| 5-Lipoxygenase: regulation of expression and enzyme activity O Rådmark, O Werz, D Steinhilber, B Samuelsson Trends in biochemical sciences 32 (7), 332-341, 2007 | 551 | 2007 |
| 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease O Rådmark, O Werz, D Steinhilber, B Samuelsson Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 496 | 2015 |
| The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human b lymphocytes (∗) D Steinhilber, M Brungs, O Werz, I Wiesenberg, C Danielsson, JP Kahlen, ... Journal of Biological Chemistry 270 (13), 7037-7040, 1995 | 339 | 1995 |
| Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase D Albert, I Zündorf, T Dingermann, WE Müller, D Steinhilber, O Werz Biochemical pharmacology 64 (12), 1767-1775, 2002 | 338 | 2002 |
| Vitamin D in inflammatory diseases TK Wöbke, BL Sorg, D Steinhilber Frontiers in physiology 5, 244, 2014 | 332 | 2014 |
| Therapeutic options for 5-lipoxygenase inhibitors O Werz, D Steinhilber Pharmacology & therapeutics 112 (3), 701-718, 2006 | 327 | 2006 |
| 5-Lipoxygenase: a target for antiinflammatory drugs revisited D Steinhilber Current medicinal chemistry 6 (1), 71-86, 1999 | 251 | 1999 |
| Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes O Werz, E Bürkert, B Samuelsson, O Rådmark, D Steinhilber Blood, The Journal of the American Society of Hematology 99 (3), 1044-1052, 2002 | 230 | 2002 |
| Extracellular signal‐regulated kinases phosphorylate 5lipoxygenase and stimulate 5‐lipoxygenase product formation in leukocytes O Werz, E Bürkert, L Fischer, D Szellas, D Dishart, B Samuelsson, ... The FASEB Journal 16 (11), 1441-1443, 2002 | 198 | 2002 |
| Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse D Kerjaschki, Z Bago-Horvath, M Rudas, V Sexl, C Schneckenleithner, ... The Journal of clinical investigation 121 (5), 2000-2012, 2011 | 197 | 2011 |
| Development of 5-lipoxygenase inhibitors—lessons from cellular enzyme regulation O Werz, D Steinhilber Biochemical pharmacology 70 (3), 327-333, 2005 | 194 | 2005 |
| Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes D Poeckel, C Greiner, M Verhoff, O Rau, L Tausch, C Hörnig, ... Biochemical pharmacology 76 (1), 91-97, 2008 | 183 | 2008 |
| Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1, 25-dihydroxyvitamin D3. M Brungs, O Rådmark, B Samuelsson, D Steinhilber Proceedings of the National Academy of Sciences 92 (1), 107-111, 1995 | 177 | 1995 |
| Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2) O Werz, D Szellas, D Steinhilber, O Rådmark Journal of biological chemistry 277 (17), 14793-14800, 2002 | 173 | 2002 |
| Phosphorylation‐and stimulus‐dependent inhibition of cellular 5‐lipoxygenase activity by nonredox‐type inhibitors L Fischer, D Szellas, O Rådmark, D Steinhilber, O Werz The FASEB journal 17 (8), 1-24, 2003 | 170 | 2003 |
| Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells P Guillem-Llobat, M Dovizio, A Bruno, E Ricciotti, V Cufino, A Sacco, ... Oncotarget 7 (22), 32462, 2016 | 164 | 2016 |
| Inhibitors of the arachidonic acid cascade: interfering with multiple pathways K Meirer, D Steinhilber, E Proschak Basic & clinical pharmacology & toxicology 114 (1), 83-91, 2014 | 162 | 2014 |
| On the expression and regulation of 5-lipoxygenase in human lymphocytes. PJ Jakobsson, D Steinhilber, B Odlander, O Rådmark, HE Claesson, ... Proceedings of the National Academy of Sciences 89 (8), 3521-3525, 1992 | 161 | 1992 |
| Bioactivity-guided mapping and navigation of chemical space S Renner, WAL Van Otterlo, M Dominguez Seoane, S Möcklinghoff, ... Nature chemical biology 5 (8), 585-592, 2009 | 155 | 2009 |
| The 5-lipoxygenase promoter is regulated by DNA methylation J Uhl, N Klan, M Rose, KD Entian, O Werz, D Steinhilber Journal of Biological Chemistry 277 (6), 4374-4379, 2002 | 149 | 2002 |
