RNA splicing modulation selectively impairs leukemia stem cell maintenance in secondary human AML LA Crews, L Balaian, NPD Santos, HS Leu, E Lazzari, A Sadarangani, ... Cell Stem Cell 19 (5), 599-612, 2016 | 114 | 2016 |
Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1 L Mirandola, L Apicella, M Colombo, Y Yu, DG Berta, N Platonova, ... Leukemia 27 (7), 1558-1566, 2013 | 103 | 2013 |
Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma E Lazzari, PK Mondala, ND Santos, AC Miller, G Pineda, Q Jiang, H Leu, ... Nature communications 8 (1), 1922, 2017 | 101 | 2017 |
Hyper-editing of cell-cycle regulatory and tumor suppressor RNA promotes malignant progenitor propagation Q Jiang, J Isquith, MA Zipeto, RH Diep, J Pham, ND Santos, E Reynoso, ... Cancer cell 35 (1), 81-94. e7, 2019 | 73 | 2019 |
Notch signaling drives multiple myeloma induced osteoclastogenesis M Colombo, K Thümmler, L Mirandola, S Garavelli, K Todoerti, L Apicella, ... Oncotarget 5 (21), 10393, 2014 | 68 | 2014 |
An RNA editing fingerprint of cancer stem cell reprogramming LA Crews, Q Jiang, MA Zipeto, E Lazzari, AC Court, S Ali, CL Barrett, ... Journal of translational medicine 13, 1-12, 2015 | 59 | 2015 |
Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF P Ramalingam, MG Poulos, E Lazzari, MC Gutkin, D Lopez, CC Kloss, ... Nature communications 11 (1), 666, 2020 | 54 | 2020 |
Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche M Colombo, S Galletti, G Bulfamante, M Falleni, D Tosi, K Todoerti, ... Oncotarget 7 (35), 56013, 2016 | 44 | 2016 |
PI3K/AKT signaling inhibits NOTCH1 lysosome‐mediated degradation N Platonova, T Manzo, L Mirandola, M Colombo, E Calzavara, E Vigolo, ... Genes, Chromosomes and Cancer 54 (8), 516-526, 2015 | 30 | 2015 |
Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance M Colombo, S Garavelli, M Mazzola, N Platonova, D Giannandrea, ... Haematologica 105 (7), 1925, 2020 | 25 | 2020 |
The Instructive Role of the Bone Marrow Niche in Aging and Leukemia E Lazzari, JM Butler Current Stem Cell Reports 4 (4), 291-298, 2018 | 21 | 2018 |
Endothelial mTOR maintains hematopoiesis during aging P Ramalingam, MG Poulos, MC Gutkin, L Katsnelson, AG Freire, ... Journal of Experimental Medicine 217 (6), 2020 | 20 | 2020 |
Tracking of normal and malignant progenitor cell cycle transit in a defined niche G Pineda, KM Lennon, NP Delos Santos, F Lambert-Fliszar, GL Riso, ... Scientific reports 6 (1), 23885, 2016 | 13 | 2016 |
Notch signaling dysregulation promotes multiple myeloma-associated bone disease S Garavelli, M Colombo, K Thümmler, L Apicella, M Lancellotti, E Lazzari, ... Clinical Lymphoma Myeloma and Leukemia 15, e233, 2015 | 3 | 2015 |
Aging of the Vascular Niche Enhances Leukemia-Initiating Cell Metabolic Switch E Lazzari, P Ramalingam, MG Poulos, JM Butler Blood 132 (Suppl 1), 871, 2018 | 1 | 2018 |
ADAR1-MediatedGLI1 Editing Promotes Malignant Self-Renewal in Multiple Myeloma L Crews, E Lazzari, P Mondala, ND Santos, A Miller, G Pineda, Q Jiang, ... Blood 130, 1204, 2017 | 1 | 2017 |
Targeting Cancer Stem Cell Survival in Plasma Cell Leukemia with a Pan-BCL2 Inhibitor E Lazzari, LA Crews, C Wu, H Leu, R Chiaramonte, MD Minden, ... Blood 126 (23), 5351, 2015 | 1 | 2015 |
Multiple myeloma-associated drug resistance: targeting the Notch pathway S Garavelli, E Lazzari, M Colombo, A Paoli, A Moschini, N Platonova, ... Haematologica 100 (suppl. 3), 159-159, 2015 | 1 | 2015 |
Promotion of human multiple myeloma cell growth in vitro and bone marrow invasion in vivo by Notch receptors and the CXCR4/SDF1 axis. M Chiriva-Internati, L Mirandola, E Lazzari, M Colombo, M Lancellotti, ... Journal of Clinical Oncology 31 (15_suppl), 8591-8591, 2013 | 1 | 2013 |
INFLAMMATION OF THE VASCULAR NICHE ENHANCES LEUKEMIA-INITIATING CELL METABOLIC SWITCH E Lazzari, P Ramalingam, M Gutkin, M Poulos, J Butler Experimental Hematology 76, S73, 2019 | | 2019 |