| Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5276 | 2021 |
| Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ... The Lancet 396 (10267), 1979-1993, 2020 | 1655 | 2020 |
| Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1325 | 2021 |
| Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor A Vannini, C Volpari, G Filocamo, EC Casavola, M Brunetti, D Renzoni, ... Proceedings of the National Academy of Sciences 101 (42), 15064-15069, 2004 | 782 | 2004 |
| HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics P Gallinari, SD Marco, P Jones, M Pallaoro, C Steinkühler Cell research 17 (3), 195-211, 2007 | 701 | 2007 |
| The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA A Vannini, C Volpari, C Gargioli, E Muraglia, R Cortese, R De Francesco, ... The EMBO journal 21 (17), 4393-4401, 2002 | 444 | 2002 |
| Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone PRE Mittl, S Di Marco, JF Krebs, X Bai, DS Karanewsky, JP Priestle, ... Journal of Biological Chemistry 272 (10), 6539-6547, 1997 | 364 | 1997 |
| Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex A Vannini, C Volpari, P Gallinari, P Jones, M Mattu, A Carfí, ... EMBO reports 8 (9), 879-884, 2007 | 301 | 2007 |
| A monovalent chimpanzee adenovirus Ebola vaccine boosted with MVA K Ewer, T Rampling, N Venkatraman, G Bowyer, D Wright, T Lambe, ... New England Journal of Medicine 374 (17), 1635-1646, 2016 | 298 | 2016 |
| The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis H Blanchard, L Kodandapani, PRE Mittl, S Di Marco, JF Krebs, JC Wu, ... Structure 7 (9), 1125-1133, 1999 | 240 | 1999 |
| Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site S Di Marco, C Volpari, L Tomei, S Altamura, S Harper, F Narjes, U Koch, ... Journal of Biological Chemistry 280 (33), 29765-29770, 2005 | 205 | 2005 |
| A PCSK9-binding antibody that structurally mimics the EGF (A) domain of LDL-receptor reduces LDL cholesterol in vivo 1 [S] YG Ni, S Di Marco, JH Condra, LB Peterson, W Wang, F Wang, S Pandit, ... Journal of lipid research 52 (1), 78-86, 2011 | 174 | 2011 |
| Domains of interaction between alpha interferon and its receptor components G Uzé, S Di Marco, E Mouchel-Vielh, D Monneron, MT Bandu, ... Journal of molecular biology 243 (2), 245-257, 1994 | 153 | 1994 |
| Inhibition of the hepatitis C virus NS3/4A protease: the crystal structures of two protease-inhibitor complexes S Di Marco, M Rizzi, C Volpari, MA Walsh, F Narjes, S Colarusso, ... Journal of Biological Chemistry 275 (10), 7152-7157, 2000 | 148 | 2000 |
| A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density … YG Ni, JH Condra, L Orsatti, X Shen, S Di Marco, S Pandit, MJ Bottomley, ... Journal of Biological Chemistry 285 (17), 12882-12891, 2010 | 143 | 2010 |
| Chimpanzee adenovirus–and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults CA Green, E Scarselli, CJ Sande, AJ Thompson, CM De Lara, KS Taylor, ... Science translational medicine 7 (300), 300ra126-300ra126, 2015 | 141 | 2015 |
| A monovalent chimpanzee adenovirus Ebola vaccine—preliminary report T Rampling, K Ewer, G Bowyer, D Wright, E Imoukhuede, R Payne, ... New England Journal of Medicine, 2015 | 138 | 2015 |
| Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions RO Payne, SE Silk, SC Elias, K Miura, A Diouf, F Galaway, H De Graaf, ... JCI insight 2 (21), 2017 | 136 | 2017 |
| A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH M Osman, A Mistry, A Keding, R Gabe, E Cook, S Forrester, R Wiggins, ... PLoS neglected tropical diseases 11 (5), e0005527, 2017 | 133 | 2017 |
| Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase S Harper, S Avolio, B Pacini, M Di Filippo, S Altamura, L Tomei, ... Journal of medicinal chemistry 48 (14), 4547-4557, 2005 | 131 | 2005 |
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