable zinc in the mouse brain
I Sekler, A Moran, M Hershfinkel, A Dori, A Margulis, N Birenzweig, ...
Journal of Comparative Neurology 447 (3), 201-209, 2002
1242002
NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD (P) H production and modulating matrix redox state
U De Marchi, J Santo-Domingo, C Castelbou, I Sekler, A Wiederkehr, ...
Journal of Biological Chemistry 289 (29), 20377-20385, 2014
1232014
Mitochondrial exchanger NCLX plays a major role in the intracellular Ca2+ signaling, gliotransmission, and proliferation of astrocytes
J Parnis, V Montana, I Delgado-Martinez, V Matyash, V Parpura, ...
Journal of Neuroscience 33 (17), 7206-7219, 2013
1202013
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