Antonio Lavecchia
Antonio Lavecchia
Professor of Medicinal Chemistry, University of Napoli Federico II
Verified email at unina.it
Title
Cited by
Cited by
Year
Pathogenesis, prevention, diagnosis and treatment of breast cancer
R Shah, K Rosso, SD Nathanson
World journal of clinical oncology 5 (3), 283, 2014
419*2014
Virtual screening strategies in drug discovery: a critical review
A Lavecchia, C Di Giovanni
Current medicinal chemistry 20 (23), 2839-2860, 2013
3792013
Machine-learning approaches in drug discovery: methods and applications
A Lavecchia
Drug discovery today 20 (3), 318-331, 2015
3702015
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure− activity relationships and molecular modeling studies
G La Regina, MC Edler, A Brancale, S Kandil, A Coluccia, F Piscitelli, ...
Journal of medicinal chemistry 50 (12), 2865-2874, 2007
1632007
Docking Studies on αvβ3 Integrin Ligands:  Pharmacophore Refinement and Implications for Drug Design
L Marinelli, A Lavecchia, KE Gottschalk, E Novellino, H Kessler
Journal of medicinal chemistry 46 (21), 4393-4404, 2003
1502003
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide
R Ragno, A Coluccia, G La Regina, G De Martino, F Piscitelli, ...
Journal of medicinal chemistry 49 (11), 3172-3184, 2006
1452006
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2, 6-difluorophenyl) alkyl]-3, 4-dihydro-5-alkylpyrimidin-4 …
A Mai, G Sbardella, M Artico, R Ragno, S Massa, E Novellino, G Greco, ...
Journal of medicinal chemistry 44 (16), 2544-2554, 2001
1302001
In silico methods to address polypharmacology: current status, applications and future perspectives
A Lavecchia, C Cerchia
Drug Discovery Today 21 (2), 288-298, 2016
1232016
Pyrido[1,2-a]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity
C La Motta, S Sartini, L Mugnaini, F Simorini, S Taliani, S Salerno, ...
Journal of Medicinal Chemistry 50 (20), 4917-4927, 2007
1232007
Insights into the mechanism of partial agonism crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complex with two enantiomeric …
G Pochetti, C Godio, N Mitro, D Caruso, A Galmozzi, S Scurati, F Loiodice, ...
Journal of Biological Chemistry 282 (23), 17314-17324, 2007
1222007
New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity
G La Regina, R Silvestri, M Artico, A Lavecchia, E Novellino, O Befani, ...
Journal of medicinal chemistry 50 (5), 922-931, 2007
1192007
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action
R Di Santo, R Costi, A Roux, M Artico, A Lavecchia, L Marinelli, ...
Journal of medicinal chemistry 49 (6), 1939-1945, 2006
1122006
Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic …
R Montanari, F Saccoccia, E Scotti, M Crestani, C Godio, F Gilardi, ...
Journal of medicinal chemistry 51 (24), 7768-7776, 2008
992008
Structure−Activity Studies of the Melanocortin Peptides:  Discovery of Potent and Selective Affinity Antagonists for the hMC3 and hMC4 Receptors
P Grieco, A Lavecchia, M Cai, D Trivedi, D Weinberg, T MacNeil, ...
Journal of medicinal chemistry 45 (24), 5287-5294, 2002
952002
Characterizing the 1,4-Dihydropyridines Binding Interactions in the L-Type Ca2+ Channel:  Model Construction and Docking Calculations
S Cosconati, L Marinelli, A Lavecchia, E Novellino
Journal of medicinal chemistry 50 (7), 1504-1513, 2007
912007
Ligand binding analysis for human α5β1 integrin: strategies for designing new α5β1 integrin antagonists
L Marinelli, A Meyer, D Heckmann, A Lavecchia, E Novellino, H Kessler
Journal of medicinal chemistry 48 (13), 4204-4207, 2005
852005
Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity
A Bolognese, G Correale, M Manfra, A Lavecchia, O Mazzoni, E Novellino, ...
Journal of medicinal chemistry 47 (4), 849-858, 2004
802004
STAT-3 inhibitors: state of the art and new horizons for cancer treatment
A Lavecchia, C Di Giovanni, E Novellino
Current medicinal chemistry 18 (16), 2359-2375, 2011
772011
Synthesis, Cannabinoid Receptor Affinity, and Molecular Modeling Studies of Substituted 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides
R Silvestri, MG Cascio, G La Regina, F Piscitelli, A Lavecchia, A Brizzi, ...
Journal of medicinal chemistry 51 (6), 1560-1576, 2008
762008
CDC25 phosphatase inhibitors: an update
A Lavecchia, C Di Giovanni, E Novellino
Mini reviews in medicinal chemistry 12 (1), 62-73, 2012
752012
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