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Simon C Johnson
Simon C Johnson
Email verificata su northumbria.ac.uk - Home page
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mTOR is a key modulator of ageing and age-related disease
SC Johnson, PS Rabinovitch, M Kaeberlein
Nature 493 (7432), 338-345, 2013
18652013
Mitochondrial oxidative stress mediates angiotensin II–induced cardiac hypertrophy and Gαq overexpression–induced heart failure
DF Dai, SC Johnson, JJ Villarin, MT Chin, M Nieves-Cintrón, T Chen, ...
Circulation research 108 (7), 837-846, 2011
5592011
Mitochondrial oxidative stress mediates angiotensin II–induced cardiac hypertrophy and Gαq overexpression–induced heart failure
DF Dai, SC Johnson, JJ Villarin, MT Chin, M Nieves-Cintrón, T Chen, ...
Circulation research 108 (7), 837-846, 2011
5592011
Mitochondrial oxidative stress mediates angiotensin II–induced cardiac hypertrophy and Gαq overexpression–induced heart failure
DF Dai, SC Johnson, JJ Villarin, MT Chin, M Nieves-Cintrón, T Chen, ...
Circulation research 108 (7), 837-846, 2011
5592011
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome
SC Johnson, ME Yanos, EB Kayser, A Quintana, M Sangesland, ...
Science 342 (6165), 1524-1528, 2013
5122013
Targeted therapy in patients with PIK3CA-related overgrowth syndrome
Q Venot, T Blanc, SH Rabia, L Berteloot, S Ladraa, JP Duong, E Blanc, ...
Nature 558 (7711), 540-546, 2018
4592018
Cardiac aging: from molecular mechanisms to significance in human health and disease
DF Dai, T Chen, SC Johnson, H Szeto, PS Rabinovitch
Antioxidants & redox signaling 16 (12), 1492-1526, 2012
3432012
A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging
MA McCormick, JR Delaney, M Tsuchiya, S Tsuchiyama, A Shemorry, ...
Cell metabolism 22 (5), 895-906, 2015
2492015
Assessment of cell viability
S Johnson, V Nguyen, D Coder
Current protocols in cytometry 64 (1), 9.2. 1-9.2. 26, 2013
2072013
Molecular mechanisms underlying genotype‐dependent responses to dietary restriction
J Schleit, SC Johnson, CF Bennett, M Simko, N Trongtham, A Castanza, ...
Aging cell 12 (6), 1050-1061, 2013
1702013
New generation of artificial MicroRNA and synthetic trans-acting small interfering RNA vectors for efficient gene silencing in Arabidopsis
A Carbonell, A Takeda, N Fahlgren, SC Johnson, JT Cuperus, ...
Plant physiology 165 (1), 15-29, 2014
1472014
Modulating mTOR in aging and health
SC Johnson, M Sangesland, M Kaeberlein, PS Rabinovitch
Aging and health-A systems biology perspective 40, 107-127, 2015
1112015
Genomewide meta‐analysis identifies loci associated with IGF‐I and IGFBP‐3 levels with impact on age‐related traits
A Teumer, Q Qi, M Nethander, H Aschard, S Bandinelli, M Beekman, ...
Aging cell 15 (5), 811-824, 2016
912016
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice
SC Johnson, M Yanos, M Sangesland, A Bitto, A Gagnidze, J Cordoba, ...
Frontiers in genetics 6, 155155, 2015
902015
Genetic evidence for common pathways in human age‐related diseases
SC Johnson, X Dong, J Vijg, Y Suh
Aging cell 14 (5), 809-817, 2015
882015
Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy
AH Kahn-Kirby, A Amagata, CI Maeder, JJ Mei, S Sideris, Y Kosaka, ...
PLoS One 14 (3), e0214250, 2019
632019
Ex vivo imaging of excised tissue using vital dyes and confocal microscopy
S Johnson, P Rabinovitch
Current protocols in cytometry 61 (1), 9.39. 1-9.39. 18, 2012
632012
Nutrient sensing, signaling and ageing: the role of IGF-1 and mTOR in ageing and age-related disease
SC Johnson
Biochemistry and Cell Biology of Ageing: Part I Biomedical Science, 49-97, 2018
602018
Paracrine activation of hepatic stellate cells in platelet‐derived growth factor C transgenic mice: evidence for stromal induction of hepatocellular carcinoma
JH Wright, MM Johnson, M Shimizu‐Albergine, RL Bauer, BJ Hayes, ...
International journal of cancer 134 (4), 778-788, 2014
602014
Sir2 deletion prevents lifespan extension in 32 long‐lived mutants
JR Delaney, GL Sutphin, B Dulken, S Sim, JR Kim, B Robison, J Schleit, ...
Aging cell 10 (6), 1089-1091, 2011
592011
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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