|Genetic control of chromatin states in humans involves local and distal chromosomal interactions|
F Grubert, JB Zaugg, M Kasowski, O Ursu, DV Spacek, AR Martin, ...
Cell 162 (5), 1051-1065, 2015
|Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens|
DW Morgens, M Wainberg, EA Boyle, O Ursu, CL Araya, CK Tsui, ...
Nature communications 8 (1), 1-8, 2017
|Measuring the reproducibility and quality of Hi-C data|
GG Yardımcı, H Ozadam, MEG Sauria, O Ursu, KK Yan, T Yang, ...
Genome biology 20 (1), 1-19, 2019
|GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs|
O Ursu, N Boley, M Taranova, YXR Wang, GG Yardimci, W Stafford Noble, ...
Bioinformatics 34 (16), 2701-2707, 2018
|Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements|
J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, A Li, ...
Nature communications 10 (1), 1-14, 2019
|SAMNet: a network-based approach to integrate multi-dimensional high throughput datasets|
SJC Gosline, SJ Spencer, O Ursu, E Fraenkel
Integrative Biology 4 (11), 1415-1427, 2012
|Network modelling of topological domains using Hi-C data|
YXR Wang, P Sarkar, O Ursu, A Kundaje, PJ Bickel
The annals of applied statistics 13 (3), 1511, 2019
|Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations|
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
|Methods and compositions for massively parallel variant and small molecule phenotyping|
A Regev, P Thakore, J Doench, JT Neal, J Boehm, O Ursu
US Patent App. 16/809,458, 2020
|Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens|
O Ursu, SJC Gosline, N Beeharry, L Fink, V Bhattacharjee, SC Huang, ...
PloS one 12 (10), e0185650, 2017
|Unsupervised learning from noisy networks with applications to Hi-C data|
B Wang, J Zhu, A Pourshafeie, O Ursu, S Batzoglou, A Kundaje
Advances in Neural Information Processing Systems 29, 3305-3313, 2016
|Understanding Gene Regulation and Genetic Variation Through the Lens of Three-Dimensional Genome Architecture|
Stanford University, 2018