| A comprehensive comparison of transmembrane domains reveals organelle-specific properties HJ Sharpe, TJ Stevens, S Munro Cell 142 (1), 158-169, 2010 | 564 | 2010 |
| Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD CA Colton, RT Mott, H Sharpe, Q Xu, WE Van Nostrand, MP Vitek Journal of neuroinflammation 3, 1-12, 2006 | 494 | 2006 |
| Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma X Bonilla, L Parmentier, B King, F Bezrukov, G Kaya, V Zoete, ... Nature genetics 48 (4), 398-406, 2016 | 447 | 2016 |
| Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma HJ Sharpe, G Pau, GJ Dijkgraaf, N Basset-Seguin, Z Modrusan, ... Cancer cell 27 (3), 327-341, 2015 | 401 | 2015 |
| Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates K Strisovsky, HJ Sharpe, M Freeman Molecular cell 36 (6), 1048-1059, 2009 | 211 | 2009 |
| Regulation of the oncoprotein Smoothened by small molecules HJ Sharpe, W Wang, RN Hannoush, FJ De Sauvage Nature chemical biology 11 (4), 246-255, 2015 | 130 | 2015 |
| A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14 Y Herzig, HJ Sharpe, Y Elbaz, S Munro, M Schuldiner PLoS biology 10 (5), e1001329, 2012 | 106 | 2012 |
| Efficacy of Hedgehog pathway inhibitors in Basal cell carcinoma N Basset-Seguin, HJ Sharpe, FJ de Sauvage Molecular cancer therapeutics 14 (3), 633-641, 2015 | 90 | 2015 |
| The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell–cell adhesion GW Fearnley, KA Young, JR Edgar, R Antrobus, IM Hay, WC Liang, ... Elife 8, e44597, 2019 | 31 | 2019 |
| Protein tyrosine phosphatases in cell adhesion KA Young, L Biggins, HJ Sharpe Biochemical Journal 478 (5), 1061-1083, 2021 | 28 | 2021 |
| The dead phosphatases society: a review of the emerging roles of pseudophosphatases V Reiterer, K Pawłowski, G Desrochers, A Pause, HJ Sharpe, H Farhan The FEBS journal 287 (19), 4198-4220, 2020 | 27 | 2020 |
| Accelerated waning of the humoral response to COVID-19 vaccines in obesity AA Van Der Klaauw, EC Horner, P Pereyra-Gerber, U Agrawal, WS Foster, ... Nature Medicine 29 (5), 1146-1154, 2023 | 19 | 2023 |
| The receptor PTPRU is a redox sensitive pseudophosphatase IM Hay, GW Fearnley, P Rios, M Köhn, HJ Sharpe, JE Deane Nature Communications 11 (1), 3219, 2020 | 18 | 2020 |
| Membrane topology of the endoplasmic reticulum to Golgi transport factor Erv29p DA Foley, HJ Sharpe, DA Foley, HJ Sharpe, S Otte Molecular membrane biology 24 (4), 259-268, 2007 | 17 | 2007 |
| An oxysterol ligand for Smoothened HJ Sharpe, FJ de Sauvage Nature Chemical Biology 8 (2), 139-140, 2012 | 11 | 2012 |
| Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination WS Foster, J Le Lee, N Thakur, J Newman, AJ Spencer, S Davies, ... Cell Reports Medicine 3 (12), 2022 | 9 | 2022 |
| Frequency and genomic aspects of intrinsic resistance to vismodegib in locally advanced basal cell carcinoma AA Yurchenko, OT Pop, M Ighilahriz, I Padioleau, F Rajabi, HJ Sharpe, ... Clinical Cancer Research 28 (7), 1422-1432, 2022 | 6 | 2022 |
| Accelerated waning of the humoral response to SARS-CoV-2 vaccines in obesity AA van der Klaauw, EC Horner, P Pereyra-Gerber, U Agrawal, WS Foster, ... medRxiv, 2022.06. 09.22276196, 2022 | 5 | 2022 |
| Grking the Smoothened signal HJ Sharpe, FJ de Sauvage Science Signaling 11 (516), eaar6377, 2018 | 5 | 2018 |
| Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly I Drissi, E Fletcher, R Shaheen, M Nahorski, AM Alhashem, S Lisgo, ... Journal of Medical Genetics 59 (4), 358-365, 2022 | 3 | 2022 |
