Dieter Steinhilber
Dieter Steinhilber
Professor für Pharmazeutische Chemie
Email verificata su - Home page
Citata da
Citata da
5-Lipoxygenase: regulation of expression and enzyme activity
O Rådmark, O Werz, D Steinhilber, B Samuelsson
Trends in biochemical sciences 32 (7), 332-341, 2007
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease
O Rådmark, O Werz, D Steinhilber, B Samuelsson
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human B lymphocytes
D Steinhilber, M Brungs, O Werz, I Wiesenberg, C Danielsson, JP Kahlen, ...
Journal of Biological Chemistry 270 (13), 7037-7040, 1995
Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase
D Albert, I Zündorf, T Dingermann, WE Müller, D Steinhilber, O Werz
Biochemical pharmacology 64 (12), 1767-1775, 2002
Therapeutic options for 5-lipoxygenase inhibitors
O Werz, D Steinhilber
Pharmacology & therapeutics 112 (3), 701-718, 2006
5-Lipoxygenase: a target for antiinflammatory drugs revisited
D Steinhilber
Current medicinal chemistry 6 (1), 71-86, 1999
Vitamin D in inflammatory diseases
TK Wöbke, BL Sorg, D Steinhilber
Frontiers in physiology 5, 244, 2014
Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes
O Werz, E Bürkert, B Samuelsson, O Rådmark, D Steinhilber
Blood, The Journal of the American Society of Hematology 99 (3), 1044-1052, 2002
Extracellular signal‐regulated kinases phosphorylate 5lipoxygenase and stimulate 5‐lipoxygenase product formation in leukocytes
O Werz, E Bürkert, L Fischer, D Szellas, D Dishart, B Samuelsson, ...
The FASEB Journal 16 (11), 1441-1443, 2002
Development of 5-lipoxygenase inhibitors—lessons from cellular enzyme regulation
O Werz, D Steinhilber
Biochemical pharmacology 70 (3), 327-333, 2005
Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1, 25-dihydroxyvitamin D3
M Brungs, O Rådmark, B Samuelsson, D Steinhilber
Proceedings of the National Academy of Sciences 92 (1), 107-111, 1995
Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse
D Kerjaschki, Z Bago-Horvath, M Rudas, V Sexl, C Schneckenleithner, ...
The Journal of clinical investigation 121 (5), 2000-2012, 2011
Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2)
O Werz, D Szellas, D Steinhilber, O Rådmark
Journal of Biological Chemistry 277 (17), 14793-14800, 2002
Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes
D Poeckel, C Greiner, M Verhoff, O Rau, L Tausch, C Hörnig, ...
Biochemical pharmacology 76 (1), 91-97, 2008
Phosphorylation‐and stimulus‐dependent inhibition of cellular 5‐lipoxygenase activity by nonredox‐type inhibitors
L Fischer, D Szellas, O Rådmark, D Steinhilber, O Werz
The FASEB journal 17 (8), 1-24, 2003
On the expression and regulation of 5-lipoxygenase in human lymphocytes.
PJ Jakobsson, D Steinhilber, B Odlander, O Rådmark, HE Claesson, ...
Proceedings of the National Academy of Sciences 89 (8), 3521-3525, 1992
The 5-lipoxygenase promoter is regulated by DNA methylation
J Uhl, N Klan, M Rose, KD Entian, O Werz, D Steinhilber
Journal of Biological Chemistry 277 (6), 4374-4379, 2002
Medizinische Chemie
D Steinhilber, M Schubert-Zsilavecz, H Roth
Hirzel Verlag, 2017
Bioactivity-guided mapping and navigation of chemical space
S Renner, WAL Van Otterlo, MD Seoane, S Möcklinghoff, B Hofmann, ...
Nature chemical biology 5 (8), 585-592, 2009
Inhibitors of the arachidonic acid cascade: interfering with multiple pathways
K Meirer, D Steinhilber, E Proschak
Basic & clinical pharmacology & toxicology 114 (1), 83-91, 2014
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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