| Darwinian evolution can follow only very few mutational paths to fitter proteins DM Weinreich, NF Delaney, MA DePristo, DL Hartl science 312 (5770), 111-114, 2006 | 1179 | 2006 |
| Perspective: sign epistasis and genetic costraint on evolutionary trajectories DM Weinreich, RA Watson, L Chao Evolution 59 (6), 1165-1174, 2005 | 607 | 2005 |
| Missense meanderings in sequence space: a biophysical view of protein evolution MA DePristo, DM Weinreich, DL Hartl Nature Reviews Genetics 6 (9), 678-687, 2005 | 599 | 2005 |
| Empirical fitness landscapes reveal accessible evolutionary paths FJ Poelwijk, DJ Kiviet, DM Weinreich, SJ Tans Nature 445 (7126), 383-386, 2007 | 477 | 2007 |
| Stepwise acquisition of pyrimethamine resistance in the malaria parasite ER Lozovsky, T Chookajorn, KM Brown, M Imwong, PJ Shaw, ... Proceedings of the National Academy of Sciences 106 (29), 12025-12030, 2009 | 239 | 2009 |
| Rapid evolutionary escape by large populations from local fitness peaks is likely in nature DM Weinreich, L Chao Evolution 59 (6), 1175-1182, 2005 | 208 | 2005 |
| Should evolutionary geneticists worry about higher-order epistasis? DM Weinreich, Y Lan, CS Wylie, RB Heckendorn Current opinion in genetics & development 23 (6), 700-707, 2013 | 198 | 2013 |
| Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes MF Polz, DE Hunt, SP Preheim, DM Weinreich Philosophical Transactions of the Royal Society B: Biological Sciences 361 …, 2006 | 174 | 2006 |
| The interface of protein structure, protein biophysics, and molecular evolution DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ... Protein Science 21 (6), 769-785, 2012 | 163 | 2012 |
| Causes and evolutionary significance of genetic convergence PA Christin, DM Weinreich, G Besnard Trends in Genetics 26 (9), 400-405, 2010 | 161 | 2010 |
| Contrasting patterns of nonneutral evolution in proteins encoded in nuclear and mitochondrial genomes DM Weinreich, DM Rand Genetics 156 (1), 385-399, 2000 | 123 | 2000 |
| The evolution of phenotypic correlations and “developmental memory” RA Watson, GP Wagner, M Pavlicev, DM Weinreich, R Mills Evolution 68 (4), 1124-1138, 2014 | 71 | 2014 |
| The age of nonsynonymous and synonymous mutations in animal mtDNA and implications for the mildly deleterious theory R Nielsen, DM Weinreich Genetics 153 (1), 497-506, 1999 | 66 | 1999 |
| Widespread genetic exchange among terrestrial bacteriophages OK Silander, DM Weinreich, KM Wright, KJ O'Keefe, CU Rang, PE Turner, ... Proceedings of the National Academy of Sciences 102 (52), 19009-19014, 2005 | 61 | 2005 |
| Widespread genetic exchange among terrestrial bacteriophages OK Silander, DM Weinreich, KM Wright, KJ O'Keefe, CU Rang, PE Turner, ... Proceedings of the National Academy of Sciences 102 (52), 19009-19014, 2005 | 61 | 2005 |
| Mutational reversions during adaptive protein evolution MA DePristo, DL Hartl, DM Weinreich Molecular biology and evolution 24 (8), 1608-1610, 2007 | 55 | 2007 |
| Genome structure and the benefit of sex RA Watson, DM Weinreich, J Wakeley Evolution: International Journal of Organic Evolution 65 (2), 523-536, 2011 | 46 | 2011 |
| Measuring epistasis in fitness landscapes: the correlation of fitness effects of mutations L Ferretti, B Schmiegelt, D Weinreich, A Yamauchi, Y Kobayashi, F Tajima, ... Journal of theoretical biology 396, 132-143, 2016 | 43 | 2016 |
| The rank ordering of genotypic fitness values predicts genetic constraint on natural selection on landscapes lacking sign epistasis DM Weinreich Genetics 171 (3), 1397-1405, 2005 | 42 | 2005 |
| Quantitative description of a protein fitness landscape based on molecular features MR Meini, PE Tomatis, DM Weinreich, AJ Vila Molecular biology and evolution 32 (7), 1774-1787, 2015 | 41 | 2015 |
